ES510751A0 - Procedimiento para la produccion de un polipeptido. - Google Patents

Procedimiento para la produccion de un polipeptido.

Info

Publication number
ES510751A0
ES510751A0 ES510751A ES510751A ES510751A0 ES 510751 A0 ES510751 A0 ES 510751A0 ES 510751 A ES510751 A ES 510751A ES 510751 A ES510751 A ES 510751A ES 510751 A0 ES510751 A0 ES 510751A0
Authority
ES
Spain
Prior art keywords
polypeptide
procedure
production
monocyclic
pancreatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES510751A
Other languages
English (en)
Other versions
ES8305701A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES8305701A1 publication Critical patent/ES8305701A1/es
Publication of ES510751A0 publication Critical patent/ES510751A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ES510751A 1979-11-27 1982-03-24 Procedimiento para la produccion de un polipeptido. Granted ES510751A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1052479 1979-11-27
CH457480 1980-06-13

Publications (2)

Publication Number Publication Date
ES8305701A1 ES8305701A1 (es) 1983-04-16
ES510751A0 true ES510751A0 (es) 1983-04-16

Family

ID=25695798

Family Applications (2)

Application Number Title Priority Date Filing Date
ES497113A Expired ES8301463A1 (es) 1979-11-27 1980-11-25 Procedimiento para la produccion de un polipeptido
ES510751A Granted ES510751A0 (es) 1979-11-27 1982-03-24 Procedimiento para la produccion de un polipeptido.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES497113A Expired ES8301463A1 (es) 1979-11-27 1980-11-25 Procedimiento para la produccion de un polipeptido

Country Status (25)

