ES8201316A1 - Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides - Google Patents
Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoidesInfo
- Publication number
- ES8201316A1 ES8201316A1 ES80498048A ES498048A ES8201316A1 ES 8201316 A1 ES8201316 A1 ES 8201316A1 ES 80498048 A ES80498048 A ES 80498048A ES 498048 A ES498048 A ES 498048A ES 8201316 A1 ES8201316 A1 ES 8201316A1
- Authority
- ES
- Spain
- Prior art keywords
- biologically active
- lipoid
- preparing
- active particles
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/586—Liposomes, microcapsules or cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- External Artificial Organs (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARAR AGENTES DE UTILIDAD CLINICA A PARTIR DE SUSTANCIAS SOLUBLES EN LIPOIDES. SE MEZCLA UNA SUSTANCI FORMADORA DE PARTICULAS DE LIPOIDES QUE CONTIENE UN AGENTE DE ACTIVIDAD SUPERFICIAL DISUELTO EN ALCOHOL, O CUALQUIER OTRO DISOLVENTE ORGANICO, CON UNA DISOLUCION DE UNA SUSTANCIA BIOLOGICAMENTE ACTIVA EN AGUA O UNA DISOLUCION CON UN PH DE 2 A 10, EN UNA RELACION DE VOLUMEN DE 1: 1000 A 9: 1, AGITANDO LA MEZCLA DE REACCION DURANTE UN MINUTO, AL MENOS, Y DEJANDOLO REPOSAR DURANTE SIETE DIAS, PARA LUEGO SEPARAR LAS PARTICULAS PRECIPITADAS. TAMBIEN SE PUEDE MEZCLAR CON UNA SOLUCION ELECTROLITICA ACUOSA, SEPARANDO LAS PARTICULAS PRECIPITADAS Y SUSPENDERLAS EN AGUA O EN UNA DISOLUCION ELECTROLITICA ACUOSA CON AGITACION O SIN ELLA. SE UTILIZA PARA PREPARAR SISTEMAS PARA EXAMENES DE INMUNODIAGNOSIS <IN VITRO>, COMO DIAGNOSTICO DE UNA DETERMINACION CUANTITATIVA DE ARTRITIS REUMATOIDE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU79HU299A HU184141B (en) | 1979-12-27 | 1979-12-27 | Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8201316A1 true ES8201316A1 (es) | 1981-12-16 |
ES498048A0 ES498048A0 (es) | 1981-12-16 |
Family
ID=10997378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES498048A Granted ES498048A0 (es) | 1979-12-27 | 1980-12-22 | Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides |
Country Status (21)
Country | Link |
---|---|
US (1) | US4396630A (es) |
JP (1) | JPS57112334A (es) |
BE (1) | BE886884A (es) |
CA (1) | CA1165237A (es) |
CH (1) | CH655246A5 (es) |
CS (1) | CS241478B2 (es) |
DD (1) | DD158738A5 (es) |
DE (1) | DE3048815A1 (es) |
DK (1) | DK160288C (es) |
ES (1) | ES498048A0 (es) |
FR (1) | FR2472386B1 (es) |
GB (1) | GB2066203B (es) |
HU (1) | HU184141B (es) |
IT (1) | IT1150073B (es) |
NL (1) | NL8007041A (es) |
PL (1) | PL228755A1 (es) |
PT (1) | PT72261B (es) |
RO (1) | RO81371A (es) |
SE (1) | SE453537B (es) |
SU (1) | SU1487802A3 (es) |
YU (1) | YU44413B (es) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4598051A (en) * | 1980-03-12 | 1986-07-01 | The Regents Of The University Of California | Liposome conjugates and diagnostic methods therewith |
US4806466A (en) * | 1981-10-29 | 1989-02-21 | The Regents Of The University Of California | Cell agglutination reagent comprising conjugates of antibody covalently bound to liposomes |
FR2521565B1 (fr) * | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
DD247570A3 (de) * | 1983-01-14 | 1987-07-15 | Univ Berlin Humboldt | Vesikulaeres trenn-, fuell- und traegermaterial |
US4515736A (en) * | 1983-05-12 | 1985-05-07 | The Regents Of The University Of California | Method for encapsulating materials into liposomes |
US5059591B1 (en) * | 1983-05-26 | 2000-04-25 | Liposome Co Inc | Drug preparations of reduced toxicity |
US4708861A (en) * | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
US6090406A (en) * | 1984-04-12 | 2000-07-18 | The Liposome Company, Inc. | Potentiation of immune responses with liposomal adjuvants |
