JPS6452794A - Sialic acid-containing thioglycerolipid derivative and production thereof - Google Patents

Sialic acid-containing thioglycerolipid derivative and production thereof

Info

Publication number
JPS6452794A
JPS6452794A JP10527888A JP10527888A JPS6452794A JP S6452794 A JPS6452794 A JP S6452794A JP 10527888 A JP10527888 A JP 10527888A JP 10527888 A JP10527888 A JP 10527888A JP S6452794 A JPS6452794 A JP S6452794A
Authority
JP
Japan
Prior art keywords
formula
compound expressed
thioglycerolipid
derivative
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10527888A
Other languages
Japanese (ja)
Inventor
Yuji Matsuzaki
Shoji Yoshimura
Masayoshi Ito
Yoshiyasu Shijima
Tomoya Ogawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
Mect Corp
Original Assignee
KANTO ISHI PHARMA CO Ltd
Mect Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KANTO ISHI PHARMA CO Ltd, Mect Corp filed Critical KANTO ISHI PHARMA CO Ltd
Priority to JP10527888A priority Critical patent/JPS6452794A/en
Publication of JPS6452794A publication Critical patent/JPS6452794A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound expressed by formula I or II (Ac is acetyl; R<1> and R<2> are 1-30C alkyl). EXAMPLE:3-S-[Sodium(5-acetamido-3,5-dideoxy-alpha-D-glycero-D-galacto- 2-nonulopy ranosyl)-onate]-1,2-di-O-tetradecyl-Sn-thioglycerol expressed by formula III. USE:A remedy for neuropathic diseases. PREPARATION:A compound expressed by formula IV (R<3> is lower alkyl) is reacted with a compound expressed by formula V (X is halogen) in a polar solvent to provide a compound expressed by formula VI, which is then reacted with a sodium alkoxide in absolute alcohol. The resultant compound expressed by formula VII is subsequently reacted with sodium hydroxide in a polar solvent.
JP10527888A 1987-05-29 1988-04-27 Sialic acid-containing thioglycerolipid derivative and production thereof Pending JPS6452794A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10527888A JPS6452794A (en) 1987-05-29 1988-04-27 Sialic acid-containing thioglycerolipid derivative and production thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13407687 1987-05-29
JP10527888A JPS6452794A (en) 1987-05-29 1988-04-27 Sialic acid-containing thioglycerolipid derivative and production thereof

Publications (1)

Publication Number Publication Date
JPS6452794A true JPS6452794A (en) 1989-02-28

Family

ID=26445598

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10527888A Pending JPS6452794A (en) 1987-05-29 1988-04-27 Sialic acid-containing thioglycerolipid derivative and production thereof

Country Status (1)

Country Link
JP (1) JPS6452794A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991013079A1 (en) 1990-02-27 1991-09-05 Drug Delivery System Institute, Ltd. Derivative of glycolipid containing sialic acid
JPH06507263A (en) * 1990-02-27 1994-08-11 ボード　オブ　トラスティーズ　リーランド　スタンフォード　ジュニア　ユニバーシティ Adaptive judgment feedback equalizer device for processing information stored on digital storage media
US6337390B1 (en) 1996-05-16 2002-01-08 Nissan Food Products Co., Ltd. Compounds comprising sulfated nonulonic acid having antiviral activity
US6444649B1 (en) 1998-04-10 2002-09-03 Mitsubishi Chemical Corporation Solid dispersion containing sialic acid derivative

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991013079A1 (en) 1990-02-27 1991-09-05 Drug Delivery System Institute, Ltd. Derivative of glycolipid containing sialic acid
US5243035A (en) * 1990-02-27 1993-09-07 Drug Delivery System Institute, Ltd. Sialic acid-containing glycolipid derivatives
JPH06507263A (en) * 1990-02-27 1994-08-11 ボード　オブ　トラスティーズ　リーランド　スタンフォード　ジュニア　ユニバーシティ Adaptive judgment feedback equalizer device for processing information stored on digital storage media
US6337390B1 (en) 1996-05-16 2002-01-08 Nissan Food Products Co., Ltd. Compounds comprising sulfated nonulonic acid having antiviral activity
US6541461B2 (en) 1996-05-16 2003-04-01 Nissin Food Products Co., Ltd. Compounds having antiviral activity
US6835720B2 (en) 1996-05-16 2004-12-28 Nissin Food Products Co., Ltd. Compounds having antiviral activity
US6444649B1 (en) 1998-04-10 2002-09-03 Mitsubishi Chemical Corporation Solid dispersion containing sialic acid derivative

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