Country Link
US (1) US4395403A (es)
EP (1) EP0029579B1 (es)
JP (1) JPS5690048A (es)
AT (1) ATE2512T1 (es)
AU (1) AU543198B2 (es)
CA (1) CA1182109A (es)
CS (1) CS228140B2 (es)
CY (1) CY1327A (es)
DE (2) DE3062075D1 (es)
DK (1) DK150146C (es)
ES (2) ES8301463A1 (es)
FI (1) FI72981C (es)
GR (1) GR71636B (es)
HK (1) HK30686A (es)
HU (1) HU185920B (es)
IE (1) IE50571B1 (es)
IL (1) IL61561A (es)
KE (1) KE3606A (es)
LU (1) LU88344I2 (es)
MY (1) MY8500072A (es)
NL (1) NL930137I2 (es)
NZ (1) NZ195640A (es)
PH (1) PH22841A (es)
PT (1) PT72103B (es)
SG (1) SG8786G (es)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK81082A (da) * 1981-03-06 1982-09-07 Sandoz Ag Fremgangsmaade til fremstilling af polypeptider
CH655505B (es) * 1982-08-24 1986-04-30
US4663435A (en) * 1982-12-06 1987-05-05 Merck & Co., Inc. Bridged cyclic hexapeptide somatostatin analogs
FR2554347B1 (fr) * 1983-11-07 1986-10-03 Immunotech Sa Acide pressinique, ses derives aminoacides substitues et homologues de configuration d ainsi que les derives n- et c- terminal-substitues et leurs applications dans les domaines therapeutique, biologique ou immunologique
US4684620A (en) * 1984-09-04 1987-08-04 Gibson-Stephens Neuropharmaceuticals, Inc. Cyclic polypeptides having mu-receptor specificity
GB8423431D0 (en) * 1984-09-17 1984-10-24 Sandoz Ltd Organic compounds
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
US4904642A (en) * 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
JPH085913B2 (ja) * 1985-09-12 1996-01-24 ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド 治療用ソマトスタチン同族体
HU198626B (en) * 1986-05-27 1989-11-28 Sandoz Ag Process for producing pharmaceutical compositions comprising somatostatin analogues as active ingredient
US4853371A (en) * 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
GB8620035D0 (en) * 1986-08-18 1986-10-01 Sandoz Ltd Organic compounds
DE3726517A1 (de) * 1986-08-18 1988-03-03 Sandoz Ag Nasale zusammensetzungen, welche octreotid enthalten
GB2193891B (en) * 1986-08-18 1990-07-25 Sandoz Ltd Nasal pharmaceutical composition containing a somatostatin anologue.
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
DE3790635B4 (de) * 1986-10-13 2007-11-22 Novartis Ag Verfahren zur Herstellung eines Peptidalkohols und Ausgangsverbindungen dafür
US4871717A (en) * 1987-01-07 1989-10-03 Administrators Of The Tulane Educational Fund Peptides
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
DK375789A (da) * 1988-08-18 1990-02-19 Syntex Inc Peptidderivater
US5006510A (en) * 1989-06-20 1991-04-09 Ellis Wladislaw V Method for relieving chronic pain with a somatostatin analog composition
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
US5084443A (en) * 1989-12-04 1992-01-28 Biomeasure, Inc. Promoting expression of acetylcholine receptors with lhrh antagonist
DE69027767T2 (de) * 1989-12-08 1997-01-02 Univ Tulane Oktapeptidanaloge von somatostatin mit threonin in position 6
IE920416A1 (en) * 1991-02-08 1992-08-12 Biomeasure Method of treating benign and malignant proliferative skin¹disease
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
GB9402767D0 (en) * 1994-02-14 1994-04-06 Sandoz Ltd Improvements in or relating to organic compounds
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
EP0824103A1 (en) * 1996-08-13 1998-02-18 Chang-Shinn Su Method for synthesis of Tyr-3-octreotide
US6262229B1 (en) 1996-12-04 2001-07-17 Biomeasure Incorporated Somatostatin antagonists
PT980253E (pt) * 1997-05-13 2004-08-31 Conseils De Rec Appl Scient S Somatostatina e agonistas de somatostatina para tratar a insensibilidade a insulina e a sindrome x
DE69816808T2 (de) * 1997-05-13 2004-04-15 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin agoniste zur reduzierung von körpergewicht
AU8019798A (en) * 1997-05-13 1998-12-08 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Method and compositions for treating hyperlipidemia and other conditions
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
ES2144357B1 (es) 1998-01-29 2000-12-16 Lipotec Sa Procedimiento para la obtencion del analogo de somatostatina octreotide.
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
US6159935A (en) 1999-11-29 2000-12-12 Pharmacia & Upjohn Co. Method for preventing diarrhea
RU2196144C1 (ru) * 2001-05-14 2003-01-10 Самуков Владимир Васильевич Защищенные производные октреотида
CN101481405A (zh) 2001-06-08 2009-07-15 研究及应用科学协会股份有限公司 生长激素释放抑制因子-多巴胺嵌合类似物
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
US6987167B2 (en) 2002-05-22 2006-01-17 Wockhardt Limited Process for production of the somatostatin analog, octreotide
US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
ES2237356T3 (es) * 2003-04-07 2007-04-01 Novetide Ltd. Procedimiento para la produccion de peptidos ciclicos.
EP1624884A4 (en) 2003-04-22 2009-08-05 Ipsen Pharma SOMATOSTATIN VECTORS
WO2006041945A2 (en) * 2004-10-04 2006-04-20 Novetide, Ltd. A counterion exchange process for peptides
KR20130024987A (ko) * 2005-12-22 2013-03-08 노파르티스 아게 옥트레오티드 및 ２종 이상의 폴리락티드-코-글리콜리드 중합체를 포함하는 서방형 제제
EP2013226A2 (en) * 2006-03-28 2009-01-14 Wockhardt Limited Processes for the preparation of octreotide
TW200819137A (en) * 2006-10-31 2008-05-01 Iner Aec Executive Yuan Method for preparation of lipid-spacer radical- reactions of functional group-peptide
US20090082259A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched octreotide
EP2172189A1 (en) 2008-10-01 2010-04-07 Novartis AG Pharmaceutical Compositions
EP2213307A1 (en) 2009-02-03 2010-08-04 Novartis AG Injectable depot formulations
US8377891B2 (en) 2008-11-07 2013-02-19 Usv, Ltd. Process for synthesis of cyclic octapeptide
US20120053172A1 (en) 2009-02-12 2012-03-01 Cooperatieve Mirzorg U.A. Use of a combination of diazoxide and metformin for treating obesity or obesity related disorders
WO2013046233A2 (en) 2011-09-30 2013-04-04 Mylan Laboratories Ltd Process for the preparation of octreotide acetate
CN103102390B (zh) * 2011-11-09 2015-01-28 杭州华津允上医药有限公司 一种奥曲肽的制备方法
WO2013132505A1 (en) 2012-03-09 2013-09-12 Natco Pharma Limited Improved process for preparation of octreotide by solution phase peptide synthesis
DK3007704T3 (da) 2013-06-13 2021-03-29 Antisense Therapeutics Ltd Kombinationsterapi til akromegali
CN108395469A (zh) * 2018-02-01 2018-08-14 滨海吉尔多肽有限公司 一种假脯氨酸二肽的合成方法
GB202012334D0 (en) 2020-08-07 2020-09-23 Avon Polymer Prod Ltd Monitoring system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105603A (en) * 1977-03-28 1978-08-08 The Salk Institute For Biological Studies Peptides which effect release of hormones
US4139526A (en) * 1977-12-01 1979-02-13 Merck & Co., Inc. Somatostatin analogs
US4140767A (en) * 1977-12-01 1979-02-20 Merck & Co., Inc. Somatostatin analogs
US4190648A (en) * 1979-03-13 1980-02-26 Merck & Co., Inc. Peptides having somatostatin activity
US4225472A (en) * 1979-05-29 1980-09-30 American Home Products Corporation Truncated somatostatin analogs
US4310518A (en) * 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4282143A (en) * 1980-06-13 1981-08-04 American Home Products Corporation Octapeptides lowering growth hormone

