ES8207184A1 - Procedimiento para la preparacion de composiciones fosfoli- pidicas de colina - Google Patents

Procedimiento para la preparacion de composiciones fosfoli- pidicas de colina

Info

Publication number
ES8207184A1
ES8207184A1 ES502080A ES502080A ES8207184A1 ES 8207184 A1 ES8207184 A1 ES 8207184A1 ES 502080 A ES502080 A ES 502080A ES 502080 A ES502080 A ES 502080A ES 8207184 A1 ES8207184 A1 ES 8207184A1
Authority
ES
Spain
Prior art keywords
pharmaceutical composition
oral administration
administration containing
containing cytidine
cytidine diphosphocholine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502080A
Other languages
English (en)
Other versions
ES502080A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Made Italiana SRL
Original Assignee
Made Italiana SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Made Italiana SRL filed Critical Made Italiana SRL
Publication of ES8207184A1 publication Critical patent/ES8207184A1/es
Publication of ES502080A0 publication Critical patent/ES502080A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPOSICIONES FOSFOLIPIDICAS DE COLINA. CONSISTE EN COMBINAR MOLECULARMENTE CITIDIN-DIFOSFOCOLINA O UNA SAL SUYA CON UNA SUSTANCIA DEL GRUPO DE LOS FOSFOLIPIDOS,PREFERENTEMENTE LA LECITINA LA LECITINA, EN CUYA REALIZACION SE TRATA CON UN SOLUCION DE LA CITIDIN-DIFOSFOCOLINA UN FOSFOLIPIDO EN ESTADO SOLIDO,EMULSION O SOLUCION,MANTENIENDO UNA RELACION PONDERAL DE UN MATERIAL PROTEICO Y AGENTES DE RETICULACION, SECANDO DESPUES E PRODUCTO OBTENIDO A UNA TEMPERATURA NO SUPERIOR A 70-80 C.
ES502080A 1980-04-18 1981-04-15 Procedimiento para la preparacion de composiciones fosfoli- pidicas de colina Granted ES502080A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8048454A IT1207106B (it) 1980-04-18 1980-04-18 Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale

Publications (2)

Publication Number Publication Date
ES8207184A1 true ES8207184A1 (es) 1982-09-01
ES502080A0 ES502080A0 (es) 1982-09-01

Family

ID=11266633

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502080A Granted ES502080A0 (es) 1980-04-18 1981-04-15 Procedimiento para la preparacion de composiciones fosfoli- pidicas de colina

Country Status (15)

Country Link
US (1) US4386077A (es)
AT (1) AT376366B (es)
AU (1) AU544469B2 (es)
BE (1) BE890796A (es)
CH (1) CH652026A5 (es)
DE (1) DE3115080C2 (es)
DK (1) DK173081A (es)
ES (1) ES502080A0 (es)
FR (1) FR2480603B1 (es)
GB (1) GB2074445B (es)
IN (1) IN156105B (es)
IT (1) IT1207106B (es)
NL (1) NL8101899A (es)
SE (1) SE447449B (es)
ZA (1) ZA812600B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569929A (en) * 1980-02-29 1986-02-11 Massachusetts Institute Of Technology Cytidyl diphosphocholine-drug composition
EP0114577A1 (en) * 1983-01-21 1984-08-01 MAGIS FARMACEUTICI S.p.A. New pharmaceutical composition
IT1201474B (it) * 1985-10-01 1989-02-02 Vincenzo Zappia Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
EP0566135A1 (en) * 1992-04-17 1993-10-20 Takeda Chemical Industries, Ltd. Transmucosal composition comprising a peptide and a cytidine derivative
AU2005201251B2 (en) * 1995-03-06 2006-04-27 Interneuron Pharmaceuticals, Inc. Reduction of infarct volume using citicoline
US5872108A (en) * 1995-03-06 1999-02-16 Interneuron Pharmaceuticals, Inc. Reduction of infarct volume using citicoline
AU1640400A (en) * 1995-03-06 2000-04-20 Interneuron Pharmaceuticals, Inc. Reduction of infarct volume using citicoline
CN1126546C (zh) * 1995-03-06 2003-11-05 英特纽隆制剂药有限公司 使用胞磷胆碱减少梗塞面积
ES2425114T3 (es) * 2000-03-16 2013-10-11 The Mclean Hospital Corporation CDP-colina y uridina para el tratamiento del abuso del acohol
EP1604671A4 (en) * 2003-02-26 2006-03-29 Kyowa Hakko Kogyo Kk MUSCLE TRAINING AGENT AND PREVENTION AND CARE PROVIDER IN THE EVENT OF MUSCLE DEGREASING
EP1765364A4 (en) * 2004-06-10 2010-09-22 Mclean Hospital Corp PYRIMIDINES, SUCH AS Z: B: CYTIDINE, IN THE TREATMENT OF PATIENTS WITH BIPOLAR DISORDER
WO2005122767A1 (en) * 2004-06-10 2005-12-29 Mclean Hospital Corporation Pyrimidines, such as uridine, in treatments for patients with bipolar disorder
EP1784199A4 (en) * 2004-08-11 2010-06-23 Mclean Hospital Corp COMPOUNDS FOR TREATING MARIHUANA DEPENDENCE, DEDUCTION AND CONSUMPTION
US20100041621A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods and compositions for improving cognitive performance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3666748A (en) * 1967-12-18 1972-05-30 Takeda Chemical Industries Ltd Method for production of cytidine (or deoxycytidine)-5{40 -diphosphate choline and intermediates therefor
NL149812B (nl) * 1969-04-24 1976-06-15 Takeda Chemical Industries Ltd Werkwijze ter bereiding van farmaceutische preparaten, alsmede werkwijze ter bereiding van kristallijn cytidine-5'-difosfaat-choline-monohydraat.
JPS4841555B1 (es) * 1969-08-04 1973-12-07
JPS4886869A (es) * 1972-02-23 1973-11-15

Also Published As

Publication number Publication date
IT1207106B (it) 1989-05-17
BE890796A (fr) 1982-02-15
IN156105B (es) 1985-05-18
AU544469B2 (en) 1985-05-30
US4386077A (en) 1983-05-31
SE8102456L (sv) 1981-10-19
NL8101899A (nl) 1981-11-16
ES502080A0 (es) 1982-09-01
IT8048454A0 (it) 1980-04-18
FR2480603B1 (fr) 1985-07-12
AT376366B (de) 1984-11-12
DE3115080A1 (de) 1982-02-25
GB2074445A (en) 1981-11-04
ZA812600B (en) 1982-04-28
FR2480603A1 (fr) 1981-10-23
ATA172081A (de) 1984-04-15
DK173081A (da) 1981-10-19
DE3115080C2 (de) 1986-10-16
AU6994581A (en) 1981-10-22
CH652026A5 (it) 1985-10-31
GB2074445B (en) 1983-09-07
SE447449B (sv) 1986-11-17

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