JPS57176979A - Novel derivative of secalonic acid and its preparation - Google Patents

Novel derivative of secalonic acid and its preparation

Info

Publication number
JPS57176979A
JPS57176979A JP6191681A JP6191681A JPS57176979A JP S57176979 A JPS57176979 A JP S57176979A JP 6191681 A JP6191681 A JP 6191681A JP 6191681 A JP6191681 A JP 6191681A JP S57176979 A JPS57176979 A JP S57176979A
Authority
JP
Japan
Prior art keywords
compound shown
formula
preparation
secalonic acid
novel derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6191681A
Other languages
Japanese (ja)
Other versions
JPH0128753B2 (en
Inventor
Kazuyuki Shibuya
Kunihiko Ishii
Mitsuru Shibukawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Priority to JP6191681A priority Critical patent/JPS57176979A/en
Priority to US06/366,333 priority patent/US4418061A/en
Priority to EP82103231A priority patent/EP0064199B1/en
Priority to DE8282103231T priority patent/DE3265553D1/en
Publication of JPS57176979A publication Critical patent/JPS57176979A/en
Priority to US06/529,635 priority patent/US4556651A/en
Publication of JPH0128753B2 publication Critical patent/JPH0128753B2/ja
Granted legal-status Critical Current

Links

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  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(R is alkyl, aryl, aralkyl which may contain substituent group) and its salt.
EXAMPLE: 4,4'-Bis(ethoxycarbonylaminomethyl)-secalonic acid A.
USE: A carcinostatic. Having low toxicity.
PROCESS: A compound shown by the formula II is reacted with a compound shown by the formula HO-CH2-NH-CO2R or formula CH2(-NH-CO2R)2' or a compound shown by the formula III is reacted with a compound shown by the formula Cl-CO2R, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP6191681A 1981-04-16 1981-04-25 Novel derivative of secalonic acid and its preparation Granted JPS57176979A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP6191681A JPS57176979A (en) 1981-04-25 1981-04-25 Novel derivative of secalonic acid and its preparation
US06/366,333 US4418061A (en) 1981-04-16 1982-04-07 Secalonic acid derivatives and method for preparing thereof
EP82103231A EP0064199B1 (en) 1981-04-16 1982-04-16 Novel secalonic acid derivatives and method for preparing thereof
DE8282103231T DE3265553D1 (en) 1981-04-16 1982-04-16 Novel secalonic acid derivatives and method for preparing thereof
US06/529,635 US4556651A (en) 1981-04-16 1983-09-06 Secalonic acid derivatives as antitumor agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6191681A JPS57176979A (en) 1981-04-25 1981-04-25 Novel derivative of secalonic acid and its preparation

Publications (2)

Publication Number Publication Date
JPS57176979A true JPS57176979A (en) 1982-10-30
JPH0128753B2 JPH0128753B2 (en) 1989-06-05

Family

ID=13184960

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6191681A Granted JPS57176979A (en) 1981-04-16 1981-04-25 Novel derivative of secalonic acid and its preparation

Country Status (1)

Country Link
JP (1) JPS57176979A (en)

Also Published As

Publication number Publication date
JPH0128753B2 (en) 1989-06-05

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