Also Published As

Publication number Publication date
IL61561A (en) 1985-02-28
CY1327A (en) 1986-06-27
NL930137I2 (nl) 1997-02-03
ES8305701A1 (es) 1983-04-16
PH22841A (en) 1989-01-19
DK150146B (da) 1986-12-15
KE3606A (en) 1986-03-17
IE50571B1 (en) 1986-05-14
AU543198B2 (en) 1985-04-04
JPS6351159B2 (es) 1988-10-13
PT72103A (fr) 1980-12-01
DK501980A (da) 1981-05-28
NL930137I1 (nl) 1993-11-01
ES497113A0 (es) 1982-12-01
DE3062075D1 (en) 1983-03-24
HU185920B (en) 1985-04-28
DK150146C (da) 1987-06-01
HK30686A (en) 1986-05-09
JPS5690048A (en) 1981-07-21
CS228140B2 (en) 1984-05-14
NZ195640A (en) 1984-07-06
ATE2512T1 (de) 1983-03-15
SG8786G (en) 1987-03-27
IE802452L (en) 1981-05-27
PT72103B (fr) 1982-01-28
DE19375086I2 (de) 2003-01-09
IL61561A0 (en) 1980-12-31
MY8500072A (en) 1985-12-31
ES8301463A1 (es) 1982-12-01
LU88344I2 (fr) 1994-05-04
FI803634L (fi) 1981-05-28
AU6468880A (en) 1981-06-04
CA1182109A (en) 1985-02-05
EP0029579B1 (en) 1983-02-16
FI72981B (fi) 1987-04-30
US4395403A (en) 1983-07-26
EP0029579A1 (en) 1981-06-03
FI72981C (fi) 1987-08-10
GR71636B (es) 1983-06-20

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20030211