ES8602034A1 - Un procedimiento para preparar nuevos peptidos - Google Patents

Un procedimiento para preparar nuevos peptidos

Info

Publication number
ES8602034A1
ES8602034A1 ES527542A ES527542A ES8602034A1 ES 8602034 A1 ES8602034 A1 ES 8602034A1 ES 527542 A ES527542 A ES 527542A ES 527542 A ES527542 A ES 527542A ES 8602034 A1 ES8602034 A1 ES 8602034A1
Authority
ES
Spain
Prior art keywords
cpds
formula
glycine
residue
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES527542A
Other languages
English (en)
Other versions
ES527542A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nyegaard and Co AS
Original Assignee
Nyegaard and Co AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nyegaard and Co AS filed Critical Nyegaard and Co AS
Publication of ES8602034A1 publication Critical patent/ES8602034A1/es
Publication of ES527542A0 publication Critical patent/ES527542A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/067—Hemoregulatory peptides based on sequence Glp-Glu-Asp-Cys-Lys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE PEPTIDOS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1 REPRESENTA UN RADICAL DE GLICOCOLA O D-ALANINAS; X1 Y X2 REPRESENTAN OH O NH2; Y N VALE 0 O 1. CONSISTE EN SOMETER UN DERIVADO PROTEGIDO DEL COMPUESTO DE FORMULA (I) A UNA REACCION DE DESPROTECCION, TAL COMO HIDROLISIS ACIDA, HIDROGENOLISIS, AMONOLISIS O HIDROGENOLISIS ENZIMATICA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DEL CANCER.
ES527542A 1982-11-26 1983-11-25 Un procedimiento para preparar nuevos peptidos Granted ES527542A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8233837 1982-11-26

Publications (2)

Publication Number Publication Date
ES8602034A1 true ES8602034A1 (es) 1985-11-01
ES527542A0 ES527542A0 (es) 1985-11-01

Family

ID=10534566

Family Applications (1)

Application Number Title Priority Date Filing Date
ES527542A Granted ES527542A0 (es) 1982-11-26 1983-11-25 Un procedimiento para preparar nuevos peptidos

Country Status (14)

