ES529636A0 - Procedimiento para la preparacion de derivados de carbaciclina - Google Patents

Procedimiento para la preparacion de derivados de carbaciclina

Info

Publication number
ES529636A0
ES529636A0 ES529636A ES529636A ES529636A0 ES 529636 A0 ES529636 A0 ES 529636A0 ES 529636 A ES529636 A ES 529636A ES 529636 A ES529636 A ES 529636A ES 529636 A0 ES529636 A0 ES 529636A0
Authority
ES
Spain
Prior art keywords
derivatives
carbacicline
procedure
preparation
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES529636A
Other languages
English (en)
Other versions
ES8500209A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES8500209A1 publication Critical patent/ES8500209A1/es
Publication of ES529636A0 publication Critical patent/ES529636A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Basic Packing Technique (AREA)
  • Ink Jet Recording Methods And Recording Media Thereof (AREA)
  • Lubricants (AREA)
  • Medicinal Preparation (AREA)
ES529636A 1983-02-18 1984-02-10 Procedimiento para la preparacion de derivados de carbaciclina Granted ES529636A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833306123 DE3306123A1 (de) 1983-02-18 1983-02-18 Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES8500209A1 ES8500209A1 (es) 1984-11-01
ES529636A0 true ES529636A0 (es) 1984-11-01

Family

ID=6191513

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529636A Granted ES529636A0 (es) 1983-02-18 1984-02-10 Procedimiento para la preparacion de derivados de carbaciclina

Country Status (22)

Country Link
US (1) US5013758A (es)
EP (1) EP0119949B1 (es)
JP (1) JPH0611726B2 (es)
AT (1) ATE38831T1 (es)
AU (1) AU580728B2 (es)
CA (1) CA1251200A (es)
CS (1) CS270552B2 (es)
DD (1) DD216448A5 (es)
DE (2) DE3306123A1 (es)
DK (1) DK155828C (es)
ES (1) ES529636A0 (es)
FI (1) FI78065C (es)
GR (1) GR81961B (es)
HU (1) HU191994B (es)
IE (1) IE56703B1 (es)
IL (1) IL70905A (es)
NO (1) NO157060C (es)
NZ (1) NZ207061A (es)
PH (1) PH21468A (es)
SU (1) SU1384196A3 (es)
YU (1) YU45173B (es)
ZA (1) ZA841198B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3225287A1 (de) * 1982-07-02 1984-01-05 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3610556A1 (de) * 1986-03-26 1987-10-01 Schering Ag 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung
DE3727065A1 (de) * 1987-08-11 1989-02-23 Schering Ag Verfahren zur herstellung von e/z-gemischen von 2-(bicyclo-(3.3.0)-octan-3-yliden) -essigsaeurederivaten mit ueberwiegendem e- oder z-anteil
US5169960A (en) * 1987-08-11 1992-12-08 Schering Aktiengesellschaft Process for the production of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene)-acetic acid derivatives with predominant E or Z portion
US5371284A (en) * 1987-09-03 1994-12-06 Schering Corporation Phenyl acetylenic acetals
DE3835162A1 (de) * 1988-10-13 1990-04-19 Schering Ag (1s,2s,3r,5r)-2-((3s)-2-halogen-3-hydroxy-1-alken(inyl))-3-trialkylsilyloxy-7,7-(2,2-dimethyl-trimethylendioxy)-bicyclo-(3.3.0)-octan-verbindungen und verfahren zu deren herstellung
DE3909329A1 (de) * 1989-03-17 1990-09-20 Schering Ag 20-alkyl-13,14,18,18,19,19-hexadehydro-3- oxa-isocarbacyclin-derivate und ihre pharmazeutische verwendung
DE3933523A1 (de) * 1989-10-05 1991-04-11 Schering Ag Antimetastatisch wirkende mittel
GB9011588D0 (en) * 1990-05-24 1990-07-11 Wellcome Found Prostaglandin analogues for use in medicine
DE4028864A1 (de) * 1990-09-07 1992-03-12 Schering Ag Verfahren zur herstellung von e/z-mischungen von 2-(6-alkyl-bicyclo-(3.3.0)-octan-3-yliden) -essigsaeure-derivaten mit ueberwiegendem anteil des e-isomeren
EP0867185B1 (en) * 1996-09-17 2002-06-12 Toray Industries, Inc. Platelet function potentiator and method of curing platelet dysfunction
KR20070054644A (ko) * 2004-07-26 2007-05-29 액테리온 파마슈티칼 리미티드 미립자 제형으로 흡입된 일로프로스트에 의한 폐고혈압의치료
JP5271272B2 (ja) 2006-11-16 2013-08-21 ジェンムス ファーマ インコーポレイティド Ａ型インフルエンザウィルス感染の治療のための薬剤としてのｅｐ２およびｅｐ４作動薬
WO2011047048A1 (en) 2009-10-14 2011-04-21 Gemmus Pharma, Inc. Combination therapy treatment for viral infections
TWI513462B (zh) 2009-11-13 2015-12-21 Toray Industries 糖尿病之治療或預防藥
JP6694385B2 (ja) 2013-08-09 2020-05-13 アーデリクス，インコーポレーテッド リン酸塩輸送阻害のための化合物及び方法
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3048906A1 (de) * 1980-12-19 1982-07-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3121155A1 (de) * 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
IE56703B1 (en) 1991-11-06
AU2401584A (en) 1984-08-23
ATE38831T1 (de) 1988-12-15
IL70905A (en) 1987-02-27
DE3306123A1 (de) 1984-09-06
GR81961B (es) 1984-12-12
IE840236L (en) 1984-08-18
YU45173B (en) 1992-05-28
EP0119949B1 (de) 1988-11-23
DK55584D0 (da) 1984-02-08
NO840595L (no) 1984-08-20
FI840635A0 (fi) 1984-02-16
FI78065B (fi) 1989-02-28
JPS59157050A (ja) 1984-09-06
IL70905A0 (en) 1984-05-31
FI840635A (fi) 1984-08-19
FI78065C (fi) 1989-06-12
NO157060B (no) 1987-10-05
CS270552B2 (en) 1990-07-12
PH21468A (en) 1987-10-28
DK55584A (da) 1984-08-19
DD216448A5 (de) 1984-12-12
AU580728B2 (en) 1989-02-02
DK155828B (da) 1989-05-22
DE3475302D1 (en) 1988-12-29
US5013758A (en) 1991-05-07
ZA841198B (en) 1984-09-26
SU1384196A3 (ru) 1988-03-23
EP0119949A1 (de) 1984-09-26
JPH0611726B2 (ja) 1994-02-16
NZ207061A (en) 1987-06-30
DK155828C (da) 1989-10-09
YU24484A (en) 1986-06-30
ES8500209A1 (es) 1984-11-01
HU191994B (en) 1987-04-28
CA1251200A (en) 1989-03-14
CS103684A2 (en) 1989-11-14
NO157060C (no) 1988-01-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040601