IL66084A - 1-(benzo-1,4 dioxan-2-yl)methyl)-4-(benzoimidazol-2-on-1-yl)piperidine derivatives,process for their preparation and pharmaceutical compositions containing them - Google Patents

1-(benzo-1,4 dioxan-2-yl)methyl)-4-(benzoimidazol-2-on-1-yl)piperidine derivatives,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL66084A
IL66084A IL66084A IL6608482A IL66084A IL 66084 A IL66084 A IL 66084A IL 66084 A IL66084 A IL 66084A IL 6608482 A IL6608482 A IL 6608482A IL 66084 A IL66084 A IL 66084A
Authority
IL
Israel
Prior art keywords
benzoimidazol
dioxan
benzo
methyl
preparation
Prior art date
Application number
IL66084A
Other languages
English (en)
Other versions
IL66084A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL66084A0 publication Critical patent/IL66084A0/xx
Publication of IL66084A publication Critical patent/IL66084A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL66084A 1981-06-20 1982-06-18 1-(benzo-1,4 dioxan-2-yl)methyl)-4-(benzoimidazol-2-on-1-yl)piperidine derivatives,process for their preparation and pharmaceutical compositions containing them IL66084A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813124366 DE3124366A1 (de) 1981-06-20 1981-06-20 N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung

Publications (2)

Publication Number Publication Date
IL66084A0 IL66084A0 (en) 1982-09-30
IL66084A true IL66084A (en) 1986-07-31

Family

ID=6135055

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66084A IL66084A (en) 1981-06-20 1982-06-18 1-(benzo-1,4 dioxan-2-yl)methyl)-4-(benzoimidazol-2-on-1-yl)piperidine derivatives,process for their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US4470989A (es)
EP (1) EP0068261B1 (es)
JP (1) JPS58977A (es)
KR (1) KR840000540A (es)
AT (1) ATE12498T1 (es)
AU (1) AU551182B2 (es)
CA (1) CA1175432A (es)
DE (2) DE3124366A1 (es)
DK (1) DK275782A (es)
ES (1) ES8304974A1 (es)
FI (1) FI822178L (es)
GR (1) GR76502B (es)
HU (1) HU190989B (es)
IE (1) IE53127B1 (es)
IL (1) IL66084A (es)
NO (1) NO822041L (es)
NZ (1) NZ201006A (es)
PH (1) PH18536A (es)
PT (1) PT75070B (es)
ZA (1) ZA824328B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3366460D1 (en) * 1982-08-05 1986-10-30 Toshiba Kk Color picture tube and method for manufacturing the same
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5212170A (en) * 1991-06-21 1993-05-18 American Home Products Corporation Psychotropic piperidinylmethyl benzodioxans
US5221745A (en) * 1991-06-21 1993-06-22 American Home Products Corp. Psychotropic piperidinylmethyl benzodioxans
US5182292A (en) * 1991-06-21 1993-01-26 American Home Products Corporation Psychotropic piperidinylmethyl benzodioxans
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
GB9603457D0 (es) * 1996-02-19 1996-04-17 Merck & Co Inc
US5952351A (en) * 1995-02-23 1999-09-14 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
US6096763A (en) * 1995-02-23 2000-08-01 Merck & Co., Inc. α1a adrenergic receptor antagonists
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
ES2231189T3 (es) * 1999-06-02 2005-05-16 Janssen Pharmaceutica N.V. Derivados de benzodioxano o benzopirano sustituidos con pirrolidinilo, piperidinilo u homopiperidinilo.
ES2212774T3 (es) 1999-06-02 2004-08-01 Janssen Pharmaceutica N.V. Derivados (benzodioxanicos, benzofuranicos o benzopiranicos) sustituidos con aminoalquilo.
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) * 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
WO2003037890A2 (en) * 2001-11-01 2003-05-08 Icagen, Inc. Piperidines
US8288412B2 (en) 2005-09-30 2012-10-16 Glaxo Group Limited Compounds which have activity at M1 receptor and their uses in medicine
EP1937670A1 (en) 2005-09-30 2008-07-02 Glaxo Group Limited Benzimidazolones which have activity at m1 receptor
DE602006019119D1 (de) 2005-09-30 2011-02-03 Glaxo Group Ltd Verbindungen mit aktivität am m1-rezeptor und ihre verwendung in der medizin
GB0605784D0 (en) * 2006-03-22 2006-05-03 Glaxo Group Ltd Compounds
GB0718415D0 (en) 2007-09-20 2007-10-31 Glaxo Group Ltd Compounds
EP2194982A1 (en) 2007-09-20 2010-06-16 Glaxo Group Limited Compounds which have activity at m1 receptor and their uses in medicine
CN108358832A (zh) * 2017-12-29 2018-08-03 上海艾康睿医药科技有限公司 一种合成4-[(2-氨基-4-氯)苯基]-氨基-n-哌啶甲酸乙酯的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US4066772A (en) * 1975-07-21 1978-01-03 Janssen Pharmaceutica N.V. 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
GR71865B (es) * 1978-03-20 1983-07-07 Ciba Geigy
US4181802A (en) * 1978-05-11 1980-01-01 Janssen Pharmaceutica N.V. 1-(Heterocyclylalkyl)-1,3-dihydro-2-H-benzimidazole-2-ones
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants

Also Published As

Publication number Publication date
ES513102A0 (es) 1983-03-16
ES8304974A1 (es) 1983-03-16
IE53127B1 (en) 1988-07-06
PT75070B (de) 1985-01-07
GR76502B (es) 1984-08-10
HU190989B (en) 1986-12-28
CA1175432A (en) 1984-10-02
ZA824328B (en) 1983-04-27
PT75070A (de) 1982-07-01
NZ201006A (en) 1985-12-13
EP0068261A1 (de) 1983-01-05
PH18536A (en) 1985-08-09
NO822041L (no) 1982-12-21
DE3262861D1 (en) 1985-05-09
JPS58977A (ja) 1983-01-06
AU8499282A (en) 1983-01-06
ATE12498T1 (de) 1985-04-15
AU551182B2 (en) 1986-04-17
FI822178L (fi) 1982-12-21
DK275782A (da) 1982-12-21
IE821448L (en) 1982-12-20
US4470989A (en) 1984-09-11
IL66084A0 (en) 1982-09-30
KR840000540A (ko) 1984-02-25
DE3124366A1 (de) 1982-12-30
FI822178A0 (fi) 1982-06-17
EP0068261B1 (de) 1985-04-03

Similar Documents

Publication Publication Date Title
IL66084A (en) 1-(benzo-1,4 dioxan-2-yl)methyl)-4-(benzoimidazol-2-on-1-yl)piperidine derivatives,process for their preparation and pharmaceutical compositions containing them
AU645709B2 (en) New 2,4-thiazolidinedione compounds, process for preparing them and pharmaceutical compositions containing them
IL56369A (en) Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them
NL980012I1 (nl) Mometasonfuroaat-monohydraat, werkwijze om zulks te bereiden en farmaceutische samenstellingen.
ATE104271T1 (de) 2-(2-hydroxy-3phenoxypropylamino)ethylphenoxyacetamide, verfahren und zwischenprodukte zu deren herstellung.
ATE51620T1 (de) 3-(4-piperidinyl)-1,2-benzisothiazole und deren derivate, verfahren zu ihrer herstellung und verwendung als arzneimittel.
FI823860A0 (fi) 3-(1-substituerade-4-piperidyl)-1,2-bensisoxazoler, en process foer framstaellning daerav, en farmaceutisk komposition innehaollande dessa och deras anvaendning som laekemedel
ZA925783B (en) 5-Isoquinolinesulfonamides, process for preparing them and pharmaceutical compositions containing them.
DK0614362T5 (da) Farmaceutiske præparater på basis af ebastin eller dermed analoge forbindelser
PT76037A (en) Process for preparing 2-<<4-<(4,4)dialkyl-2,6-piperidinedion-1-yl)-butyl>-1-piperazinyl>>-pyridines and pharmaceutical compositions containing them
MA22495A1 (fr) Derives d'amidinophenylalanine, procede pour leur preparation et leur utilisation
DE3775319D1 (de) Imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
IL96636A0 (en) Piperidine derivatives and pharmaceutical compositions containing them
FR2728901B1 (fr) Derives de phenyl-4-thiazoles substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
IL51974A (en) 1-(2,3-dihydro-1,4-benzodioxin-2-yl)2-(4((1h)-indol-3-yl)-piperidino)ethanol derivatives, process for preparing them and pharmaceutical compositions containing them
LTIP911A (en) Indenoindole compounds i,process for preparing thereof,pharmaceutical compositions containing this compounds,and their use
ES8103081A1 (es) Procedimiento para la obtencion de diazatriciclos
ES8100015A1 (es) Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina.
DE3381892D1 (de) 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
DE59004292D1 (de) Renin-hemmende Aminooligohydroxy-Derivate.
PT70107A (fr) Procede de preparation de nouveaux derives de 1,3-benzoxazine-2,4-dione et des compositions pharmaceutiques les contenant
DE3860117D1 (de) 2,3-dihydro-3-phenyl-benzofuran-2-on-acetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
DE2962118D1 (en) Derivatives of 1,3-dihydro-3-(1-(2-(2,3-dihydro-1,4-benzodioxin-2-yl)2-hydroxyethyl)piperidin-4-yl)2h-indol-2-on, process for their preparation, their use as medicaments and pharmaceutical compositions containing them