ES8602653A1 - Un procedimiento para la separacion de serotonina - Google Patents

Un procedimiento para la separacion de serotonina

Info

Publication number
ES8602653A1
ES8602653A1 ES533890A ES533890A ES8602653A1 ES 8602653 A1 ES8602653 A1 ES 8602653A1 ES 533890 A ES533890 A ES 533890A ES 533890 A ES533890 A ES 533890A ES 8602653 A1 ES8602653 A1 ES 8602653A1
Authority
ES
Spain
Prior art keywords
wax
prepn
water
soln
coffee
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533890A
Other languages
English (en)
Other versions
ES533890A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Nestle SA
Original Assignee
Societe des Produits Nestle SA
Nestle SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe des Produits Nestle SA, Nestle SA filed Critical Societe des Produits Nestle SA
Publication of ES8602653A1 publication Critical patent/ES8602653A1/es
Publication of ES533890A0 publication Critical patent/ES533890A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • External Artificial Organs (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA SEPARACION DE LA SEROTONINA DE CERA DEL CAFE, EN PARTICULAR PARA LA PREPARACION DE CIERTOS DERIVADOS DE LA SEROTONINA, DE FORMULA GENERAL (I). CONSISTE EN SOMETER UNA SOLUCION DE CERA DE CAFE A HIDROLISIS ALCALINA, UTILIZANDO UNA BASE FUERTE Y EN PRESENCIA DE AGUA EN UNA ATMOSFERA INERTE. A CONTINUACION SE RECUPERA EL MEDIO REACCIONAL QUE CONTIENE LA SEROTONINA. EL DISOLVENTE PARA LA CERA DEL CAFE ES UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R ES HIDROGENO O UN GRUPO ALQUILO QUE CONTIENE 1 A 4 ATOMOS DE CARBONO; X ES 0 O 1; Y N ES UN NUMERO ENTERO DE 2 A 4, CON LA SALVEDAD DE QUE X NO PUEDE TENER EL VALOR 1 CUANDO N ES 3 O 4.DE APLICACION EN EL TRATAMIENTO DE LA PSICOSIS, MIGRAÑA Y PARA EL CONTROL DE FUMAR EN EXCESO.
ES533890A 1983-07-01 1984-06-30 Un procedimiento para la separacion de serotonina Granted ES533890A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/510,167 US4506080A (en) 1983-07-01 1983-07-01 Preparation of serotonine and derivatives

Publications (2)

Publication Number Publication Date
ES8602653A1 true ES8602653A1 (es) 1985-12-16
ES533890A0 ES533890A0 (es) 1985-12-16

Family

ID=24029637

Family Applications (4)

Application Number Title Priority Date Filing Date
ES533890A Granted ES533890A0 (es) 1983-07-01 1984-06-30 Un procedimiento para la separacion de serotonina
ES545232A Granted ES545232A0 (es) 1983-07-01 1985-07-16 Un procedimiento para la preparacion de mexamina
ES545231A Expired ES8604142A1 (es) 1983-07-01 1985-07-16 Un procedimiento para la preparacion de melatonina
ES545230A Granted ES545230A0 (es) 1983-07-01 1985-07-16 Un procedimiento para la preparacion de n-acetil serotonina

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES545232A Granted ES545232A0 (es) 1983-07-01 1985-07-16 Un procedimiento para la preparacion de mexamina
ES545231A Expired ES8604142A1 (es) 1983-07-01 1985-07-16 Un procedimiento para la preparacion de melatonina
ES545230A Granted ES545230A0 (es) 1983-07-01 1985-07-16 Un procedimiento para la preparacion de n-acetil serotonina

Country Status (10)

