ES8106554A1 - Un procedimiento para la produccion de derivados de talisomicina. - Google Patents

Un procedimiento para la produccion de derivados de talisomicina.

Info

Publication number
ES8106554A1
ES8106554A1 ES493350A ES493350A ES8106554A1 ES 8106554 A1 ES8106554 A1 ES 8106554A1 ES 493350 A ES493350 A ES 493350A ES 493350 A ES493350 A ES 493350A ES 8106554 A1 ES8106554 A1 ES 8106554A1
Authority
ES
Spain
Prior art keywords
tallysomycin
compounds
results
new
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493350A
Other languages
English (en)
Other versions
ES493350A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8106554A1 publication Critical patent/ES8106554A1/es
Publication of ES493350A0 publication Critical patent/ES493350A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE TALISOMICINA. CONSISTE EN CULTIVAR UNA CEPA PRODUCTORA DE TALIOSOMICINA DE STREPTOALLOTEICHUS HINDUSTANUS EN UN MEDIO NUTRITIVO ACUOSO Y EN PRESENCIA DE UNA AMINA PRIMARIA, O UNA SAL DE ADICION DE ACIDO ORGANCIO DE LA MISMA, HASTA QUE DICHO ORGANISMO PRODUZCA UNA CANTIDAD SUSTANCIAL DE TALISOMICINA, RECUPERANDO EL DERIVADO DE TALISOMICINA DEL MEDIO EXENTO DE SUSTANCIAS COPRODUCIDAS. EL COMPUESTO PRECURSOR DE LA AMINA ES 1,4-DIAMINOBUTANO O UNA SAL DE ADICION DE UN ACIDO INORGANICO DEL MISMO Y EL DERIVADO DE TALISOMICINA ES TALISOMICINA S10B. ACTIVIDAD ANTIMICROBIANA Y ANTITUMORAL. T
ES493350A 1979-07-13 1980-07-11 Un procedimiento para la produccion de derivados de talisomicina. Granted ES493350A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/057,528 US4246400A (en) 1979-07-13 1979-07-13 Tallysomycin compounds

Publications (2)

Publication Number Publication Date
ES8106554A1 true ES8106554A1 (es) 1981-07-01
ES493350A0 ES493350A0 (es) 1981-07-01

Family

ID=22011128

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493350A Granted ES493350A0 (es) 1979-07-13 1980-07-11 Un procedimiento para la produccion de derivados de talisomicina.

Country Status (26)

Country Link
US (1) US4246400A (es)
JP (1) JPS5659793A (es)
AU (1) AU533469B2 (es)
BE (1) BE884291A (es)
CA (1) CA1144494A (es)
CH (1) CH646982A5 (es)
CY (1) CY1317A (es)
DE (1) DE3026425A1 (es)
DK (1) DK151633C (es)
ES (1) ES493350A0 (es)
FI (1) FI67876C (es)
FR (1) FR2460961A1 (es)
GB (1) GB2053221B (es)
GR (1) GR82324B (es)
HK (1) HK8286A (es)
IE (1) IE50020B1 (es)
IL (1) IL60541A (es)
IT (1) IT1174296B (es)
LU (1) LU82612A1 (es)
MY (1) MY8800097A (es)
NL (1) NL8003970A (es)
NO (1) NO155701C (es)
NZ (1) NZ193921A (es)
SE (1) SE449751B (es)
YU (1) YU43218B (es)
ZA (1) ZA804150B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4650765A (en) * 1981-02-23 1987-03-17 American Cyanamid Company Biologically pure culture of Streptoverticillium stramineum sp. nov.
EP0058838A1 (en) * 1981-02-23 1982-09-01 American Cyanamid Company Antibiotic LL BO1208 alpha and LL BO1208 beta
JPH02267083A (ja) * 1989-04-07 1990-10-31 Nissan Motor Co Ltd 自動車のフロントボデー補強構造
US5420228A (en) * 1991-04-05 1995-05-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Fluorescent-labelled bleomycin analogues

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1038242A (en) * 1963-03-05 1966-08-10 Zaidan Hojin Biseibutsu Bleomycin and processes for preparation thereof
GB1292081A (en) * 1969-02-15 1972-10-11 Zaidan Hojin Biseibutsu Process for producing bleomycin antibiotics
US3846400A (en) * 1969-02-15 1974-11-05 Microbial Chem Res Found Novel process for producing antibiotics bleomycin
US3814796A (en) * 1969-10-09 1974-06-04 Upjohn Co Antibiotics zorbonomycin and zorbonomycin b and process for the preparation thereof
US3922262A (en) * 1971-04-28 1975-11-25 Nippon Kayaku Kk N-Substituted derivatives of bleomycins
JPS5739751B2 (es) * 1972-03-03 1982-08-23
US4051237A (en) * 1975-08-28 1977-09-27 Bristol-Myers Company Glycopeptide antibiotics bu-2231 a and b and process for producing same
US4195018A (en) * 1977-07-01 1980-03-25 Nippon Kayaku Kabushiki Kaisha 3-[(S)-1'-Phenylethylamino]propylaminobleomycin, non-toxic salt thereof, and method for producing same

Also Published As

Publication number Publication date
US4246400A (en) 1981-01-20
DK297980A (da) 1981-01-14
JPS5659793A (en) 1981-05-23
CA1144494A (en) 1983-04-12
IE801444L (en) 1981-01-13
DK151633C (da) 1988-06-20
YU43218B (en) 1989-06-30
IL60541A (en) 1983-12-30
CH646982A5 (fr) 1984-12-28
GB2053221B (en) 1983-05-05
FR2460961A1 (fr) 1981-01-30
SE449751B (sv) 1987-05-18
FR2460961B1 (es) 1983-11-18
BE884291A (fr) 1981-01-12
FI802198A (fi) 1981-01-14
HK8286A (en) 1986-02-14
CY1317A (en) 1986-03-28
NZ193921A (en) 1982-09-14
IT8049183A0 (it) 1980-07-07
DE3026425A1 (de) 1981-01-29
AU533469B2 (en) 1983-11-24
MY8800097A (en) 1988-12-31
SE8005134L (sv) 1981-01-14
YU143580A (en) 1983-04-30
DK151633B (da) 1987-12-21
NL8003970A (nl) 1981-01-15
GB2053221A (en) 1981-02-04
DE3026425C2 (es) 1989-11-09
ZA804150B (en) 1981-07-29
NO802048L (no) 1981-01-14
FI67876C (fi) 1985-06-10
IE50020B1 (en) 1986-02-05
LU82612A1 (fr) 1981-02-02
NO155701B (no) 1987-02-02
FI67876B (fi) 1985-02-28
AU5919080A (en) 1981-01-15
ES493350A0 (es) 1981-07-01
NO155701C (no) 1987-05-13
JPS6328080B2 (es) 1988-06-07
IT1174296B (it) 1987-07-01
IL60541A0 (en) 1980-09-16
GR82324B (es) 1984-12-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603