ES8105291A1 - Procedimiento para la obtencion de derivados del decahidro- quinolinol - Google Patents
Procedimiento para la obtencion de derivados del decahidro- quinolinolInfo
- Publication number
- ES8105291A1 ES8105291A1 ES495153A ES495153A ES8105291A1 ES 8105291 A1 ES8105291 A1 ES 8105291A1 ES 495153 A ES495153 A ES 495153A ES 495153 A ES495153 A ES 495153A ES 8105291 A1 ES8105291 A1 ES 8105291A1
- Authority
- ES
- Spain
- Prior art keywords
- decahydroquinolinol
- formula
- reaction
- room temperature
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 N-SUBSTITUTED DECAHYDROQUINOLINE Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- YXFVVABEGXRONW-CNRUNOGKSA-N tritiomethylbenzene Chemical compound [3H]CC1=CC=CC=C1 YXFVVABEGXRONW-CNRUNOGKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7923289A FR2465724A1 (fr) | 1979-09-19 | 1979-09-19 | Nouveaux derives de decahydroquinoleinol, leur procede de preparation ainsi que leurs applications en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES495153A0 ES495153A0 (es) | 1981-06-01 |
| ES8105291A1 true ES8105291A1 (es) | 1981-06-01 |
Family
ID=9229781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES495153A Expired ES8105291A1 (es) | 1979-09-19 | 1980-09-18 | Procedimiento para la obtencion de derivados del decahidro- quinolinol |
Country Status (37)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4425349A (en) | 1979-07-02 | 1984-01-10 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Sulfur-containing isoquinoline derivatives in pharmaceutical compositions and methods of use |
| FR2565979B1 (fr) * | 1984-06-13 | 1987-03-20 | Labaz Sanofi Nv | Nouveaux derives de decahydroquinoleinol, leur procede de preparation et les compositions les contenant |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791678A (fr) * | 1971-11-23 | 1973-05-21 | Labaz | Nouveaux derives de decahydroquinoleinol, leur procede de preparation ainsi que les compositions therapeutiques les contenant |
| US4173636A (en) * | 1975-12-16 | 1979-11-06 | Labaz | Decahydroquinolines, pharmaceutical compositions and methods of use |
-
1979
- 1979-09-19 FR FR7923289A patent/FR2465724A1/fr active Granted
-
1980
- 1980-08-19 MC MC801467A patent/MC1346A1/xx unknown
- 1980-08-21 ZA ZA00805164A patent/ZA805164B/xx unknown
- 1980-08-22 AU AU61687/80A patent/AU530427B2/en not_active Ceased
- 1980-08-25 IS IS2579A patent/IS1122B6/is unknown
- 1980-08-25 IL IL60913A patent/IL60913A/xx unknown
- 1980-08-27 IN IN985/CAL/80A patent/IN152974B/en unknown
- 1980-09-04 US US06/184,129 patent/US4332805A/en not_active Expired - Lifetime
- 1980-09-05 GR GR62820A patent/GR69823B/el unknown
- 1980-09-09 IE IE1888/80A patent/IE50790B1/en unknown
- 1980-09-10 ZW ZW208/80A patent/ZW20880A1/xx unknown
- 1980-09-11 ZM ZM78/80A patent/ZM7880A1/xx unknown
- 1980-09-11 NZ NZ194924A patent/NZ194924A/en unknown
- 1980-09-12 RO RO102150A patent/RO80663B/ro unknown
- 1980-09-15 FI FI802879A patent/FI70705C/fi not_active IP Right Cessation
- 1980-09-16 PT PT71808A patent/PT71808B/pt unknown
- 1980-09-17 AR AR282558A patent/AR224652A1/es active
- 1980-09-17 PH PH24595A patent/PH16992A/en unknown
- 1980-09-17 PL PL1980226793A patent/PL123443B1/pl unknown
- 1980-09-17 SU SU802980755A patent/SU936808A3/ru active
- 1980-09-18 ES ES495153A patent/ES8105291A1/es not_active Expired
- 1980-09-18 AT AT0467780A patent/AT375344B/de not_active IP Right Cessation
- 1980-09-18 NO NO802775A patent/NO153727C/no unknown
- 1980-09-18 DK DK395680A patent/DK149588C/da active
- 1980-09-18 CA CA000360502A patent/CA1144170A/en not_active Expired
- 1980-09-18 HU HU802295A patent/HU182204B/hu unknown
- 1980-09-18 GB GB8030202A patent/GB2061267B/en not_active Expired
- 1980-09-18 CS CS806308A patent/CS215072B2/cs unknown
- 1980-09-18 EP EP80870039A patent/EP0026168B1/fr not_active Expired
- 1980-09-18 DE DE8080870039T patent/DE3062357D1/de not_active Expired
- 1980-09-18 YU YU02396/80A patent/YU239680A/xx unknown
- 1980-09-18 BG BG049093A patent/BG31798A3/xx unknown
- 1980-09-19 OA OA57214A patent/OA06620A/xx unknown
- 1980-09-19 JP JP13144280A patent/JPS5673063A/ja active Pending
- 1980-09-19 DD DD80224021A patent/DD153118A5/de unknown
- 1980-09-19 MA MA19155A patent/MA18954A1/fr unknown
- 1980-09-20 EG EG578/80A patent/EG14833A/xx active
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