ES463737A1 - Metodo para producir cefalosporinas y similares - Google Patents

Metodo para producir cefalosporinas y similares

Info

Publication number
ES463737A1
ES463737A1 ES463737A ES463737A ES463737A1 ES 463737 A1 ES463737 A1 ES 463737A1 ES 463737 A ES463737 A ES 463737A ES 463737 A ES463737 A ES 463737A ES 463737 A1 ES463737 A1 ES 463737A1
Authority
ES
Spain
Prior art keywords
group
substituted
methoxy
unsubstituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463737A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOUMITOMO CHEMICAL Co LIM
Original Assignee
SOUMITOMO CHEMICAL Co LIM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOUMITOMO CHEMICAL Co LIM filed Critical SOUMITOMO CHEMICAL Co LIM
Publication of ES463737A1 publication Critical patent/ES463737A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Método para producir cefalosporinas y similares, de la fórmula (Ia): **(Fórmula)** en que A es un anillo heteroaromático mono o policíclico que contiene por lo menos un átomo de nitrógeno como heteroátomo que puede ser insubstituido o estar substituido con uno o más substituyentes; R es un grupo fenilo que puede ser insubstituido o estar substituido, un grupo tienilo, un grupo furilo, un grupo ciclohexadienilo o un grupo ciclohexenilo;: Het es un anillo heterocíclico que contiene de 1 a 5 átomos de oxígeno, nitrógeno y azufre, en que el sistema del anillo puede ser policíclico o monocíclico de 5 ó 6 miembros y que puede ser insubstituido o estar substituido y M es un átomo de hidrógeno o un grupo protector de carboxilo biológicamente activo, y sus sales farmacéuticamente aceptables, caracterizado porque comprende hacer reaccionar un compuesto en que A, R y M son como se ha definido anteriormente, con un compuesto de la fórmula(V): HS-Het (V) en que Het es como se ha definido anteriormente.
ES463737A 1975-11-28 1977-10-31 Metodo para producir cefalosporinas y similares Expired ES463737A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50142647A JPS5268193A (en) 1975-11-28 1975-11-28 Synthesis of novel cephalosporin derivatives

Publications (1)

Publication Number Publication Date
ES463737A1 true ES463737A1 (es) 1979-01-01

Family

ID=15320206

Family Applications (4)

Application Number Title Priority Date Filing Date
ES453726A Expired ES453726A1 (es) 1975-11-28 1976-11-27 Procedimiento para producir cefalosporinas y similares.
ES463736A Expired ES463736A1 (es) 1975-11-28 1977-10-31 Procedimiento de obtencion de cefalosporinas y analogos.
ES463737A Expired ES463737A1 (es) 1975-11-28 1977-10-31 Metodo para producir cefalosporinas y similares
ES463735A Expired ES463735A1 (es) 1975-11-28 1977-10-31 Metodo de obtencion de cefalosporinas y similares.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES453726A Expired ES453726A1 (es) 1975-11-28 1976-11-27 Procedimiento para producir cefalosporinas y similares.
ES463736A Expired ES463736A1 (es) 1975-11-28 1977-10-31 Procedimiento de obtencion de cefalosporinas y analogos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES463735A Expired ES463735A1 (es) 1975-11-28 1977-10-31 Metodo de obtencion de cefalosporinas y similares.

Country Status (19)

