ES483053A1 - Un procedimiento para preparar octahidro y hexahidro (b) ci-clohepta (d) piranos - Google Patents

Un procedimiento para preparar octahidro y hexahidro (b) ci-clohepta (d) piranos

Info

Publication number
ES483053A1
ES483053A1 ES483053A ES483053A ES483053A1 ES 483053 A1 ES483053 A1 ES 483053A1 ES 483053 A ES483053 A ES 483053A ES 483053 A ES483053 A ES 483053A ES 483053 A1 ES483053 A1 ES 483053A1
Authority
ES
Spain
Prior art keywords
benzocycloheptapyrans
preparation
pharmaceutical formulations
formulations containing
hexahydrobenzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES483053A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES483053A1 publication Critical patent/ES483053A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Un procedimiento para preparar octahidro y hexahidro [b] ciclohepta [d] piranos de la fórmula **(Fórmula-01)** en donde R1 es hidrógeno o alcanoílo de 1 a 4 átomos de carbono; R2 es alquilo de 5 a 10 átomos de carbono o alquenilo de 5 a 10 átomos de carbono; R3 es hidrógeno o metilo; y Z es **(Fórmula-02)** cuyo procedimiento consiste en hacer reaccionar el compuesto de fórmula **(Fórmula-03)** donde Z'' es **(Fórmula-04)** con p-toluensulfonilhidrazina y una base fuerte.
ES483053A 1978-03-09 1979-08-01 Un procedimiento para preparar octahidro y hexahidro (b) ci-clohepta (d) piranos Expired ES483053A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/884,883 US4152451A (en) 1978-03-09 1978-03-09 Benzocycloheptapyrans, compositions, and method of treatment

Publications (1)

Publication Number Publication Date
ES483053A1 true ES483053A1 (es) 1980-10-01

Family

ID=25385629

Family Applications (3)

Application Number Title Priority Date Filing Date
ES478415A Expired ES478415A1 (es) 1978-03-09 1979-03-08 Un procedimiento para preparar octahidro y hexahidro -b-ci- clohepta-d-piranos.
ES483053A Expired ES483053A1 (es) 1978-03-09 1979-08-01 Un procedimiento para preparar octahidro y hexahidro (b) ci-clohepta (d) piranos
ES483052A Expired ES8100288A1 (es) 1978-03-09 1979-08-01 Un procedimiento para preparar octahidro y hexahidro(b)ciclohepta(d)piranos.(como divisional de la patente numero 478.415)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES478415A Expired ES478415A1 (es) 1978-03-09 1979-03-08 Un procedimiento para preparar octahidro y hexahidro -b-ci- clohepta-d-piranos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES483052A Expired ES8100288A1 (es) 1978-03-09 1979-08-01 Un procedimiento para preparar octahidro y hexahidro(b)ciclohepta(d)piranos.(como divisional de la patente numero 478.415)

Country Status (29)

Country Link
US (1) US4152451A (es)
EP (1) EP0004172B1 (es)
JP (1) JPS54125675A (es)
AR (1) AR223666A1 (es)
AT (1) AT362791B (es)
AU (1) AU522313B2 (es)
BG (1) BG33285A3 (es)
CA (1) CA1122992A (es)
CH (1) CH638801A5 (es)
CS (1) CS204049B2 (es)
DD (1) DD142339A5 (es)
DE (1) DE2962416D1 (es)
DK (1) DK96479A (es)
EG (1) EG13883A (es)
ES (3) ES478415A1 (es)
FI (1) FI790711A (es)
FR (1) FR2419290A1 (es)
GB (1) GB2017089B (es)
GR (1) GR72750B (es)
HU (1) HU179971B (es)
IE (1) IE47870B1 (es)
IL (1) IL56736A (es)
NZ (1) NZ189781A (es)
PH (2) PH14643A (es)
PL (5) PL117710B1 (es)
PT (1) PT69287A (es)
RO (5) RO82380A (es)
SU (1) SU824894A3 (es)
ZA (1) ZA791108B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4442089A (en) * 1982-07-06 1984-04-10 E. R. Squibb & Sons, Inc. Method for treating glaucoma with topical or systemic ACE inhibitor compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA994791A (en) * 1971-05-12 1976-08-10 Louis S. Harris Esters of benzopyrans
US3941782A (en) * 1972-04-27 1976-03-02 Sharps Associates Heterocyclic esters of benzopyrans
US4025630A (en) * 1973-09-19 1977-05-24 Abbott Laboratories Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication
US4051152A (en) * 1976-01-07 1977-09-27 Sharps Associates Oxo C-ring benzopyrans

Also Published As

Publication number Publication date
PL120418B1 (en) 1982-02-27
FR2419290A1 (fr) 1979-10-05
PT69287A (en) 1979-03-01
AT362791B (de) 1981-06-10
HU179971B (en) 1983-01-28
ZA791108B (en) 1980-10-29
ES483052A0 (es) 1980-11-01
ATA175279A (de) 1980-11-15
DE2962416D1 (en) 1982-05-19
GB2017089B (en) 1982-09-22
FR2419290B1 (es) 1981-05-29
DK96479A (da) 1979-09-10
RO82377A (ro) 1983-08-03
PL214011A1 (es) 1980-02-25
EP0004172B1 (en) 1982-04-07
FI790711A (fi) 1979-09-10
GB2017089A (en) 1979-10-03
EP0004172A1 (en) 1979-09-19
RO76885A (ro) 1982-02-26
PH14643A (en) 1981-10-12
NZ189781A (en) 1980-10-24
RO82379A (ro) 1983-08-03
RO82378B (ro) 1983-07-30
CA1122992A (en) 1982-05-04
BG33285A3 (en) 1983-01-14
PL120416B1 (en) 1982-02-27
PL120366B1 (en) 1982-02-27
DD142339A5 (de) 1980-06-18
SU824894A3 (ru) 1981-04-23
CS204049B2 (en) 1981-03-31
ES8100288A1 (es) 1980-11-01
RO82377B (ro) 1983-07-30
GR72750B (es) 1983-12-02
IE790712L (en) 1979-09-09
PL120365B1 (en) 1982-02-27
RO82380A (ro) 1983-08-03
AR223666A1 (es) 1981-09-15
CH638801A5 (fr) 1983-10-14
AU522313B2 (en) 1982-05-27
AU4493579A (en) 1979-09-13
IE47870B1 (en) 1984-07-11
IL56736A (en) 1982-08-31
RO82380B (ro) 1983-07-30
US4152451A (en) 1979-05-01
RO82378A (ro) 1983-08-03
JPS54125675A (en) 1979-09-29
PH16051A (en) 1983-06-02
PL117710B1 (en) 1981-08-31
RO82379B (ro) 1983-07-30
EG13883A (en) 1982-12-31
ES478415A1 (es) 1980-01-16
IL56736A0 (en) 1979-05-31

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