ES8503690A1 - Procedimiento para la preparacion de sales de acidos 15, 16-metilen-17 -pregna-4, 6-dien-21-carboxilicos - Google Patents

Procedimiento para la preparacion de sales de acidos 15, 16-metilen-17 -pregna-4, 6-dien-21-carboxilicos

Info

Publication number
ES8503690A1
ES8503690A1 ES534214A ES534214A ES8503690A1 ES 8503690 A1 ES8503690 A1 ES 8503690A1 ES 534214 A ES534214 A ES 534214A ES 534214 A ES534214 A ES 534214A ES 8503690 A1 ES8503690 A1 ES 8503690A1
Authority
ES
Spain
Prior art keywords
alpha
methylene
pregna
diene
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534214A
Other languages
English (en)
Other versions
ES534214A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES8503690A1 publication Critical patent/ES8503690A1/es
Publication of ES534214A0 publication Critical patent/ES534214A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Reinforced Plastic Materials (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE SALES DE ACIDOS 15,16-METILEN-17BAB-PREGNA-4,6-DIEN-21-CARBOXILICOS.CONSISTE EN HACER REACCIONAR COMPUESTOS DE FORMULA (II) CON UN ALCALI PARA FORMAR SALES DE ACIDOS CARBOXILICOS DE FORMULA (I); SIENDO R1 Y R2, H, OTRO ENLACE CC, O UN GRUPO METILENO QUE ESTA EN POSICION 15,16 ESTA EN POSICION BAB O BBB; Y M UN METAL ALCALINO.SE UTILIZA PARA EL TRATAMIENTO DE ENFERMEDADES PROVOCADAS POR UN HIPERALDOSTERONISMO PRIMARIO O SECUNDARIO.
ES534214A 1983-07-15 1984-07-11 Procedimiento para la preparacion de sales de acidos 15, 16-metilen-17 -pregna-4, 6-dien-21-carboxilicos Granted ES534214A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3326013A DE3326013A1 (de) 1983-07-15 1983-07-15 15,16-methylen-17(alpha)-pregna-4,6-dien-21-carbonsaeuresalze, diese enthaltende pharmazeutische praeparate sowie verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
ES8503690A1 true ES8503690A1 (es) 1985-04-01
ES534214A0 ES534214A0 (es) 1985-04-01

Family

ID=6204355

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534214A Granted ES534214A0 (es) 1983-07-15 1984-07-11 Procedimiento para la preparacion de sales de acidos 15, 16-metilen-17 -pregna-4, 6-dien-21-carboxilicos

Country Status (16)

Country Link
US (1) US4542024A (es)
EP (1) EP0131899B1 (es)
JP (1) JPS6038397A (es)
AT (1) ATE31066T1 (es)
AU (1) AU572863B2 (es)
CA (1) CA1212102A (es)
CS (1) CS244691B2 (es)
DD (1) DD216469A5 (es)
DE (2) DE3326013A1 (es)
DK (1) DK325584A (es)
ES (1) ES534214A0 (es)
FI (1) FI842742A (es)
GR (1) GR81526B (es)
HU (1) HU189422B (es)
NO (1) NO157701C (es)
ZA (1) ZA845443B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4102244A1 (de) * 1991-01-24 1992-07-30 Schering Ag 14,16ss-ethano-15ss, 16(pfeil hoch)1(pfeil hoch)-cyclo-14ss-estra-1,3,5(10)-triene
PT770332E (pt) 1995-10-16 2001-11-30 Nestle Sa Sobremesa de camadas multiplas bem como processo e dispositivo para a sua preparacao
ITMI20010821A1 (it) * 2001-04-17 2002-10-17 Gienne Pharma S P A Impiego di composti derivati dallo spirolattone per inibire l'azione pro-fibrigenetica delle cellule stellate epatiche e delle cellule musco

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
DE2744255A1 (de) * 1976-10-05 1978-04-06 Ciba Geigy Ag Verfahren zur herstellung neuer steroidverbindungen mit 19-staendiger sauerstoffunktion
DE2922500A1 (de) * 1979-05-31 1980-12-04 Schering Ag 6 beta .7 beta
DE3111951A1 (de) * 1981-03-23 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS5921698A (ja) * 1982-07-22 1984-02-03 シエ−リング・アクチエンゲゼルシヤフト １７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬

Also Published As

Publication number Publication date
AU572863B2 (en) 1988-05-19
GR81526B (es) 1984-12-11
CS244691B2 (en) 1986-08-14
JPS6038397A (ja) 1985-02-27
US4542024A (en) 1985-09-17
ZA845443B (en) 1985-03-27
EP0131899B1 (de) 1987-11-25
ATE31066T1 (de) 1987-12-15
ES534214A0 (es) 1985-04-01
FI842742A (fi) 1985-01-16
DD216469A5 (de) 1984-12-12
NO157701B (no) 1988-01-25
NO157701C (no) 1988-05-04
AU3051484A (en) 1985-01-17
HU189422B (en) 1986-07-28
FI842742A0 (fi) 1984-07-09
DE3467760D1 (en) 1988-01-07
DK325584D0 (da) 1984-07-03
EP0131899A2 (de) 1985-01-23
CA1212102A (en) 1986-09-30
DE3326013A1 (de) 1985-01-24
DK325584A (da) 1985-01-16
NO842887L (no) 1985-01-16
HUT34514A (en) 1985-03-28
EP0131899A3 (en) 1985-08-21

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