ES8103976A1 - Un metodo de producir proteinas de interferon humano de for-ma le - Google Patents

Un metodo de producir proteinas de interferon humano de for-ma le

Info

Publication number
ES8103976A1
ES8103976A1 ES490697A ES490697A ES8103976A1 ES 8103976 A1 ES8103976 A1 ES 8103976A1 ES 490697 A ES490697 A ES 490697A ES 490697 A ES490697 A ES 490697A ES 8103976 A1 ES8103976 A1 ES 8103976A1
Authority
ES
Spain
Prior art keywords
species
affinity chromatography
interferon proteins
interferon
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490697A
Other languages
English (en)
Spanish (es)
Other versions
ES490697A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfred Benzon AS
Original Assignee
Alfred Benzon AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27220922&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8103976(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfred Benzon AS filed Critical Alfred Benzon AS
Publication of ES490697A0 publication Critical patent/ES490697A0/es
Publication of ES8103976A1 publication Critical patent/ES8103976A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES490697A 1979-04-20 1980-04-18 Un metodo de producir proteinas de interferon humano de for-ma le Expired ES8103976A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK164579 1979-04-20
DK79180 1980-02-22
DK148480 1980-04-02

Publications (2)

Publication Number Publication Date
ES490697A0 ES490697A0 (es) 1981-04-16
ES8103976A1 true ES8103976A1 (es) 1981-04-16

Family

ID=27220922

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490697A Expired ES8103976A1 (es) 1979-04-20 1980-04-18 Un metodo de producir proteinas de interferon humano de for-ma le

Country Status (15)

Country Link
EP (2) EP0091543B1 (enExample)
JP (2) JPH0742317B2 (enExample)
AU (1) AU539494B2 (enExample)
CA (1) CA1168151A (enExample)
DE (2) DE3072134D1 (enExample)
ES (1) ES8103976A1 (enExample)
FI (1) FI77877C (enExample)
HK (1) HK22792A (enExample)
IE (1) IE55791B1 (enExample)
IL (1) IL59880A (enExample)
NO (1) NO165961C (enExample)
NZ (1) NZ193487A (enExample)
PT (1) PT71111A (enExample)
SG (1) SG92591G (enExample)
WO (1) WO1980002229A1 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
DE3005843A1 (de) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
DK170476B1 (da) 1980-04-03 1995-09-11 Biogen Inc Rekombinant DNA-molekyle, uni-cellulær vært transformeret med mindst ét rekombinant DNA-molekyle, fremgangsmåde til transformering af en uni-cellulær vært, samt fremgangsmåder til fremstilling af et polpeptid, der udviser den immunologiske eller biologiske aktivitet af human beta-interferon
EP0050129B1 (en) * 1980-04-11 1992-03-18 Celltech Limited Monoclonal antibody
CH651308A5 (de) * 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
FR2492842A1 (fr) * 1980-10-24 1982-04-30 Centre Nat Rech Scient Hybride cellulaire produisant un anticorps specifique de l'interferon leucocytaire humain et procede de formation d'hybrides cellulaires producteurs d'anticorps specifiques de l'interferon humain
JPS58500037A (ja) * 1980-11-07 1983-01-06 セルテク　リミテツド インタ−フェロンの検定法
EP0064063B1 (en) * 1980-11-07 1985-09-11 Celltech Limited Assay for interferon
FR2500754B1 (fr) * 1981-02-27 1986-06-27 Hoffmann La Roche Anticorps monoclonaux
DE3280127D1 (de) * 1981-03-27 1990-04-12 Ici Plc Genetisch modifizierte mikroorganismen.
IL65475A0 (en) * 1981-04-17 1982-07-30 Meloy Lab Production of immune interferon and its mrna
EP0085693A1 (en) * 1981-08-14 1983-08-17 A/S Alfred Benzon Subjects relating to human inteferon-alpha subtype proteins and corresponding antibodies
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
US6432677B1 (en) 1982-03-08 2002-08-13 Genentech, Inc. Non-human animal interferons
JPS58201794A (ja) * 1982-05-17 1983-11-24 Toray Ind Inc ヒトインターフェロンβの濃縮精製法
US4992271A (en) * 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
US5702699A (en) * 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US4534906A (en) * 1982-11-01 1985-08-13 Genentech, Inc. Removal of impurities from human leukocyte interferon preparations
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
DE3306060A1 (de) * 1983-02-22 1984-08-23 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neue immunglobulin-produzierende hybridzellinien, deren verwendung und verfahren zu deren herstellung
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
SE468251B (sv) 1989-06-20 1992-11-30 Bionative Ab Reningsprocess foer interferon
US5391713A (en) * 1989-06-20 1995-02-21 Bionative Ab Interferon purification process
US5503828A (en) * 1992-02-10 1996-04-02 Interferon Sciences, Inc. Alpha interferon composition and method for its production from human peripheral blood leukocytes
US5676942A (en) * 1992-02-10 1997-10-14 Interferon Sciences, Inc. Composition containing human alpha interferon species proteins and method for use thereof
JP4706093B2 (ja) * 2000-09-25 2011-06-22 富士レビオ株式会社 パルボウイルスの除去方法及び精製方法
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351665A1 (fr) * 1976-05-21 1977-12-16 Elf Aquitaine Procede de purification de preparations possedant notamment une activite interferon, preparations purifiees ainsi obtenues et leur application en tant que medicament
NL7703281A (nl) * 1977-03-25 1978-09-27 Stichting Rega V Z W Werkwijze voor het bereiden van interferon.
FR2389380B1 (enExample) * 1977-05-02 1980-02-29 Anvar
IN150740B (enExample) * 1978-11-24 1982-12-04 Hoffmann La Roche
IE54096B1 (en) * 1980-01-08 1989-06-21 Biogen Nv Dn sequences, recombinant dna molecules and processes for producing human interferon - like polypeptides
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain

Also Published As

Publication number Publication date
IE800796L (en) 1980-10-20
DE91543T1 (de) 1984-12-20
CA1168151A (en) 1984-05-29
PT71111A (en) 1980-05-01
EP0091543B1 (en) 1989-06-14
AU5759980A (en) 1980-10-23
EP0018218B1 (en) 1988-11-23
JPH0794480B2 (ja) 1995-10-11
SG92591G (en) 1993-02-19
NO801133L (no) 1980-12-18
NZ193487A (en) 1983-07-15
JPH0742317B2 (ja) 1995-05-10
ES490697A0 (es) 1981-04-16
IE55791B1 (en) 1991-01-16
FI77877C (fi) 1989-05-10
FI77877B (fi) 1989-01-31
IL59880A0 (en) 1980-06-30
JPS56500536A (enExample) 1981-04-23
WO1980002229A1 (en) 1980-10-30
FI801215A7 (fi) 1980-10-21
AU539494B2 (en) 1984-10-04
EP0091543A1 (en) 1983-10-19
EP0018218A1 (en) 1980-10-29
JPH02198A (ja) 1990-01-05
HK22792A (en) 1992-04-03
NO165961B (no) 1991-01-28
NO165961C (no) 1991-05-15
DE3072134D1 (en) 1988-12-29
IL59880A (en) 1984-03-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990201