PT72732B - Process for preparing an insulin precursor - Google Patents

Process for preparing an insulin precursor

Info

Publication number
PT72732B
PT72732B PT72732A PT7273281A PT72732B PT 72732 B PT72732 B PT 72732B PT 72732 A PT72732 A PT 72732A PT 7273281 A PT7273281 A PT 7273281A PT 72732 B PT72732 B PT 72732B
Authority
PT
Portugal
Prior art keywords
preparing
insulin precursor
insulin
precursor
Prior art date
Application number
PT72732A
Other languages
English (en)
Other versions
PT72732A (en
Inventor
Bruce Hill Frank
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26832281&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT72732(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT72732A publication Critical patent/PT72732A/pt
Publication of PT72732B publication Critical patent/PT72732B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT72732A 1980-03-27 1981-03-25 Process for preparing an insulin precursor PT72732B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13438980A 1980-03-27 1980-03-27
US21069680A 1980-11-28 1980-11-28

Publications (2)

Publication Number Publication Date
PT72732A PT72732A (en) 1981-04-01
PT72732B true PT72732B (en) 1982-03-23

Family

ID=26832281

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72732A PT72732B (en) 1980-03-27 1981-03-25 Process for preparing an insulin precursor

Country Status (23)

Country Link
EP (1) EP0037255B2 (pt)
KR (1) KR840000946B1 (pt)
AR (1) AR224933A1 (pt)
AU (1) AU540644B2 (pt)
CA (1) CA1154435A (pt)
DD (1) DD157612A5 (pt)
DE (1) DE3161475D1 (pt)
DK (1) DK149863C (pt)
EG (1) EG15310A (pt)
ES (1) ES8201957A1 (pt)
FI (1) FI810917L (pt)
GB (1) GB2073204B (pt)
GR (1) GR73517B (pt)
HU (1) HU185249B (pt)
IE (1) IE51172B1 (pt)
IL (1) IL62486A (pt)
NO (1) NO151898C (pt)
NZ (1) NZ196609A (pt)
PL (1) PL127843B1 (pt)
PT (1) PT72732B (pt)
RO (1) RO81951B (pt)
SU (1) SU1301319A3 (pt)
YU (1) YU76881A (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58183659A (ja) * 1982-03-31 1983-10-26 ジェネテイックス、インスチチュ−ト、インコ−ポレ−テッド 修飾プロインシュリン前駆体、これを暗号化するｄｎａ配列およびそれらの産生方法
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
DE3501641A1 (de) * 1985-01-19 1986-07-24 Hoechst Ag, 6230 Frankfurt Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3901719A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur herstellung eines insulinvorlaeufers
DE3901718A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur renaturierung falscher rekombinanten von insulinvorlaeufern
DK0600372T3 (da) 1992-12-02 1997-08-11 Hoechst Ag Fremgangsmåde til fremstilling af proinsulin med korrekt forbundne cystinbroer.
DE4405179A1 (de) * 1994-02-18 1995-08-24 Hoechst Ag Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken
US10745457B2 (en) 2015-09-02 2020-08-18 Merck Sharp & Dohme Corp. Process for obtaining insulin with correctly formed disulfide bonds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2253327A1 (de) * 1972-10-31 1974-05-09 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten

Also Published As

Publication number Publication date
ES500747A0 (es) 1982-01-16
RO81951B (ro) 1984-02-28
YU76881A (en) 1984-04-30
FI810917L (fi) 1981-09-28
NZ196609A (en) 1984-02-03
DK149863B (da) 1986-10-13
IE810679L (en) 1981-09-27
PL127843B1 (en) 1983-11-30
EG15310A (en) 1985-12-31
KR840000946B1 (ko) 1984-07-01
DE3161475D1 (en) 1983-12-29
KR830005251A (ko) 1983-08-03
AU540644B2 (en) 1984-11-29
HU185249B (en) 1984-12-28
DK136481A (da) 1981-09-28
SU1301319A3 (ru) 1987-03-30
DD157612A5 (de) 1982-11-24
GB2073204B (en) 1983-09-21
NO151898B (no) 1985-03-18
PT72732A (en) 1981-04-01
AR224933A1 (es) 1982-01-29
EP0037255B2 (en) 1989-04-05
GB2073204A (en) 1981-10-14
NO151898C (no) 1985-06-26
EP0037255A1 (en) 1981-10-07
NO811039L (no) 1981-09-28
DK149863C (da) 1987-06-01
EP0037255B1 (en) 1983-11-23
ES8201957A1 (es) 1982-01-16
RO81951A (ro) 1984-02-21
AU6871981A (en) 1981-10-01
PL230292A1 (pt) 1981-11-27
IL62486A0 (en) 1981-05-20
GR73517B (pt) 1984-03-08
IE51172B1 (en) 1986-10-29
CA1154435A (en) 1983-09-27
IL62486A (en) 1984-12-31

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