ES8304974A1 - "procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina". - Google Patents
"procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina".Info
- Publication number
- ES8304974A1 ES8304974A1 ES513102A ES513102A ES8304974A1 ES 8304974 A1 ES8304974 A1 ES 8304974A1 ES 513102 A ES513102 A ES 513102A ES 513102 A ES513102 A ES 513102A ES 8304974 A1 ES8304974 A1 ES 8304974A1
- Authority
- ES
- Spain
- Prior art keywords
- oxacyclyl
- preparation
- pharmaceutical preparations
- preparations containing
- alkylpiperidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE N-OXACICLIL-ALCOHILPIPERIDINA, DE FORMULA GENERAL (I), EN LA QUE N SIGNIFICA 1, 2 O 3; P Y Q SIGNIFICAN 1, 2 O 3; PH SIFNIFICA 1,2-FENILENO NO SUSTITUIDO; R Y R SIGNIFICAN HIDROGENO O ALCOHILO; R Y R SIGNIFICAN HIDROGENO, FENILO O ALCOHILO; X SIGNIFICA OXIGENO O AZUFRE; E Y SIGNIFICA OXIGENO O AZUFRE, Y DE SUS SALES FISIOLOGICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), CON UN COMPUESTO DE FORMULA (III), EN LAS QUE P, Q, N, PH, R , R , R , R , R , X E Y TIENEN LOS SIGNIFICADOS YA INDICADOS; Y Z ES UN HALOGENO O UN GRUPO ESTER REACTIVO. DE APLICACION EN PREPARADOS FARMACEUTICOS POR SUS EFECTOS ANTIPSICOTICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813124366 DE3124366A1 (de) | 1981-06-20 | 1981-06-20 | N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8304974A1 true ES8304974A1 (es) | 1983-03-16 |
ES513102A0 ES513102A0 (es) | 1983-03-16 |
Family
ID=6135055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES513102A Granted ES513102A0 (es) | 1981-06-20 | 1982-06-15 | "procedimiento para la preparacion de derivados de n-oxaciclil-alcohilpiperidina". |
Country Status (20)
Country | Link |
---|---|
US (1) | US4470989A (es) |
EP (1) | EP0068261B1 (es) |
JP (1) | JPS58977A (es) |
KR (1) | KR840000540A (es) |
AT (1) | ATE12498T1 (es) |
AU (1) | AU551182B2 (es) |
CA (1) | CA1175432A (es) |
DE (2) | DE3124366A1 (es) |
DK (1) | DK275782A (es) |
ES (1) | ES513102A0 (es) |
FI (1) | FI822178L (es) |
GR (1) | GR76502B (es) |
HU (1) | HU190989B (es) |
IE (1) | IE53127B1 (es) |
IL (1) | IL66084A (es) |
NO (1) | NO822041L (es) |
NZ (1) | NZ201006A (es) |
PH (1) | PH18536A (es) |
PT (1) | PT75070B (es) |
ZA (1) | ZA824328B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0101919B1 (en) * | 1982-08-05 | 1986-09-24 | Kabushiki Kaisha Toshiba | Color picture tube and method for manufacturing the same |
US5312840A (en) * | 1986-07-10 | 1994-05-17 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education | Substituted guanidines having high binding to the sigma receptor and the use thereof |
US5182292A (en) * | 1991-06-21 | 1993-01-26 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
US5212170A (en) * | 1991-06-21 | 1993-05-18 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
US5221745A (en) * | 1991-06-21 | 1993-06-22 | American Home Products Corp. | Psychotropic piperidinylmethyl benzodioxans |
DE4140540A1 (de) * | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
US6096763A (en) * | 1995-02-23 | 2000-08-01 | Merck & Co., Inc. | α1a adrenergic receptor antagonists |
US5952351A (en) * | 1995-02-23 | 1999-09-14 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
GB9603457D0 (es) * | 1996-02-19 | 1996-04-17 | Merck & Co Inc | |
US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
US6756389B2 (en) | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
AU773773B2 (en) | 1999-06-02 | 2004-06-03 | Janssen Pharmaceutica N.V. | Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives |
KR100702526B1 (ko) * | 1999-06-02 | 2007-04-04 | 얀센 파마슈티카 엔.브이. | 피롤리디닐, 피페리디닐 또는 호모피페리디닐 치환된(벤조디옥산, 벤조푸란 또는 벤조피란) 유도체 |
JO2654B1 (en) * | 2000-09-04 | 2012-06-17 | شركة جانسين فارماسوتيكا ان. في | Multiple aryl caroxa amides are useful as lipid - lowering agents |
