IT1207106B - Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale - Google Patents

Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale

Info

Publication number
IT1207106B
IT1207106B IT8048454A IT4845480A IT1207106B IT 1207106 B IT1207106 B IT 1207106B IT 8048454 A IT8048454 A IT 8048454A IT 4845480 A IT4845480 A IT 4845480A IT 1207106 B IT1207106 B IT 1207106B
Authority
IT
Italy
Prior art keywords
disfofocolina
citidin
pharmaceutical preparation
preparation containing
absorbable
Prior art date
Application number
IT8048454A
Other languages
English (en)
Other versions
IT8048454A0 (it
Inventor
Eraldo Borgo
Original Assignee
Made Italiana Srl Ora Searle I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Made Italiana Srl Ora Searle I filed Critical Made Italiana Srl Ora Searle I
Publication of IT8048454A0 publication Critical patent/IT8048454A0/it
Priority to IT8048454A priority Critical patent/IT1207106B/it
Priority to CH2491/81A priority patent/CH652026A5/it
Priority to GB8111849A priority patent/GB2074445B/en
Priority to DE3115080A priority patent/DE3115080C2/de
Priority to SE8102456A priority patent/SE447449B/sv
Priority to ES502080A priority patent/ES502080A0/es
Priority to DK173081A priority patent/DK173081A/da
Priority to AT0172081A priority patent/AT376366B/de
Priority to NL8101899A priority patent/NL8101899A/nl
Priority to FR8107759A priority patent/FR2480603B1/fr
Priority to ZA00812600A priority patent/ZA812600B/xx
Priority to US06/257,538 priority patent/US4386077A/en
Priority to AU69945/81A priority patent/AU544469B2/en
Priority to BE0/206294A priority patent/BE890796A/fr
Priority to IN308/CAL/82A priority patent/IN156105B/en
Application granted granted Critical
Publication of IT1207106B publication Critical patent/IT1207106B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT8048454A 1980-04-18 1980-04-18 Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale IT1207106B (it)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IT8048454A IT1207106B (it) 1980-04-18 1980-04-18 Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale
CH2491/81A CH652026A5 (it) 1980-04-18 1981-04-14 Preparazione assorbibile per via orale farmaceutica contenente cididin difosfocolina.
GB8111849A GB2074445B (en) 1980-04-18 1981-04-14 Oral pharmaceutical compositions containing cytidine diphospholine
DE3115080A DE3115080C2 (de) 1980-04-18 1981-04-14 Arzneimittel enthaltend Cytidindiphosphocholin und Lecithin
DK173081A DK173081A (da) 1980-04-18 1981-04-15 Farmaceutisk produkt til oral administration indeholdende cytidindiphosphocholin
ES502080A ES502080A0 (es) 1980-04-18 1981-04-15 Procedimiento para la preparacion de composiciones fosfoli- pidicas de colina
SE8102456A SE447449B (sv) 1980-04-18 1981-04-15 Farmaceutisk komposition innehallande cytidindifosfokolin och vegetabiliska fosfolipider
AT0172081A AT376366B (de) 1980-04-18 1981-04-15 Verfahren zur herstellung eines arzneimittels
NL8101899A NL8101899A (nl) 1980-04-18 1981-04-16 Farmaceutisch preparaat voor orale toediening met daarin cytidinedifosfocholine.
FR8107759A FR2480603B1 (fr) 1980-04-18 1981-04-17 Composition pharmaceutique pour administration par voie orale contenant de la cytidine-diphosphocholine
ZA00812600A ZA812600B (en) 1980-04-18 1981-04-21 A pharmaceutical composition for oral administration containing cytidin diphosphocholine
US06/257,538 US4386077A (en) 1980-04-18 1981-04-27 Pharmaceutical composition for oral administration containing cytidine diphosphocholine
AU69945/81A AU544469B2 (en) 1980-04-18 1981-04-29 Oral administration of cytidin diphosphocholine
BE0/206294A BE890796A (fr) 1980-04-18 1981-10-20 Composition pharmaceutique pour administration par voie orale contenant de la cytidine-diphosphocholine
IN308/CAL/82A IN156105B (it) 1980-04-18 1982-03-19

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8048454A IT1207106B (it) 1980-04-18 1980-04-18 Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale

Publications (2)

Publication Number Publication Date
IT8048454A0 IT8048454A0 (it) 1980-04-18
IT1207106B true IT1207106B (it) 1989-05-17

Family

ID=11266633

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8048454A IT1207106B (it) 1980-04-18 1980-04-18 Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale

Country Status (15)

Country Link
US (1) US4386077A (it)
AT (1) AT376366B (it)
AU (1) AU544469B2 (it)
BE (1) BE890796A (it)
CH (1) CH652026A5 (it)
DE (1) DE3115080C2 (it)
DK (1) DK173081A (it)
ES (1) ES502080A0 (it)
FR (1) FR2480603B1 (it)
GB (1) GB2074445B (it)
IN (1) IN156105B (it)
IT (1) IT1207106B (it)
NL (1) NL8101899A (it)
SE (1) SE447449B (it)
ZA (1) ZA812600B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569929A (en) * 1980-02-29 1986-02-11 Massachusetts Institute Of Technology Cytidyl diphosphocholine-drug composition
EP0114577A1 (en) * 1983-01-21 1984-08-01 MAGIS FARMACEUTICI S.p.A. New pharmaceutical composition
IT1201474B (it) * 1985-10-01 1989-02-02 Vincenzo Zappia Derivati macromolecolarizzati di cdp-colina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
EP0566135A1 (en) * 1992-04-17 1993-10-20 Takeda Chemical Industries, Ltd. Transmucosal composition comprising a peptide and a cytidine derivative
US5872108A (en) * 1995-03-06 1999-02-16 Interneuron Pharmaceuticals, Inc. Reduction of infarct volume using citicoline
AU1640400A (en) * 1995-03-06 2000-04-20 Interneuron Pharmaceuticals, Inc. Reduction of infarct volume using citicoline
PT813416E (pt) * 1995-03-06 2005-10-31 Interneuron Pharma Reducao do volume de enfarte usando citicolina
AU2005201251B2 (en) * 1995-03-06 2006-04-27 Interneuron Pharmaceuticals, Inc. Reduction of infarct volume using citicoline
US8030294B2 (en) * 2000-03-16 2011-10-04 The Mclean Hospital Corporation Compounds for the treatment of psychiatric or substance abuse disorders
WO2004075905A1 (ja) * 2003-02-26 2004-09-10 Kyowa Hakko Kogyo Co., Ltd. 筋肉増強剤および筋肉減衰の予防または治療剤
EP1765075A4 (en) * 2004-06-10 2010-11-10 Mclean Hospital Corp PYRIMIDINES, IN PARTICULAR URIDINE, USED IN TREATMENTS ON PATIENTS WITH BIPOLAR DISORDERS
WO2005123097A1 (en) * 2004-06-10 2005-12-29 Mclean Hospital Corporation Pyrimidines, such as cytidine, in treatments for patients with bipolar disorder
US7947661B2 (en) * 2004-08-11 2011-05-24 The Mclean Hospital Corporation Compounds for the treatment of marihuana dependence, withdrawal, and usage
US20100041621A1 (en) * 2008-08-15 2010-02-18 Perry Renshaw Methods and compositions for improving cognitive performance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3666748A (en) * 1967-12-18 1972-05-30 Takeda Chemical Industries Ltd Method for production of cytidine (or deoxycytidine)-5{40 -diphosphate choline and intermediates therefor
NL149812B (nl) * 1969-04-24 1976-06-15 Takeda Chemical Industries Ltd Werkwijze ter bereiding van farmaceutische preparaten, alsmede werkwijze ter bereiding van kristallijn cytidine-5'-difosfaat-choline-monohydraat.
JPS4841555B1 (it) * 1969-08-04 1973-12-07
JPS4886869A (it) * 1972-02-23 1973-11-15

Also Published As

Publication number Publication date
ES8207184A1 (es) 1982-09-01
FR2480603A1 (fr) 1981-10-23
CH652026A5 (it) 1985-10-31
IN156105B (it) 1985-05-18
AT376366B (de) 1984-11-12
US4386077A (en) 1983-05-31
ZA812600B (en) 1982-04-28
IT8048454A0 (it) 1980-04-18
AU6994581A (en) 1981-10-22
DK173081A (da) 1981-10-19
NL8101899A (nl) 1981-11-16
AU544469B2 (en) 1985-05-30
BE890796A (fr) 1982-02-15
SE447449B (sv) 1986-11-17
SE8102456L (sv) 1981-10-19
FR2480603B1 (fr) 1985-07-12
GB2074445B (en) 1983-09-07
ES502080A0 (es) 1982-09-01
DE3115080C2 (de) 1986-10-16
DE3115080A1 (de) 1982-02-25
GB2074445A (en) 1981-11-04
ATA172081A (de) 1984-04-15

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