ES8607945A1 - Procedimiento de preparacion de derivados imidazolidinos - Google Patents

Procedimiento de preparacion de derivados imidazolidinos

Info

Publication number
ES8607945A1
ES8607945A1 ES543446A ES543446A ES8607945A1 ES 8607945 A1 ES8607945 A1 ES 8607945A1 ES 543446 A ES543446 A ES 543446A ES 543446 A ES543446 A ES 543446A ES 8607945 A1 ES8607945 A1 ES 8607945A1
Authority
ES
Spain
Prior art keywords
alkyl
halogen
image
general formula
imidazolidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543446A
Other languages
English (en)
Other versions
ES543446A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES543446A0 publication Critical patent/ES543446A0/es
Publication of ES8607945A1 publication Critical patent/ES8607945A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS IMIDAZOLINOS Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES; Y N VALE 9-4. CONSISTE EN LA REACCION DE ETILENDIAMIDA CON UN DITIOESTER DE FORMULA (II), EN LA QUE Z REPRESENTA OXIGENO O AZUFRE, R8 ES ARILO, ALQUILO O ARIL-ALQUILO INFERIOR, Y R Y N TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y LA DE EBULLICION DE LA MEZCLA DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES HIPOTENSIVAS, DIURETICAS, DISMINUIDORAS DE LA PRESION INTRAOCULAR Y ANOVULATORIAS.
ES543446A 1984-05-23 1985-05-23 Procedimiento de preparacion de derivados imidazolidinos Expired ES8607945A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU198184A HU192986B (en) 1984-05-23 1984-05-23 Process for production of imidasodiline derivatives

Publications (2)

Publication Number Publication Date
ES543446A0 ES543446A0 (es) 1986-06-16
ES8607945A1 true ES8607945A1 (es) 1986-06-16

Family

ID=10957138

Family Applications (3)

Application Number Title Priority Date Filing Date
ES543446A Expired ES8607945A1 (es) 1984-05-23 1985-05-23 Procedimiento de preparacion de derivados imidazolidinos
ES552082A Expired ES8705399A1 (es) 1984-05-23 1986-02-17 Procedimiento de preparacion de derivados imidazolidinos
ES552081A Expired ES8705398A1 (es) 1984-05-23 1986-02-17 Procedimiento de preparacion de derivados imidazolidinos

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES552082A Expired ES8705399A1 (es) 1984-05-23 1986-02-17 Procedimiento de preparacion de derivados imidazolidinos
ES552081A Expired ES8705398A1 (es) 1984-05-23 1986-02-17 Procedimiento de preparacion de derivados imidazolidinos

Country Status (12)

Country Link
JP (1) JPS60255773A (es)
DD (1) DD233373A5 (es)
DE (1) DE3518604A1 (es)
DK (1) DK232385A (es)
ES (3) ES8607945A1 (es)
FI (1) FI852059L (es)
FR (1) FR2564833B1 (es)
GB (1) GB2160198B (es)
GR (1) GR851272B (es)
HU (1) HU192986B (es)
PT (1) PT80516B (es)
SE (1) SE8502544L (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3719015A1 (de) * 1987-06-06 1988-12-15 Basf Ag Verfahren zur herstellung von iminokohlensaeurediarylestern
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
DE10106214A1 (de) * 2001-02-10 2002-08-14 Boehringer Ingelheim Pharma Neue Alkyl-phenylimino-imidazolidin-Derivate zur Behandlung der Harninkontinenz