Country Link
US (2) US4125611A (es)
JP (1) JPS5268193A (es)
AT (4) AT352273B (es)
BE (1) BE848887A (es)
CA (1) CA1086716A (es)
CH (1) CH625527A5 (es)
CS (4) CS212257B2 (es)
DD (1) DD128562A5 (es)
DE (1) DE2653820A1 (es)
DK (1) DK535476A (es)
ES (4) ES453726A1 (es)
FR (1) FR2332758A1 (es)
GB (1) GB1532866A (es)
HU (1) HU173394B (es)
NL (1) NL7613206A (es)
NO (1) NO764054L (es)
NZ (1) NZ182740A (es)
SE (1) SE7613304L (es)
ZA (1) ZA767088B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5268193A (en) * 1975-11-28 1977-06-06 Sumitomo Chem Co Ltd Synthesis of novel cephalosporin derivatives
AT375376B (de) * 1980-03-04 1984-07-25 Eisai Co Ltd Verfahren zur herstellung von neuen 7alphamethoxycephalosporinderivaten
US4503052A (en) * 1983-05-16 1985-03-05 Eli Lilly And Company 7-(2-(Substituted cinnolinoyl)amino)acetamido)-1-oxa-beta-lactams
EP1134214A4 (en) * 1998-11-04 2004-12-15 Meiji Seika Kaisha PICOLINAMIDE DERIVATIVES AND PESTICIDES CONTAINING THESE DERIVATIVES AS ACTIVE INGREDIENT
ES2184705T3 (es) 1999-03-09 2003-04-16 Upjohn Co 4-oxo-4,7-dihidro-tieno(2,3-b)piridina-5-carboxamidas como agentes antivirales.
US7148237B2 (en) * 2001-03-01 2006-12-12 Shionogi & Co., Ltd. Nitrogen-containing heteroaryl compounds having HIV integrase inhibitory activity
WO2003020729A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANT IVIRAL AGENTS
WO2003020728A1 (en) * 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
AR038117A1 (es) * 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038118A1 (es) * 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
AR038294A1 (es) * 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
CA2472372C (en) * 2002-01-17 2010-08-17 Melissa Egbertson Hydroxynaphthyridinone carboxamides useful as hiv integrase inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1109860A (en) * 1972-12-08 1981-09-29 Shinji Terao Process for producing lactol-type cephalosporins
US4068074A (en) * 1974-04-05 1978-01-10 Yamanouchi Pharmaceutical Co., Ltd. Cephalosporin derivatives having at the 3-position of the cephem ring a heterocyclic thiomethyl group with a carboxy or sulfo group and at the 7-position of the cephem ring an α-heterocylic acylaminophenyl-acetamide group
CH606001A5 (es) * 1974-05-13 1978-10-13 Ciba Geigy Ag
US3989687A (en) * 1974-09-27 1976-11-02 Richardson-Merrell Inc. 4-Oxo-1-pyridinyl penicillin derivatives
JPS5268193A (en) * 1975-11-28 1977-06-06 Sumitomo Chem Co Ltd Synthesis of novel cephalosporin derivatives

Also Published As

Publication number Publication date
NO764054L (es) 1977-06-01
HU173394B (hu) 1979-04-28
SE7613304L (sv) 1977-05-29
ATA679A (de) 1979-10-15
NL7613206A (nl) 1977-06-01
US4125611A (en) 1978-11-14
BE848887A (fr) 1977-03-16
ES463735A1 (es) 1978-12-16
CS212259B2 (cs) 1982-03-26
ES463736A1 (es) 1978-12-16
FR2332758B1 (es) 1981-11-27
ZA767088B (en) 1977-10-26
CS212260B2 (cs) 1982-03-26
CS212258B2 (cs) 1982-03-26
JPS5268193A (en) 1977-06-06
CH625527A5 (es) 1981-09-30
AT356817B (de) 1980-05-27
DD128562A5 (de) 1977-11-23
AT352273B (de) 1979-09-10
NZ182740A (en) 1979-01-11
DK535476A (da) 1977-05-29
ES453726A1 (es) 1978-01-16
GB1532866A (en) 1978-11-22
AU2001876A (en) 1978-06-01
ATA581778A (de) 1979-02-15
DE2653820A1 (de) 1977-06-02
CA1086716A (en) 1980-09-30
US4226863A (en) 1980-10-07
ATA581678A (de) 1979-05-15
AT353970B (de) 1979-12-10
CS212257B2 (en) 1982-03-26
AT352282B (de) 1979-09-10
ATA879876A (de) 1979-02-15
FR2332758A1 (fr) 1977-06-24

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