JPS57176979A - Novel derivative of secalonic acid and its preparation - Google Patents
Novel derivative of secalonic acid and its preparationInfo
- Publication number
- JPS57176979A JPS57176979A JP6191681A JP6191681A JPS57176979A JP S57176979 A JPS57176979 A JP S57176979A JP 6191681 A JP6191681 A JP 6191681A JP 6191681 A JP6191681 A JP 6191681A JP S57176979 A JPS57176979 A JP S57176979A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- preparation
- secalonic acid
- novel derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(R is alkyl, aryl, aralkyl which may contain substituent group) and its salt.
EXAMPLE: 4,4'-Bis(ethoxycarbonylaminomethyl)-secalonic acid A.
USE: A carcinostatic. Having low toxicity.
PROCESS: A compound shown by the formula II is reacted with a compound shown by the formula HO-CH2-NH-CO2R or formula CH2(-NH-CO2R)2' or a compound shown by the formula III is reacted with a compound shown by the formula Cl-CO2R, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6191681A JPS57176979A (en) | 1981-04-25 | 1981-04-25 | Novel derivative of secalonic acid and its preparation |
US06/366,333 US4418061A (en) | 1981-04-16 | 1982-04-07 | Secalonic acid derivatives and method for preparing thereof |
EP82103231A EP0064199B1 (en) | 1981-04-16 | 1982-04-16 | Novel secalonic acid derivatives and method for preparing thereof |
DE8282103231T DE3265553D1 (en) | 1981-04-16 | 1982-04-16 | Novel secalonic acid derivatives and method for preparing thereof |
US06/529,635 US4556651A (en) | 1981-04-16 | 1983-09-06 | Secalonic acid derivatives as antitumor agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6191681A JPS57176979A (en) | 1981-04-25 | 1981-04-25 | Novel derivative of secalonic acid and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57176979A true JPS57176979A (en) | 1982-10-30 |
JPH0128753B2 JPH0128753B2 (en) | 1989-06-05 |
Family
ID=13184960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6191681A Granted JPS57176979A (en) | 1981-04-16 | 1981-04-25 | Novel derivative of secalonic acid and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57176979A (en) |
-
1981
- 1981-04-25 JP JP6191681A patent/JPS57176979A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPH0128753B2 (en) | 1989-06-05 |
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