US5916588A (en) * | 1984-04-12 | 1999-06-29 | The Liposome Company, Inc. | Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use |
GB2160312B (en) * | 1984-04-13 | 1987-09-16 | South African Inventions | Adjuvant for immunisation |
PT78628B (en) * | 1984-05-02 | 1986-06-18 | Liposome Co Inc | Pharmaceutical composition with reduced toxicity |
US4619904A (en) * | 1984-10-29 | 1986-10-28 | General Electric Company | Agglutinating immunoassay using protein-coated liquid droplets |
US4857319A (en) * | 1985-01-11 | 1989-08-15 | The Regents Of The University Of California | Method for preserving liposomes |
US5266329A (en) * | 1985-10-31 | 1993-11-30 | Kv Pharmaceutical Company | Vaginal delivery system |
DE3584523D1 (de) * | 1985-10-31 | 1991-11-28 | Kv Pharm Co | System zum freigeben von stoffen in der vagina. |
US4790987A (en) * | 1985-11-15 | 1988-12-13 | Research Corporation | Viral glycoprotein subunit vaccine |
CA1338736C (fr) * | 1986-12-05 | 1996-11-26 | Roger Baurain | Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation |
US5688519A (en) * | 1987-04-06 | 1997-11-18 | Leonard; Robert J. | Flash-flow fused medicinal implants |
US4748024A (en) * | 1987-04-06 | 1988-05-31 | Endocon, Inc. | Flash flow fused medicinal implants |
WO1990001948A1 (en) * | 1988-08-25 | 1990-03-08 | The Liposome Company, Inc. | Influenza vaccine and novel adjuvants |
ATE118096T1 (de) * | 1988-12-22 | 1995-02-15 | Baxter Diagnostics Inc | Lipohaptene und verwendung trägergebundener lipohaptene im immuntest. |
US5100662A (en) * | 1989-08-23 | 1992-03-31 | The Liposome Company, Inc. | Steroidal liposomes exhibiting enhanced stability |
JPH07113641B2 (ja) * | 1989-11-17 | 1995-12-06 | 積水化学工業株式会社 | 梅毒診断試薬の製造方法 |
NL9000207A (es) * | 1990-01-29 | 1991-08-16 | Duphar Int Res | |
US5709879A (en) * | 1990-06-29 | 1998-01-20 | Chiron Corporation | Vaccine compositions containing liposomes |
AU654824B2 (en) * | 1990-06-29 | 1994-11-24 | Chiron Corporation | Vaccine compositions containing liposomes |
IE912535A1 (en) * | 1990-07-27 | 1992-01-29 | Res Dev Foundation | Liposomes that Provide Thymic Dependent Help to Weak Vaccine¹Antigens |
WO1992004887A1 (en) * | 1990-09-25 | 1992-04-02 | Kyowa Hakko Kogyo Co., Ltd. | Induction of cytotoxic t cell |
US6048531A (en) * | 1991-04-15 | 2000-04-11 | Albany Medical College | Immunogenic composites capable of stimulating production of anti-peptide antibodies, pharmaceutical compositions employing these composites and methods of selectively inducing production of anti-peptide antibodies |
US5336507A (en) * | 1992-12-11 | 1994-08-09 | Sterling Winthrop Inc. | Use of charged phospholipids to reduce nanoparticle aggregation |
GB9320668D0 (en) | 1993-10-07 | 1993-11-24 | Secr Defence | Liposomes containing particulare materials |
AUPM500494A0 (en) * | 1994-04-12 | 1994-05-05 | Minister For Agriculture & Rural Affairs For The State Of New South Wales, The | Composition for use in increasing mucosal immunity |
KR100869824B1 (ko) * | 2000-11-09 | 2008-11-21 | 네오팜 인코포레이티드 | Sn-38 지질 복합체 및 사용 방법 |
WO2003030864A1 (en) * | 2001-05-29 | 2003-04-17 | Neopharm, Inc. | Liposomal formulation of irinotecan |
JP2005525375A (ja) * | 2002-03-05 | 2005-08-25 | トランセイブ, インク. | 生物活性物質をリポソーム又は脂質複合体内に封入する方法 |
US20060030578A1 (en) * | 2002-08-20 | 2006-02-09 | Neopharm, Inc. | Pharmaceutically active lipid based formulation of irinotecan |
WO2004035032A2 (en) * | 2002-08-20 | 2004-04-29 | Neopharm, Inc. | Pharmaceutical formulations of camptothecine derivatives |
US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
US7718189B2 (en) * | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