Country Link
US (1) US4506080A (es)
EP (3) EP0130303B1 (es)
JP (4) JPS6025966A (es)
AT (2) ATE38514T1 (es)
DE (1) DE3462794D1 (es)
ES (4) ES533890A0 (es)
GB (3) GB2142622B (es)
IL (1) IL71737A (es)
OA (1) OA07734A (es)
ZM (1) ZM3384A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877176A (en) * 1991-12-26 1999-03-02 Cornell Research Foundation, Inc. Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis
US6080773A (en) * 1997-10-14 2000-06-27 Akzo Nobel, N.V. Benzylamine derivatives which are useful in treating psychiatric disorders
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
IL155666A (en) * 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
CN104496882A (zh) * 2014-11-29 2015-04-08 湖北金赛药业有限公司 一种褪黑素的合成方法
JP2021522196A (ja) * 2018-04-20 2021-08-30 ザ ジェネラル ホスピタル コーポレイション 血液脳関門を越えて送達するためのアセチル化プロドラッグ
CN110105261A (zh) * 2018-12-24 2019-08-09 武汉工程大学 一种利用微反应器连续、快速合成及提纯褪黑素的方法
ES1237024Y (es) 2019-09-20 2020-01-30 Normagrup Tech S A Dispositivo de iluminacion autonomo para la regulacion de ciclos circadianos
CN113402437B (zh) * 2021-06-29 2023-07-14 河北维达康生物科技有限公司 一种合成膳食补充剂褪黑素的新方法
CN113788780B (zh) * 2021-10-15 2023-06-16 河北维达康生物科技有限公司 一种n-乙酰基-5-甲氧基色胺的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2156944C3 (de) * 1971-11-16 1974-10-17 Hag Ag, 2800 Bremen Verfahren zur Gewinnung von Serotonin aus Kaffeewachs
CH568719A5 (en) * 1973-08-22 1975-11-14 Haco Ag Extracting carboxylic acid 5-hydroxy-tryptamide irritants - from coffee without caffeine extn. by using caffeine - enriched solvents
DE2435365A1 (de) * 1973-12-31 1976-01-29 Luigi Di Bella Pharmazeutisches mittel fuer die behandlung von allen leukaemieformen und neurotischen syndromen
CH601227A5 (es) * 1975-05-30 1978-06-30 Nestle Sa
CH608790A5 (en) * 1976-11-18 1979-01-31 Nestle Sa Process for separating serotonin from coffee waxes

Also Published As

Publication number Publication date
ES8603411A1 (es) 1986-01-01
ATE38513T1 (de) 1988-11-15
JPS6445363A (en) 1989-02-17
EP0197390B1 (en) 1988-11-09
EP0197390A2 (en) 1986-12-03
ATE38514T1 (de) 1988-11-15
DE3462794D1 (en) 1987-04-30
ES8603410A1 (es) 1986-01-01
JPH0438748B2 (es) 1992-06-25
JPS6410511B2 (es) 1989-02-22
ES545232A0 (es) 1986-01-01
EP0197390A3 (en) 1986-12-03
ES8604142A1 (es) 1986-01-16
EP0197389A2 (en) 1986-12-03
GB2165838A (en) 1986-04-23
GB2142622A (en) 1985-01-23
JPS6025966A (ja) 1985-02-08
JPH0438747B2 (es) 1992-06-25
ES545230A0 (es) 1986-01-01
EP0130303B1 (en) 1987-03-25
GB2142622B (en) 1987-04-01
OA07734A (fr) 1985-08-30
GB8411197D0 (en) 1984-06-06
EP0197389A3 (en) 1986-12-03
IL71737A0 (en) 1984-09-30
GB2165838B (en) 1987-04-01
EP0130303A1 (en) 1985-01-09
US4506080A (en) 1985-03-19
GB2165837B (en) 1987-04-01
GB2165837A (en) 1986-04-23
GB8521543D0 (en) 1985-10-02
IL71737A (en) 1987-07-31
JPH0466866B2 (es) 1992-10-26
JPS6445361A (en) 1989-02-17
JPS6445362A (en) 1989-02-17
GB8521544D0 (en) 1985-10-02
ES533890A0 (es) 1985-12-16
ES545231A0 (es) 1986-01-16
EP0197389B1 (en) 1988-11-09
ZM3384A1 (en) 1984-12-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001