ES8602034A1 - Un procedimiento para preparar nuevos peptidos - Google Patents
Un procedimiento para preparar nuevos peptidosInfo
- Publication number
- ES8602034A1 ES8602034A1 ES527542A ES527542A ES8602034A1 ES 8602034 A1 ES8602034 A1 ES 8602034A1 ES 527542 A ES527542 A ES 527542A ES 527542 A ES527542 A ES 527542A ES 8602034 A1 ES8602034 A1 ES 8602034A1
- Authority
- ES
- Spain
- Prior art keywords
- cpds
- formula
- glycine
- residue
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 6
- 239000004471 Glycine Substances 0.000 abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- UQDJGEHQDNVPGU-UHFFFAOYSA-N serine phosphoethanolamine Chemical compound [NH3+]CCOP([O-])(=O)OCC([NH3+])C([O-])=O UQDJGEHQDNVPGU-UHFFFAOYSA-N 0.000 abstract 3
- QNAYBMKLOCPYGJ-UWTATZPHSA-N D-alanine Chemical compound C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 2
- QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 230000003525 myelopoietic effect Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000018199 S phase Effects 0.000 abstract 1
- 210000003995 blood forming stem cell Anatomy 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000022131 cell cycle Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940043239 cytotoxic antineoplastic drug Drugs 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000011278 mitosis Effects 0.000 abstract 1
- 238000009877 rendering Methods 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 230000001960 triggered effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C07K7/067—Hemoregulatory peptides based on sequence Glp-Glu-Asp-Cys-Lys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8233837 | 1982-11-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES527542A0 ES527542A0 (es) | 1985-11-01 |
| ES8602034A1 true ES8602034A1 (es) | 1985-11-01 |
Family
ID=10534566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES527542A Expired ES8602034A1 (es) | 1982-11-26 | 1983-11-25 | Un procedimiento para preparar nuevos peptidos |
Country Status (14)
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4575495A (en) * | 1983-05-12 | 1986-03-11 | New York Blood Center, Inc. | Synthetic antigenic peptide derived from Hepatitis B surface antigen |
| US4578217A (en) * | 1983-05-12 | 1986-03-25 | New York Blood Center, Inc. | Synthetic antigenic peptide derived from hepatitis B surface antigen |
| IT1164225B (it) * | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
| FR2551088B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1983-08-29 | 1985-12-06 | Pasteur Institut | |
| NO860752L (no) * | 1985-06-26 | 1986-12-29 | Bio Tech As | Pentapeptider med cellevekstregulerende virkning og fremgangsmaate for fremstilling derav. |
| GB8626539D0 (en) * | 1986-11-06 | 1986-12-10 | Nycomed As | Peptide compounds |
| GB8821785D0 (en) * | 1988-09-16 | 1988-10-19 | Nycomed As | Peptide compounds |
| US5620957A (en) * | 1989-07-14 | 1997-04-15 | Smithkline Beecham Corporation | Hemoregulatory peptides |
| HU206374B (en) * | 1990-09-03 | 1992-10-28 | Richter Gedeon Vegyeszet | Process for producing pentapeptide and its salts specifically inhibiting proliferation of epidermic cells, as well as pharmaceutical compositions comprising same as active ingredient |
| TW222280B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1991-11-26 | 1994-04-11 | Smithkline Beecham Corp | |
| IL104323A0 (en) * | 1992-01-10 | 1993-05-13 | Smithkline Beecham Corp | Hemoregulatory peptides |
| GB9211674D0 (en) | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| GB9211677D0 (en) | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| GB9211668D0 (en) | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| GR1001502B (el) * | 1992-11-26 | 1994-02-28 | Smithkline Beecham Corp | Αιμορυ?μιστικά πεπτίδια. |