JO2409B1 (en) * | 2000-11-21 | 2007-06-17 | شركة جانسين فارماسوتيكا ان. في | Second-phenyl carboxy amides are useful as lipid-lowering agents |
CA2465328C (en) * | 2001-11-01 | 2011-06-14 | Michael Francis Gross | Piperidines |
US8288413B2 (en) | 2005-09-30 | 2012-10-16 | Glaxo Group Limited | Benzimidazolones which have activity at M1 receptor |
MY148504A (en) | 2005-09-30 | 2013-04-30 | Glaxo Group Ltd | Compounds which have activity at m? receptor and their uses in medicine |
US8288412B2 (en) | 2005-09-30 | 2012-10-16 | Glaxo Group Limited | Compounds which have activity at M1 receptor and their uses in medicine |
GB0605784D0 (en) * | 2006-03-22 | 2006-05-03 | Glaxo Group Ltd | Compounds |
GB0718415D0 (en) | 2007-09-20 | 2007-10-31 | Glaxo Group Ltd | Compounds |
JP2010539217A (ja) | 2007-09-20 | 2010-12-16 | グラクソ グループ リミテッド | M1受容体にて活性を有する化合物および医薬としてのそれらの使用 |
CN108358832A (zh) * | 2017-12-29 | 2018-08-03 | 上海艾康睿医药科技有限公司 | 一种合成4-[(2-氨基-4-氯)苯基]-氨基-n-哌啶甲酸乙酯的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3910930A (en) * | 1973-01-04 | 1975-10-07 | Janssen Pharmaceutica Nv | 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones |
US4066772A (en) * | 1975-07-21 | 1978-01-03 | Janssen Pharmaceutica N.V. | 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds |
GR71865B (es) * | 1978-03-20 | 1983-07-07 | Ciba Geigy | |
US4181802A (en) * | 1978-05-11 | 1980-01-01 | Janssen Pharmaceutica N.V. | 1-(Heterocyclylalkyl)-1,3-dihydro-2-H-benzimidazole-2-ones |
US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
-
1981
- 1981-06-20 DE DE19813124366 patent/DE3124366A1/de not_active Withdrawn
-
1982
- 1982-06-14 AT AT82105174T patent/ATE12498T1/de active
- 1982-06-14 EP EP82105174A patent/EP0068261B1/de not_active Expired
- 1982-06-14 DE DE8282105174T patent/DE3262861D1/de not_active Expired
- 1982-06-15 ES ES513102A patent/ES513102A0/es active Granted
- 1982-06-17 PT PT75070A patent/PT75070B/pt unknown
- 1982-06-17 FI FI822178A patent/FI822178L/fi not_active Application Discontinuation
- 1982-06-18 KR KR1019820002715A patent/KR840000540A/ko unknown
- 1982-06-18 NZ NZ201006A patent/NZ201006A/en unknown
- 1982-06-18 NO NO822041A patent/NO822041L/no unknown
- 1982-06-18 AU AU84992/82A patent/AU551182B2/en not_active Ceased
- 1982-06-18 US US06/389,677 patent/US4470989A/en not_active Expired - Fee Related
- 1982-06-18 PH PH27449A patent/PH18536A/en unknown
- 1982-06-18 CA CA000405525A patent/CA1175432A/en not_active Expired
- 1982-06-18 IE IE1448/82A patent/IE53127B1/en unknown
- 1982-06-18 JP JP57104048A patent/JPS58977A/ja active Pending
- 1982-06-18 IL IL66084A patent/IL66084A/xx unknown
- 1982-06-18 ZA ZA824328A patent/ZA824328B/xx unknown
- 1982-06-18 HU HU821992A patent/HU190989B/hu unknown
- 1982-06-18 DK DK275782A patent/DK275782A/da not_active Application Discontinuation
- 1982-06-18 GR GR68474A patent/GR76502B/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI822178A0 (fi) | 1982-06-17 |
IE821448L (en) | 1982-12-20 |
DE3124366A1 (de) | 1982-12-30 |
PT75070B (de) | 1985-01-07 |
ES513102A0 (es) | 1983-03-16 |
ZA824328B (en) | 1983-04-27 |
US4470989A (en) | 1984-09-11 |
CA1175432A (en) | 1984-10-02 |
NO822041L (no) | 1982-12-21 |
NZ201006A (en) | 1985-12-13 |
ATE12498T1 (de) | 1985-04-15 |
PT75070A (de) | 1982-07-01 |
HU190989B (en) | 1986-12-28 |
GR76502B (es) | 1984-08-10 |
IE53127B1 (en) | 1988-07-06 |
PH18536A (en) | 1985-08-09 |
KR840000540A (ko) | 1984-02-25 |
AU8499282A (en) | 1983-01-06 |
IL66084A (en) | 1986-07-31 |
DE3262861D1 (en) | 1985-05-09 |
EP0068261B1 (de) | 1985-04-03 |
IL66084A0 (en) | 1982-09-30 |
DK275782A (da) | 1982-12-21 |
EP0068261A1 (de) | 1983-01-05 |
FI822178L (fi) | 1982-12-21 |
JPS58977A (ja) | 1983-01-06 |
AU551182B2 (en) | 1986-04-17 |
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