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2899426A (en) 1959-08-11 Synthesis of l
DE842065C (de) 1950-07-30 1952-06-23 Bayer Ag Verfahren zur Herstellung stickstoffhaltiger heterocyclischer Verbindungen
DE1795517U (de) 1959-06-26 1959-09-10 Vorwerk & Sohn Hitzebestaendiger schlauch, insbesondere kabeldurchfuehrungs- und -kuehlschlauch.
GB889706A (en) 1960-07-16 1962-02-21 Thomas Adam Clayton Fungicidal composition
US3236857A (en) 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1303930C2 (de) 1963-09-20 1976-10-14 Ausscheidung aus: 13 03 929 CH. Boehringer Sohn, 6507 Ingelheim 2-(2-chlor-4-methyl- oder-aethyl- anilino)-1,3- diazacyclopenten-(2), deren salze sowie ein verfahren zu deren herstellung
FR6998M (es) 1965-10-01 1969-06-02
ES352379A1 (es) 1967-05-26 1969-08-01 Boehringer Sohn Ingelheim Procedimiento para la preparacion de 1,3-diazaciclopenteno-(2) sustituido en posicion 2.
DE1670230A1 (de) 1967-05-26 1971-01-21 Boehringer Sohn Ingelheim Neues Verfahren zur Herstellung von in 2-Stellung substituierten 1,3-Diazacycloalkenen(2)
FR1577217A (es) 1967-06-19 1969-08-08
DE1770872A1 (de) 1968-08-26 1972-01-13 Dresden Arzneimittel Verfahren zur Herstellung von Imidazolin-2-Derivaten
FI50411C (fi) 1972-05-19 1976-03-10 Laeaeketehdas Oy Star Ab Menetelmä aryyliamino-2-imidatsoliinien valmistamiseksi
ES409418A1 (es) 1972-12-07 1976-01-01 Medichem Sa Procedimiento para la obtencion de derivados de halogenoa- nilinas.
DE2316377C3 (de) 1973-04-02 1978-11-02 Lentia Gmbh, Chem. U. Pharm. Erzeugnisse - Industriebedarf, 8000 Muenchen Verfahren zur Herstellung von 2-Phenyl-amino-2-imidazolin-Derivaten und von deren Salzen
AT330769B (de) 1974-04-05 1976-07-26 Chemie Linz Ag Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen
YU39236B (en) 1974-07-03 1984-10-31 Chemie Linz Ag Process for preparing new 2-arylamino-2-imidazoline derivatives
DE2446758C3 (de) 1974-10-01 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie
GB1506913A (en) 1975-03-18 1978-04-12 Chemie Linz Ag Process for the preparation of 2-phenylamino-2-imidazoline derivatives
YU135677A (en) 1976-06-10 1982-08-31 Financial Mining Ind Ship Improved method of concentrating pure magnesite
JPS54119458A (en) 1978-03-02 1979-09-17 Daiwa Yakuhin Kougiyou Kk Manufacture of 22phenylaminoimidazolinee2
DE2830278A1 (de) * 1978-07-10 1980-01-31 Boehringer Sohn Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2831657A1 (de) * 1978-07-19 1980-02-07 Boehringer Sohn Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2854659A1 (de) * 1978-12-18 1980-07-10 Boehringer Sohn Ingelheim Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
DE2900538A1 (de) 1979-01-08 1980-07-17 Dso Pharmachim Verfahren zur herstellung von 2-(phenylamino)-imidazolinen-(2)
US4290971A (en) 1979-01-19 1981-09-22 Dso "Pharmachim" Method of preparing 2-(phenylamino)-imidazolines-(2)
BE877428A (fr) 1979-07-03 1980-01-03 Dso Pharmachim Procede de preparation de 2-(phenylamino)-imidazolines-(2).
DE2933930A1 (de) * 1979-08-22 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.
DE2949287A1 (de) * 1979-12-07 1981-06-11 C.H. Boehringer Sohn, 6507 Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
US4287201A (en) 1980-03-03 1981-09-01 Merck & Co., Inc. Anovulatory method and chicken feed compositions

Also Published As

Publication number Publication date
PT80516A (en) 1985-06-01
ES543446A0 (es) 1986-06-16
FI852059L (fi) 1985-11-24
DD233373A5 (de) 1986-02-26
ES8705398A1 (es) 1987-05-01
ES552082A0 (es) 1987-05-01
GB8513031D0 (en) 1985-06-26
ES8705399A1 (es) 1987-05-01
GB2160198B (en) 1988-02-24
HU192986B (en) 1987-08-28
FR2564833B1 (fr) 1989-04-14
SE8502544L (sv) 1985-11-24
HUT37762A (en) 1986-02-28
PT80516B (en) 1986-12-16
SE8502544D0 (sv) 1985-05-23
GB2160198A (en) 1985-12-18
GR851272B (es) 1985-11-25
DE3518604A1 (de) 1985-11-28
FR2564833A1 (fr) 1985-11-29
JPS60255773A (ja) 1985-12-17
FI852059A0 (fi) 1985-05-23
ES552081A0 (es) 1987-05-01
DK232385A (da) 1985-11-24
DK232385D0 (da) 1985-05-23

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