ES8106500A1 - Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleina - Google Patents
Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleinaInfo
- Publication number
- ES8106500A1 ES8106500A1 ES493503A ES493503A ES8106500A1 ES 8106500 A1 ES8106500 A1 ES 8106500A1 ES 493503 A ES493503 A ES 493503A ES 493503 A ES493503 A ES 493503A ES 8106500 A1 ES8106500 A1 ES 8106500A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- carbon atoms
- alkyl
- manufacture
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical class C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 alkyl radical Chemical class 0.000 abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- JYVKEPSEMQJPIO-UHFFFAOYSA-N 3-(6,7-dimethoxyisoquinolin-1-yl)-3-(3,4-dimethoxyphenyl)propan-1-amine Chemical compound COC=1C=C(C=CC1OC)C(CCN)C1=NC=CC2=CC(=C(C=C12)OC)OC JYVKEPSEMQJPIO-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- KHUXNRRPPZOJPT-UHFFFAOYSA-N phenoxy radical Chemical compound O=C1C=C[CH]C=C1 KHUXNRRPPZOJPT-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7925276 | 1979-07-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8106500A1 true ES8106500A1 (es) | 1981-07-01 |
| ES493503A0 ES493503A0 (es) | 1981-07-01 |
Family
ID=10506637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES493503A Granted ES493503A0 (es) | 1979-07-19 | 1980-07-18 | Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleina |
Country Status (28)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10320274A1 (de) * | 2003-05-07 | 2004-12-09 | Sennheiser Electronic Gmbh & Co. Kg | System zur ortssensitiven Wiedergabe von Audiosignalen |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1400425A (en) * | 1971-09-22 | 1975-07-16 | Rolland Sa A | Substituted 3-hydroxymethyl-isoquinolines and derivatives |
| US3966724A (en) * | 1974-12-20 | 1976-06-29 | Armour Pharmaceutical Company | 1-(α-Aminomethylbenzyl)isoquinoline compounds |
| IT1143667B (it) * | 1977-05-30 | 1986-10-22 | Scharber Per L Ind Farmaceutic | Derivato paraverolinico ad azione duratura e procedimento per ottenerlo |
| FI802117A7 (fi) * | 1979-07-19 | 1981-01-01 | Andre Buzas | Menetelmä papaveriini-karbanionin valmistamiseksi. |
-
1980
- 1980-07-02 FI FI802118A patent/FI77027C/fi not_active IP Right Cessation
- 1980-07-02 IN IN491/DEL/80A patent/IN154316B/en unknown
- 1980-07-02 ZA ZA00803993A patent/ZA803993B/xx unknown
- 1980-07-03 IL IL60482A patent/IL60482A/xx unknown
- 1980-07-08 MX MX808914U patent/MX5962E/es unknown
- 1980-07-08 CH CH520780A patent/CH644848A5/fr not_active IP Right Cessation
- 1980-07-09 BE BE0/201345A patent/BE884242A/fr not_active IP Right Cessation
- 1980-07-09 NZ NZ194280A patent/NZ194280A/xx unknown
- 1980-07-10 LU LU82608A patent/LU82608A1/fr unknown
- 1980-07-15 MA MA19105A patent/MA18906A1/fr unknown
- 1980-07-15 NL NL8004053A patent/NL8004053A/nl not_active Application Discontinuation
- 1980-07-15 GR GR62459A patent/GR69195B/el unknown
- 1980-07-17 FR FR8015780A patent/FR2461702A1/fr active Granted
- 1980-07-17 CA CA000356370A patent/CA1152998A/en not_active Expired
- 1980-07-17 AR AR281799A patent/AR228953A1/es active
- 1980-07-17 AT AT0371980A patent/AT375649B/de not_active IP Right Cessation
- 1980-07-17 FR FR8015781A patent/FR2461497A1/fr active Granted
- 1980-07-18 JP JP9765480A patent/JPS5618964A/ja active Pending
- 1980-07-18 IT IT8023536A patent/IT1237319B/it active
- 1980-07-18 SE SE8005260A patent/SE448092B/sv not_active IP Right Cessation
- 1980-07-18 PT PT71578A patent/PT71578A/pt unknown
- 1980-07-18 DK DK310180A patent/DK152124C/da not_active IP Right Cessation
- 1980-07-18 IE IE1498/80A patent/IE50023B1/en unknown
- 1980-07-18 ES ES493503A patent/ES493503A0/es active Granted
- 1980-07-18 NO NO802160A patent/NO155883C/no unknown
- 1980-07-18 AU AU60630/80A patent/AU538065B2/en not_active Ceased
- 1980-07-18 DE DE3027338A patent/DE3027338C2/de not_active Expired
- 1980-07-19 EG EG433/80A patent/EG14616A/xx active
- 1980-07-19 OA OA57177A patent/OA06696A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19960603 |