ES8609299A1 - Procedimiento para la obtencion de derivados de flavanona - Google Patents

Procedimiento para la obtencion de derivados de flavanona

Info

Publication number
ES8609299A1
ES8609299A1 ES546493A ES546493A ES8609299A1 ES 8609299 A1 ES8609299 A1 ES 8609299A1 ES 546493 A ES546493 A ES 546493A ES 546493 A ES546493 A ES 546493A ES 8609299 A1 ES8609299 A1 ES 8609299A1
Authority
ES
Spain
Prior art keywords
derivatives
flavanon
alkoxy
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546493A
Other languages
English (en)
Other versions
ES546493A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES546493A0 publication Critical patent/ES546493A0/es
Publication of ES8609299A1 publication Critical patent/ES8609299A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER DERIVADOS DE FLAVANONA. CONSISTE EN HACER REACCIONAR A UNA FLAVANONA D.F. (II) CON UN ALDEHIDO D.F. (III), EN ETANOL O TETRAHIDROFURANO, EN PRESENCIA DE UN CATALIZADOR ACIDO COMO ACIDO SULFURICO O ACIDO FOSFORICO Y ENTRE 0 Y 150JC, PARA OBTENER UN C.D.F. (I), SUS ESTERES DE ACIDO FOSFORICO Y SUS SALES UTILIZABLES EN MEDICINA Y VETERINARIA. SIENDO AR1 Y AR2 FENILO INSUSTITUIDO UNA O TRES VECES POR OH, ALQUILO, ALCOXI, ACILAMINO, HAL, COO, ALQUILO Y OTROS; Y C.D.F., COMPUESTO D.F., Y D.F., DE FORMULA. SE UTILIZAN PARA COMBATIR ALERGIAS E INFECCIONES BACTERIALES EN ANIMALES Y EN EL HOMBRE.
ES546493A 1984-08-28 1985-08-28 Procedimiento para la obtencion de derivados de flavanona Expired ES8609299A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843431534 DE3431534A1 (de) 1984-08-28 1984-08-28 Flavanonderivate

Publications (2)

Publication Number Publication Date
ES546493A0 ES546493A0 (es) 1986-07-16
ES8609299A1 true ES8609299A1 (es) 1986-07-16

Family

ID=6244043

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546493A Expired ES8609299A1 (es) 1984-08-28 1985-08-28 Procedimiento para la obtencion de derivados de flavanona

Country Status (19)

Country Link
US (1) US4937257A (es)
EP (1) EP0173186B1 (es)
JP (1) JPH0674259B2 (es)
KR (1) KR930002101B1 (es)
AR (1) AR241246A1 (es)
AT (1) ATE39351T1 (es)
AU (1) AU586827B2 (es)
CA (1) CA1270484A (es)
DD (1) DD236313A5 (es)
DE (2) DE3431534A1 (es)
DK (1) DK389985A (es)
ES (1) ES8609299A1 (es)
FI (1) FI84061C (es)
HU (1) HU194901B (es)
IE (1) IE58202B1 (es)
IL (1) IL76188A (es)
NZ (1) NZ213236A (es)
PT (1) PT81029B (es)
ZA (1) ZA856521B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0518750U (ja) * 1991-08-23 1993-03-09 新東工業株式会社 鋳造品取り出し装置
DE4314871A1 (de) * 1993-05-05 1994-11-10 Merck Patent Gmbh Lösungsmittel für ein schwerlösliches Gentamicin-Salz
DE19521642C2 (de) * 1995-06-14 2000-11-09 Aesculap Ag & Co Kg Implantat, seine Verwendung in der Chirurgie und Verfahren zu seiner Herstellung
DE19856668A1 (de) * 1998-12-09 2000-06-15 Aesculap Ag & Co Kg Wirkstoffmatrix in Form eines biologisch resorbierbaren porösen Vlieses, Verfahren zu ihrer Herstellung und Verwendung
EP1957507B1 (en) 2005-12-02 2018-10-24 Ionis Pharmaceuticals, Inc. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
KR101504115B1 (ko) 2007-03-12 2015-03-19 삼성전자 주식회사 매크로 명령 동작 장치와 매크로 명령 입력 장치 및 방법
CN101715455A (zh) * 2007-04-10 2010-05-26 尔察祯有限公司 抗菌的1,4,5-取代的氨基糖苷类似物
JP5315572B2 (ja) * 2007-08-30 2013-10-16 国立大学法人 千葉大学 フラボノイドの製造方法
WO2010030690A1 (en) 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
JP2013507391A (ja) 2009-10-09 2013-03-04 アカオジェン インコーポレイテッド 抗ウイルスアミノグリコシド類似体
WO2012067978A1 (en) 2010-11-17 2012-05-24 Achaogen, Inc. Antibacterial amiinoglycoside analogs
RU2015144051A (ru) * 2013-03-15 2017-04-27 ЭйПиАй ДЖЕНИСИС ЭлЭлСи Композиции полифенолов/флавоноидов и способы получения гигиенических продуктов для полости рта
DE102015214603B4 (de) * 2015-07-31 2019-01-24 Mathys Ag Bettlach Phosphorhaltige Aminoglycosid-Salze
CN115160280B (zh) * 2022-06-07 2023-08-04 贵州农业职业学院 一种黄烷酮类化合物的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3678044A (en) * 1970-10-22 1972-07-18 Chevron Res Substituted flavanones
US4241069A (en) * 1979-09-04 1980-12-23 Miles Laboratories, Inc. 3-Methylene flavanones and 3-methylene chromanones
GB2122987B (en) * 1982-06-01 1985-09-25 Zyma Sa (+)-cyanidan-3-ol derivatives and pharmaceutical preparations thereof
GB8323291D0 (en) * 1983-08-31 1983-10-05 Zyma Sa Flavanone and thioflavanone derivatives

Also Published As

Publication number Publication date
IE58202B1 (en) 1993-07-28
ZA856521B (en) 1986-04-30
US4937257A (en) 1990-06-26
EP0173186A1 (de) 1986-03-05
CA1270484A (en) 1990-06-19
EP0173186B1 (de) 1988-12-21
JPS6160677A (ja) 1986-03-28
AU586827B2 (en) 1989-07-27
DK389985D0 (da) 1985-08-27
PT81029A (en) 1985-09-01
NZ213236A (en) 1988-05-30
IE852120L (en) 1986-02-28
ES546493A0 (es) 1986-07-16
HUT40096A (en) 1986-11-28
DD236313A5 (de) 1986-06-04
KR930002101B1 (ko) 1993-03-26
JPH0674259B2 (ja) 1994-09-21
AR241246A1 (es) 1992-03-31
DK389985A (da) 1986-03-01
PT81029B (pt) 1987-12-30
AU4664885A (en) 1986-03-06
ATE39351T1 (de) 1989-01-15
IL76188A0 (en) 1985-12-31
FI853277A0 (fi) 1985-08-27
HU194901B (en) 1988-03-28
DE3566887D1 (de) 1989-01-26
KR860001798A (ko) 1986-03-22
IL76188A (en) 1990-11-29
FI84061C (fi) 1991-10-10
FI84061B (fi) 1991-06-28
FI853277L (fi) 1986-03-01
DE3431534A1 (de) 1986-03-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050504