ES8201957A1 - Un procedimiento para producir un precursor de insulina - Google Patents
Un procedimiento para producir un precursor de insulinaInfo
- Publication number
- ES8201957A1 ES8201957A1 ES500747A ES500747A ES8201957A1 ES 8201957 A1 ES8201957 A1 ES 8201957A1 ES 500747 A ES500747 A ES 500747A ES 500747 A ES500747 A ES 500747A ES 8201957 A1 ES8201957 A1 ES 8201957A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- insulin
- formula
- amino
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13438980A | 1980-03-27 | 1980-03-27 | |
| US21069680A | 1980-11-28 | 1980-11-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES500747A0 ES500747A0 (es) | 1982-01-16 |
| ES8201957A1 true ES8201957A1 (es) | 1982-01-16 |
Family
ID=26832281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES500747A Expired ES8201957A1 (es) | 1980-03-27 | 1981-03-26 | Un procedimiento para producir un precursor de insulina |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0037255B2 (forum.php) |
| KR (1) | KR840000946B1 (forum.php) |
| AR (1) | AR224933A1 (forum.php) |
| AU (1) | AU540644B2 (forum.php) |
| CA (1) | CA1154435A (forum.php) |
| DD (1) | DD157612A5 (forum.php) |
| DE (1) | DE3161475D1 (forum.php) |
| DK (1) | DK149863C (forum.php) |
| EG (1) | EG15310A (forum.php) |
| ES (1) | ES8201957A1 (forum.php) |
| FI (1) | FI810917A7 (forum.php) |
| GB (1) | GB2073204B (forum.php) |
| GR (1) | GR73517B (forum.php) |
| HU (1) | HU185249B (forum.php) |
| IE (1) | IE51172B1 (forum.php) |
| IL (1) | IL62486A (forum.php) |
| NO (1) | NO151898C (forum.php) |
| NZ (1) | NZ196609A (forum.php) |
| PL (1) | PL127843B1 (forum.php) |
| PT (1) | PT72732B (forum.php) |
| RO (1) | RO81951B (forum.php) |
| SU (1) | SU1301319A3 (forum.php) |
| YU (1) | YU76881A (forum.php) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1983003413A1 (en) * | 1982-03-31 | 1983-10-13 | Genetics Inst | Creation of dna sequences encoding modified proinsulin precursors |
| DK58285D0 (da) * | 1984-05-30 | 1985-02-08 | Novo Industri As | Peptider samt fremstilling og anvendelse deraf |
| DE3501641A1 (de) * | 1985-01-19 | 1986-07-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen |
| DK336188D0 (da) * | 1988-06-20 | 1988-06-20 | Nordisk Gentofte | Propeptider |
| DE3901719A1 (de) * | 1989-01-21 | 1990-07-26 | Hoechst Ag | Verfahren zur herstellung eines insulinvorlaeufers |
| DE3901718A1 (de) * | 1989-01-21 | 1990-07-26 | Hoechst Ag | Verfahren zur renaturierung falscher rekombinanten von insulinvorlaeufern |
| DE59305396D1 (de) | 1992-12-02 | 1997-03-20 | Hoechst Ag | Verfahren zur Gewinnung von Proinsulin mit korrekt verbundenen Cystinbrücken |
| DE4405179A1 (de) * | 1994-02-18 | 1995-08-24 | Hoechst Ag | Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken |
| US10745457B2 (en) | 2015-09-02 | 2020-08-18 | Merck Sharp & Dohme Corp. | Process for obtaining insulin with correctly formed disulfide bonds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2253327A1 (de) * | 1972-10-31 | 1974-05-09 | Hoechst Ag | Verfahren zur herstellung von insulin, insulin-analogen und -derivaten |
-
1981
- 1981-03-24 PL PL1981230292A patent/PL127843B1/pl unknown
- 1981-03-24 CA CA000373692A patent/CA1154435A/en not_active Expired
- 1981-03-24 RO RO103808A patent/RO81951B/ro unknown
- 1981-03-24 YU YU00768/81A patent/YU76881A/xx unknown
- 1981-03-24 NZ NZ196609A patent/NZ196609A/en unknown
- 1981-03-25 PT PT72732A patent/PT72732B/pt unknown
- 1981-03-25 AU AU68719/81A patent/AU540644B2/en not_active Expired
- 1981-03-25 IL IL62486A patent/IL62486A/xx not_active IP Right Cessation
- 1981-03-25 FI FI810917A patent/FI810917A7/fi not_active Application Discontinuation
- 1981-03-25 EG EG162/81A patent/EG15310A/xx active
- 1981-03-26 IE IE679/81A patent/IE51172B1/en not_active IP Right Cessation
- 1981-03-26 ES ES500747A patent/ES8201957A1/es not_active Expired
- 1981-03-26 KR KR1019810000989A patent/KR840000946B1/ko not_active Expired
- 1981-03-26 GB GB8109543A patent/GB2073204B/en not_active Expired
- 1981-03-26 EP EP81301305A patent/EP0037255B2/en not_active Expired
- 1981-03-26 DD DD81228622A patent/DD157612A5/de unknown
- 1981-03-26 DK DK136481A patent/DK149863C/da not_active IP Right Cessation
- 1981-03-26 DE DE8181301305T patent/DE3161475D1/de not_active Expired
- 1981-03-26 GR GR64490A patent/GR73517B/el unknown
- 1981-03-26 NO NO811039A patent/NO151898C/no not_active IP Right Cessation
- 1981-03-26 SU SU813264049A patent/SU1301319A3/ru active
- 1981-03-26 HU HU81770A patent/HU185249B/hu unknown
- 1981-03-27 AR AR284771A patent/AR224933A1/es active
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