NZ193487A - Purification of human le form interferon proteins and antibodies thereto - Google Patents

Purification of human le form interferon proteins and antibodies thereto

Info

Publication number
NZ193487A
NZ193487A NZ193487A NZ19348780A NZ193487A NZ 193487 A NZ193487 A NZ 193487A NZ 193487 A NZ193487 A NZ 193487A NZ 19348780 A NZ19348780 A NZ 19348780A NZ 193487 A NZ193487 A NZ 193487A
Authority
NZ
New Zealand
Prior art keywords
antibodies
purification
human
interferon proteins
form interferon
Prior art date
Application number
NZ193487A
Other languages
English (en)
Inventor
K Berg
Original Assignee
Benzon As Alfred
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27220922&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ193487(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Benzon As Alfred filed Critical Benzon As Alfred
Publication of NZ193487A publication Critical patent/NZ193487A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NZ193487A 1979-04-20 1980-04-21 Purification of human le form interferon proteins and antibodies thereto NZ193487A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK164579 1979-04-20
DK79180 1980-02-22
DK148480 1980-04-02

Publications (1)

Publication Number Publication Date
NZ193487A true NZ193487A (en) 1983-07-15

Family

ID=27220922

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ193487A NZ193487A (en) 1979-04-20 1980-04-21 Purification of human le form interferon proteins and antibodies thereto

Country Status (15)

Country Link
EP (2) EP0091543B1 (enExample)
JP (2) JPH0742317B2 (enExample)
AU (1) AU539494B2 (enExample)
CA (1) CA1168151A (enExample)
DE (2) DE3072134D1 (enExample)
ES (1) ES490697A0 (enExample)
FI (1) FI77877C (enExample)
HK (1) HK22792A (enExample)
IE (1) IE55791B1 (enExample)
IL (1) IL59880A (enExample)
NO (1) NO165961C (enExample)
NZ (1) NZ193487A (enExample)
PT (1) PT71111A (enExample)
SG (1) SG92591G (enExample)
WO (1) WO1980002229A1 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
DE3005843A1 (de) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
DE3177213D1 (de) 1980-04-03 1990-10-18 Biogen Inc Dns-sequenzen, rekombinante dns-molekuele und verfahren zur herstellung von dem menschlichen fibroblast-interferon.
GB2083836B (en) * 1980-04-11 1984-03-28 Burke Derek Clissold Monoclonal antibody
CH651308A5 (de) * 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
FR2492842A1 (fr) * 1980-10-24 1982-04-30 Centre Nat Rech Scient Hybride cellulaire produisant un anticorps specifique de l'interferon leucocytaire humain et procede de formation d'hybrides cellulaires producteurs d'anticorps specifiques de l'interferon humain
JPS58500037A (ja) * 1980-11-07 1983-01-06 セルテク　リミテツド インタ−フェロンの検定法
EP0064063B1 (en) * 1980-11-07 1985-09-11 Celltech Limited Assay for interferon
AU561649B2 (en) * 1981-02-27 1987-05-14 F. Hoffmann-La Roche Ag Antibodies to proteins
DE3280127D1 (de) * 1981-03-27 1990-04-12 Ici Plc Genetisch modifizierte mikroorganismen.
IL65475A0 (en) * 1981-04-17 1982-07-30 Meloy Lab Production of immune interferon and its mrna
EP0085693A1 (en) * 1981-08-14 1983-08-17 A/S Alfred Benzon Subjects relating to human inteferon-alpha subtype proteins and corresponding antibodies
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
US6432677B1 (en) 1982-03-08 2002-08-13 Genentech, Inc. Non-human animal interferons
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
JPS58201794A (ja) * 1982-05-17 1983-11-24 Toray Ind Inc ヒトインターフェロンβの濃縮精製法
US4992271A (en) * 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
US5702699A (en) * 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US4534906A (en) * 1982-11-01 1985-08-13 Genentech, Inc. Removal of impurities from human leukocyte interferon preparations
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
DE3306060A1 (de) * 1983-02-22 1984-08-23 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neue immunglobulin-produzierende hybridzellinien, deren verwendung und verfahren zu deren herstellung
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
SE468251B (sv) 1989-06-20 1992-11-30 Bionative Ab Reningsprocess foer interferon
US5391713A (en) * 1989-06-20 1995-02-21 Bionative Ab Interferon purification process
US5676942A (en) * 1992-02-10 1997-10-14 Interferon Sciences, Inc. Composition containing human alpha interferon species proteins and method for use thereof
RU2129437C1 (ru) * 1992-02-10 1999-04-27 Интерферон Сайнс Инк. Композиция альфа-интерферона и способ ее получения из лейкоцитов крови человека
JP4706093B2 (ja) * 2000-09-25 2011-06-22 富士レビオ株式会社 パルボウイルスの除去方法及び精製方法
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351665A1 (fr) * 1976-05-21 1977-12-16 Elf Aquitaine Procede de purification de preparations possedant notamment une activite interferon, preparations purifiees ainsi obtenues et leur application en tant que medicament
NL7703281A (nl) * 1977-03-25 1978-09-27 Stichting Rega V Z W Werkwijze voor het bereiden van interferon.
FR2389380B1 (enExample) * 1977-05-02 1980-02-29 Anvar
IN150740B (enExample) * 1978-11-24 1982-12-04 Hoffmann La Roche
CY1346A (en) * 1980-01-08 1987-01-16 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human interferon-like polypeptides
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain

Also Published As

Publication number Publication date
JPH0794480B2 (ja) 1995-10-11
SG92591G (en) 1993-02-19
EP0018218B1 (en) 1988-11-23
EP0091543A1 (en) 1983-10-19
PT71111A (en) 1980-05-01
IL59880A (en) 1984-03-30
AU539494B2 (en) 1984-10-04
NO165961C (no) 1991-05-15
ES8103976A1 (es) 1981-04-16
DE91543T1 (de) 1984-12-20
CA1168151A (en) 1984-05-29
NO801133L (no) 1980-12-18
ES490697A0 (es) 1981-04-16
FI77877C (fi) 1989-05-10
DE3072134D1 (en) 1988-12-29
EP0091543B1 (en) 1989-06-14
JPH0742317B2 (ja) 1995-05-10
AU5759980A (en) 1980-10-23
HK22792A (en) 1992-04-03
IE800796L (en) 1980-10-20
IE55791B1 (en) 1991-01-16
NO165961B (no) 1991-01-28
FI801215A7 (fi) 1980-10-21
IL59880A0 (en) 1980-06-30
FI77877B (fi) 1989-01-31
EP0018218A1 (en) 1980-10-29
JPH02198A (ja) 1990-01-05
WO1980002229A1 (en) 1980-10-30
JPS56500536A (enExample) 1981-04-23

Similar Documents

Publication Publication Date Title
DE3072134D1 (en) Interferon proteins and method of producing same
NZ192991A (en) Preparation of purified protein hydrolysate
GB2037296B (en) Purified proteins expecially interferon and process therefor
PT72322B (en) Process for preparation of recombinant dna molecules and of polipeptides similar to human interferon
DE3275923D1 (en) Conjugates of anticoagulant and protein
GB2043889B (en) Determination of protein
PT77573B (en) Human immune interferon protein and production thereof
DE2962359D1 (en) Method of purification of human fibroblast interferon
JPS539762A (en) Hydoxyysuccinimideeester derivative* its preparation and method of bonding biologically active proteins
IL88375A0 (en) Monoclonal antibodies to interferon-beta 2 and method of purification of interferon-beta 2
GB2196634B (en) Monoclonal antibodies to hiv and related peptides
JPS5697299A (en) Complex body of betaagalactosyllumbelliferoneelabelled protein and polypeptide
JPS57175126A (en) Hem iron-enhanced amino acid medicine and manufacture of same from hem protein
EP0227110A3 (en) Human immunoglobulin g fc region protein and production thereof
ZA849161B (en) Purification of cancer-associated protein and preparation of antibody thereto
GB8413675D0 (en) Preparation of protein concentrates
NO802297L (no) Homogent fibroblast-interferon og fremstilling av dette
MW783A1 (en) Homogeneous human immune interferon and process therefor
MW3379A1 (en) Purified proteins and process therefor
JPS52125165A (en) Preparation of secretin and purification thereof
EP0145373A3 (en) Purification of cancer-associated protein and preparation of antibody thereto
IL86960A0 (en) Preparation of human monoclonal antibodies
EP0205046A3 (en) Monoclonal antibody to human protein c
JPS52144700A (en) Fractionation and separation of protein
DE3276871D1 (en) Preparation of 6-deoxy-d-fructose and 6-deoxy-l-sorbose