WO2004110346A2 (en) * | 2002-10-29 | 2004-12-23 | Transave, Inc. | Sustained release of antiinfectives |
KR100651728B1 (ko) * | 2004-11-10 | 2006-12-06 | 한국전자통신연구원 | 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법 |
JP5114628B2 (ja) * | 2005-02-25 | 2013-01-09 | 国立大学法人三重大学 | リポソームワクチンの作製法 |
PT1962805T (pt) | 2005-12-08 | 2016-10-05 | Insmed Inc | Composições de anti-infeciosos baseadas em lípidos para tratamento de infeções pulmonares |
WO2008137717A1 (en) | 2007-05-04 | 2008-11-13 | Transave, Inc. | Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof |
US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
SI2852391T1 (sl) | 2012-05-21 | 2022-04-29 | Insmed Incorporated | Sistemi za obravnavo pljučnih infekcij |
JP6529438B2 (ja) | 2012-11-29 | 2019-06-12 | インスメッド インコーポレイテッド | 安定化されたバンコマイシン処方物 |
EP3466432B1 (en) | 2014-05-15 | 2020-07-08 | Insmed Incorporated | Methods for treating pulmonary non-tuberculous mycobacterial infections |
WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3265629A (en) * | 1958-12-22 | 1966-08-09 | Ncr Co | Coating by phase separation |
DE2249552A1 (de) * | 1971-10-12 | 1973-05-30 | Inchema S A | Verfahren zur inkapsulation von insbesondere wasserloeslichen verbindungen |
GB1502774A (en) * | 1974-06-25 | 1978-03-01 | Nat Res Dev | Immunological preparations |
JPS5126213A (ja) * | 1974-08-21 | 1976-03-04 | Tanabe Seiyaku Co | Johoseibiryushiseizaino seiho |
GB1564500A (en) * | 1975-09-29 | 1980-04-10 | Wellcome Found | Biological preparations |
GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
IT1110989B (it) * | 1979-01-19 | 1986-01-13 | Erba Farmitalia | Forme farmaceutiche costitutite da liposomi e procedimenti relativi |
FR2416008A1 (fr) * | 1978-02-02 | 1979-08-31 | Oreal | Lyophilisats de liposomes |
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
JPS55118415A (en) * | 1979-02-28 | 1980-09-11 | Pii Papahadojiyopo Dometoriosu | Method of encapsulating biologically active substance in lipoid cell |
-
1979
- 1979-12-27 HU HU79HU299A patent/HU184141B/hu unknown
-
1980
- 1980-12-12 CH CH9166/80A patent/CH655246A5/de not_active IP Right Cessation
- 1980-12-19 US US06/218,126 patent/US4396630A/en not_active Expired - Fee Related
- 1980-12-22 ES ES498048A patent/ES498048A0/es active Granted
- 1980-12-22 PT PT72261A patent/PT72261B/pt unknown
- 1980-12-22 SE SE8009068A patent/SE453537B/sv not_active IP Right Cessation
- 1980-12-23 CS CS809246A patent/CS241478B2/cs unknown
- 1980-12-23 DK DK552280A patent/DK160288C/da active
- 1980-12-23 DE DE19803048815 patent/DE3048815A1/de active Granted
- 1980-12-23 PL PL22875580A patent/PL228755A1/xx unknown
- 1980-12-23 GB GB804281A patent/GB2066203B/en not_active Expired
- 1980-12-24 FR FR8027496A patent/FR2472386B1/fr not_active Expired
- 1980-12-24 CA CA000367565A patent/CA1165237A/en not_active Expired
- 1980-12-24 NL NL8007041A patent/NL8007041A/nl not_active Application Discontinuation
- 1980-12-24 IT IT26950/80A patent/IT1150073B/it active
- 1980-12-25 RO RO80102952A patent/RO81371A/ro unknown
- 1980-12-26 YU YU3290/80A patent/YU44413B/xx unknown
- 1980-12-26 JP JP55184157A patent/JPS57112334A/ja active Granted
- 1980-12-26 SU SU803220898A patent/SU1487802A3/ru active
- 1980-12-29 BE BE0/203337A patent/BE886884A/fr not_active IP Right Cessation
-
1981
- 1981-01-30 DD DD81227326A patent/DD158738A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4396630A (en) | 1983-08-02 |
CS924680A2 (en) | 1985-07-16 |
DD158738A5 (de) | 1983-02-02 |
JPH0314814B2 (es) | 1991-02-27 |
DK160288B (da) | 1991-02-25 |
SE8009068L (sv) | 1981-06-28 |
DK552280A (da) | 1981-06-28 |
CA1165237A (en) | 1984-04-10 |
CS241478B2 (en) | 1986-03-13 |
IT1150073B (it) | 1986-12-10 |
DE3048815A1 (de) | 1981-09-10 |