| CN1034735C (zh) * | 1993-01-02 | 1997-04-30 | 史密丝克莱恩比彻姆公司 | 血调节肽 |
| CA2162610A1 (en) * | 1993-05-20 | 1994-12-08 | Robert N. Moore | Peptides for suppression of myeloid progenitor cell proliferation and treatment of septic shock |
| JPH09504301A (ja) * | 1993-10-29 | 1997-04-28 | スミスクライン・ビーチャム・コーポレイション | 血液調節ペプチド |
| JP2000500463A (ja) * | 1995-11-03 | 2000-01-18 | スミスクライン・ビーチャム・コーポレイション | 血液調節化合物 |
| JP2000500468A (ja) * | 1995-11-13 | 2000-01-18 | スミスクライン・ビーチャム・コーポレイション | 血液調節化合物 |
| WO1997017959A1 (en) * | 1995-11-13 | 1997-05-22 | Smithkline Beecham Corporation | Hemoregulatory compounds |
| EP0874638A4 (en) * | 1995-11-13 | 1999-07-21 | Smithkline Beecham Corp | HEMATOREGULATORS |
| US6191146B1 (en) | 1995-11-13 | 2001-02-20 | Smithkline Beecham Corporation | Hemoregulatory compounds |
| EP0861254A4 (en) * | 1995-11-13 | 2000-06-28 | Smithkline Beecham Corp | HEMATOREGULATORS |
| CN1209061A (zh) * | 1995-11-13 | 1999-02-24 | 史密丝克莱恩比彻姆公司 | 血液调节剂化合物 |
| NZ521456A (en) * | 2000-04-19 | 2004-07-30 | Schering Corp | Macrocyclic NS3-Serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3792032A (en) * | 1970-07-31 | 1974-02-12 | Farmaceutical Soc | Polypeptides related to the c-terminal heptapeptide of bombesin and alytesin |
| US4411890A (en) * | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| US3928306A (en) * | 1973-10-23 | 1975-12-23 | Eisai Co Ltd | Peptides having xenopsin-like pharmacological activity |
| US4235772A (en) * | 1978-06-21 | 1980-11-25 | Ab Kabi | Novel peptides having growth promoting activity |
| FR2465486A1 (fr) * | 1979-09-21 | 1981-03-27 | Roussel Uclaf | Nouvelle application utilisant la lh-rh ou des agonistes |
| FR2491922A1 (fr) * | 1980-10-14 | 1982-04-16 | Roussel Uclaf | Nouveaux hexapeptides, procede pour leur preparation et application comme medicaments |
-
1983
- 1983-11-24 FI FI834320A patent/FI77875C/fi not_active IP Right Cessation
- 1983-11-24 ZA ZA838780A patent/ZA838780B/xx unknown
- 1983-11-25 NZ NZ206401A patent/NZ206401A/en unknown
- 1983-11-25 JP JP58220820A patent/JPS59112953A/ja active Granted
- 1983-11-25 DK DK539483A patent/DK166392C/da not_active IP Right Cessation
- 1983-11-25 ES ES527542A patent/ES8602034A1/es not_active Expired
- 1983-11-25 DE DE8383307210T patent/DE3381282D1/de not_active Expired - Lifetime
- 1983-11-25 EP EP83307210A patent/EP0112656B1/en not_active Expired - Lifetime
- 1983-11-25 AT AT83307210T patent/ATE50693T1/de active
- 1983-11-25 IE IE2764/83A patent/IE56362B1/en not_active IP Right Cessation
- 1983-11-25 NO NO834340A patent/NO157935C/no unknown
- 1983-11-25 AU AU21697/83A patent/AU559914B2/en not_active Ceased
- 1983-11-28 US US06/555,840 patent/US4499081A/en not_active Expired - Lifetime
- 1983-11-28 CA CA000442085A patent/CA1236786A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU2169783A (en) | 1984-05-31 |
| EP0112656A3 (en) | 1985-08-21 |
| FI834320A0 (fi) | 1983-11-24 |
| NO834340L (no) | 1984-05-28 |
| DK539483D0 (da) | 1983-11-25 |
| DK539483A (da) | 1984-05-27 |
| IE832764L (en) | 1984-05-26 |
| ATE50693T1 (de) | 1990-03-15 |
| EP0112656A2 (en) | 1984-07-04 |
| DE3381282D1 (de) | 1990-04-12 |
| AU559914B2 (en) | 1987-03-26 |
| EP0112656B1 (en) | 1990-03-07 |
| US4499081A (en) | 1985-02-12 |
| ES527542A0 (es) | 1985-11-01 |
| IE56362B1 (en) | 1991-07-03 |
| DK166392C (da) | 1993-09-27 |
| NO157935C (no) | 1988-06-15 |
| JPH0364514B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1991-10-07 |
| JPS59112953A (ja) | 1984-06-29 |
| FI77875B (fi) | 1989-01-31 |
| FI77875C (fi) | 1989-05-10 |
| NZ206401A (en) | 1986-11-12 |
| FI834320L (fi) | 1984-05-27 |
| NO157935B (no) | 1988-03-07 |
| DK166392B (da) | 1993-05-10 |
| ZA838780B (en) | 1985-01-30 |
| CA1236786A (en) | 1988-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20011110 |