MD142C2 - Procedeu de obţinere a esterului acidului apovincaminic - Google Patents
Procedeu de obţinere a esterului acidului apovincaminicInfo
- Publication number
- MD142C2 MD142C2 MD94-0159A MD940159A MD142C2 MD 142 C2 MD142 C2 MD 142C2 MD 940159 A MD940159 A MD 940159A MD 142 C2 MD142 C2 MD 142C2
- Authority
- MD
- Moldova
- Prior art keywords
- apovincaminic
- ethyl ester
- ester preparation
- etherification
- acetonitryl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 125000004494 ethyl ester group Chemical group 0.000 title abstract 2
- VHYFNPMBLIVWCW-UHFFFAOYSA-N 4-Dimethylaminopyridine Chemical compound CN(C)C1=CC=NC=C1 VHYFNPMBLIVWCW-UHFFFAOYSA-N 0.000 abstract 2
- 238000006266 etherification reaction Methods 0.000 abstract 2
- XPARNGAWWCCOIM-UHFFFAOYSA-N 2-fluoro-1,3,5-trinitrobenzene Chemical compound [O-][N+](=O)C1=CC([N+]([O-])=O)=C(F)C([N+]([O-])=O)=C1 XPARNGAWWCCOIM-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Invenţia se referă la compuşii heterociclici.Scopul invenţiei constă în majorarea randamentului produsului cu destinaţie specială şi simplificarea procesului.Sinteza este efectuată prin eterificarea acidului apovincaminic cu alcoolul etilic în mediul ace tonitrilului şi procesul se efectuează în prezenţa 2-fluor-1,3,5-treinitrobenzenului şi a 4-dimetilaminopiridinei în calitate de agent de eterificare la temperatura de cameră timp de 3-5 ore.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES549105A ES8604956A1 (es) | 1985-11-20 | 1985-11-20 | Procedimiento de obtencion del ester etilico del acido apo- vincaminico |
| SU864028528A SU1435153A3 (ru) | 1985-11-20 | 1986-11-19 | Способ получени сложного этилового эфира аповинкаминовой кислоты |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD142B1 MD142B1 (ro) | 1995-01-30 |
| MD142C2 true MD142C2 (ro) | 1995-07-31 |
Family
ID=26156125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0159A MD142C2 (ro) | 1985-11-20 | 1994-02-14 | Procedeu de obţinere a esterului acidului apovincaminic |
Country Status (3)
| Country | Link |
|---|---|
| LT (1) | LT2245B (ro) |
| LV (1) | LV5257A3 (ro) |
| MD (1) | MD142C2 (ro) |
-
1993
- 1993-06-22 LV LV930644A patent/LV5257A3/xx unknown
- 1993-08-30 LT LTRP908A patent/LT2245B/xx not_active IP Right Cessation
-
1994
- 1994-02-14 MD MD94-0159A patent/MD142C2/ro active IP Right Grant
Non-Patent Citations (2)
| Title |
|---|
| Brevet nr. 2253750, DE, Int. cl. C 07 D 471/22, 1978- * |
| Brevet nr. 2265138, DE, Int. cl. C 07 471/22, 1977; * |
Also Published As
| Publication number | Publication date |
|---|---|
| LT2245B (lt) | 1993-11-15 |
| LV5257A3 (lv) | 1993-10-10 |
| MD142B1 (ro) | 1995-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20061118 |