Country Link
US (1) US4499081A (es)
EP (1) EP0112656B1 (es)
JP (1) JPS59112953A (es)
AT (1) ATE50693T1 (es)
AU (1) AU559914B2 (es)
CA (1) CA1236786A (es)
DE (1) DE3381282D1 (es)
DK (1) DK166392C (es)
ES (1) ES527542A0 (es)
FI (1) FI77875C (es)
IE (1) IE56362B1 (es)
NO (1) NO157935C (es)
NZ (1) NZ206401A (es)
ZA (1) ZA838780B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4575495A (en) * 1983-05-12 1986-03-11 New York Blood Center, Inc. Synthetic antigenic peptide derived from Hepatitis B surface antigen
US4578217A (en) * 1983-05-12 1986-03-25 New York Blood Center, Inc. Synthetic antigenic peptide derived from hepatitis B surface antigen
IT1164225B (it) * 1983-05-13 1987-04-08 Anic Spa Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
FR2551088B1 (es) * 1983-08-29 1985-12-06 Pasteur Institut
NO860752L (no) * 1985-06-26 1986-12-29 Bio Tech As Pentapeptider med cellevekstregulerende virkning og fremgangsmaate for fremstilling derav.
GB8626539D0 (en) * 1986-11-06 1986-12-10 Nycomed As Peptide compounds
GB8821785D0 (en) * 1988-09-16 1988-10-19 Nycomed As Peptide compounds
US5620957A (en) * 1989-07-14 1997-04-15 Smithkline Beecham Corporation Hemoregulatory peptides
HU206374B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing pentapeptide and its salts specifically inhibiting proliferation of epidermic cells, as well as pharmaceutical compositions comprising same as active ingredient
TW222280B (es) * 1991-11-26 1994-04-11 Smithkline Beecham Corp
IL104323A0 (en) * 1992-01-10 1993-05-13 Smithkline Beecham Corp Hemoregulatory peptides
GB9211668D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211677D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211674D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GR1001502B (el) * 1992-11-26 1994-02-28 Smithkline Beecham Corp Αιμορυ?μιστικά πεπτίδια.
CN1034735C (zh) * 1993-01-02 1997-04-30 史密丝克莱恩比彻姆公司 血调节肽
JPH08510745A (ja) * 1993-05-20 1996-11-12 リサーチ・コーポレイション・テクノロジーズ・インコーポレイテッド 骨髄前駆体細胞増殖および敗血症ショックの処置のためのペプチド
JPH09504301A (ja) * 1993-10-29 1997-04-28 スミスクライン・ビーチャム・コーポレイション 血液調節ペプチド
WO1997018214A1 (en) * 1995-11-03 1997-05-22 Smithkline Beecham Corporation Hemoregulatory compounds
EP1021443A4 (en) * 1995-11-13 2001-02-07 Smithkline Beecham Corp HAMOREGULATIONAL CONNECTIONS
EP0874638A4 (en) * 1995-11-13 1999-07-21 Smithkline Beecham Corp HEMATOREGULATORS
US6077855A (en) * 1995-11-13 2000-06-20 Smithkline Beecham Corporation Hemoregulatory compounds
US6191146B1 (en) 1995-11-13 2001-02-20 Smithkline Beecham Corporation Hemoregulatory compounds
EP0861254A4 (en) * 1995-11-13 2000-06-28 Smithkline Beecham Corp HEMATOREGULATORS
AU711239B2 (en) * 1995-11-13 1999-10-07 Nycomed Austria Gmbh Hemoregulatory compounds
SK14952002A3 (sk) * 2000-04-19 2003-03-04 Schering Corporation Makrocyklické zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3792032A (en) * 1970-07-31 1974-02-12 Farmaceutical Soc Polypeptides related to the c-terminal heptapeptide of bombesin and alytesin
US4411890A (en) * 1981-04-14 1983-10-25 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US3928306A (en) * 1973-10-23 1975-12-23 Eisai Co Ltd Peptides having xenopsin-like pharmacological activity
US4235772A (en) * 1978-06-21 1980-11-25 Ab Kabi Novel peptides having growth promoting activity
FR2465486A1 (fr) * 1979-09-21 1981-03-27 Roussel Uclaf Nouvelle application utilisant la lh-rh ou des agonistes
FR2491922A1 (fr) * 1980-10-14 1982-04-16 Roussel Uclaf Nouveaux hexapeptides, procede pour leur preparation et application comme medicaments

Also Published As

Publication number Publication date
FI834320A (fi) 1984-05-27
NO157935B (no) 1988-03-07
EP0112656B1 (en) 1990-03-07
AU2169783A (en) 1984-05-31
IE56362B1 (en) 1991-07-03
FI834320A0 (fi) 1983-11-24
JPS59112953A (ja) 1984-06-29
AU559914B2 (en) 1987-03-26
NO834340L (no) 1984-05-28
ZA838780B (en) 1985-01-30
DE3381282D1 (de) 1990-04-12
DK539483D0 (da) 1983-11-25
FI77875B (fi) 1989-01-31
ES527542A0 (es) 1985-11-01
US4499081A (en) 1985-02-12
EP0112656A2 (en) 1984-07-04
NO157935C (no) 1988-06-15
EP0112656A3 (en) 1985-08-21
JPH0364514B2 (es) 1991-10-07
NZ206401A (en) 1986-11-12
CA1236786A (en) 1988-05-17
ATE50693T1 (de) 1990-03-15
DK166392B (da) 1993-05-10
FI77875C (fi) 1989-05-10
DK166392C (da) 1993-09-27
DK539483A (da) 1984-05-27
IE832764L (en) 1984-05-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20011110