PL228755A1 (es) | 1982-02-15 |
YU329080A (en) | 1984-04-30 |
DK160288C (da) | 1991-08-05 |
RO81371B (ro) | 1983-11-02 |
ES498048A0 (es) | 1981-12-16 |
HU184141B (en) | 1984-07-30 |
CH655246A5 (de) | 1986-04-15 |
FR2472386A1 (es) | 1981-07-03 |
FR2472386B1 (es) | 1985-08-23 |
GB2066203A (en) | 1981-07-08 |
BE886884A (fr) | 1981-06-29 |
NL8007041A (nl) | 1981-07-16 |
PT72261B (en) | 1981-11-05 |
JPS57112334A (en) | 1982-07-13 |
SE453537B (sv) | 1988-02-08 |
SU1487802A3 (ru) | 1989-06-15 |
RO81371A (ro) | 1984-04-02 |
PT72261A (en) | 1981-01-01 |
YU44413B (en) | 1990-08-31 |
GB2066203B (en) | 1984-01-11 |
IT8026950A0 (it) | 1980-12-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8201316A1 (es) | Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides | |
AU587525B2 (en) | Indolizine derivatives, process for preparing them and the compositions containing them | |
EP0326618A4 (en) | MEDICAL COMPOSITION, WHICH CONTAINS ALBUMIN AS A CARRIER, AND METHOD FOR THE PRODUCTION THEREOF. | |
PT83509A (en) | Process for the preparation of pharmaceutical compositions with controlled release of metoprolol | |
PH21386A (en) | Platinum-diamine complexes, their pharmaceutical compositions and process for the preparation thereof | |
DE3060777D1 (en) | Drug composition based on plants and process for its preparation | |
AU646112B2 (en) | N,O-sulphated heparosans, process for preparing them and pharmaceutical compositions containing them | |
AU5642294A (en) | Bacteriocidal gas composition and process for preparing the same | |
HUT36991A (en) | Herbicide compositions containing 1-aryl-4-substituted-1,4-dihydro-5h-tetrazol-5-one /or-thione/ derivatives and process for preparing the active substances | |
DE3072004D1 (en) | N-heterocyclyl thienamycins, process for preparing and antibiotic pharmaceutical composition containing the same | |
HUT42292A (en) | Insecticidal compositions comprising fluorbenzyl esters as active substance and process for preparing the active substances | |
ES8103972A1 (es) | Un procedimiento para preparar una composicion farmaceutica que contiene fumarato de benciclano y ciclodextrina | |
EP0175667A3 (en) | Macrophage-activating composition and a process for its manufacture | |
IL56522A0 (en) | Insecticidal esters, process for preparing them and the insecticidal compositions containing them | |
ES477562A1 (es) | Procedimiento para preparar derivados de alcanolamina. | |
DE3169602D1 (en) | 2-pyridinecarboxamide derivative, process for preparing same and pharmaceutical composition, useful as an anti-allergic agent | |
HUT37857A (en) | Insectide compositions containing cyclodextrin inclusion complex as active substance and process for preparing the active substances | |
GB2050833B (en) | Pharmaceutical compositions and process for the preparation thereof | |
AU552567B2 (en) | Oligopeptides with specific inhibiting properties of collageninduced aggregation, process for preparing the same and pharmaceutical compositions containing them | |
AU540216B2 (en) | Nicotinamide derivative, process for preparing the same and pharmaceutical composition containing the same | |
ES473316A1 (es) | Procedimiento para la obtencion de 1,4-dihidropiridazinas. | |
DE3479656D1 (en) | Rhodanine derivative, process for preparing the same and pharmaceutical composition containing the same | |
DE3160797D1 (en) | 11-alpha-amino androstanes, pharmaceutical compositions containing them and processes for their preparation | |
DE3360509D1 (en) | Fluoro-ethoxyphenyl-(di)-thiophosphoric-acid esters, process for their preparation and their use as pesticides | |
EP0103265A3 (en) | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same |