ES462784A1 - Procedimiento para la produccion de cromanonas. - Google Patents

Procedimiento para la produccion de cromanonas.

Info

Publication number
ES462784A1
ES462784A1 ES462784A ES462784A ES462784A1 ES 462784 A1 ES462784 A1 ES 462784A1 ES 462784 A ES462784 A ES 462784A ES 462784 A ES462784 A ES 462784A ES 462784 A1 ES462784 A1 ES 462784A1
Authority
ES
Spain
Prior art keywords
formula
dibenzopyran
novel
preparation
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462784A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES462784A1 publication Critical patent/ES462784A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Abstract

Procedimiento para la producción de cromanonas de la fórmula: ***(Ver fórmula) útiles como intermedios en la producción de dibenzo[b,d]piranos, caracterizados porque se hace reaccionar un compuesto de la fórmula: ***(Ver fórmula) con formiato de etilo en presencia de hidróxido de sodio, en donde R4, R5, Z y W son como sigue: cada uno de R4 y R5 se selecciona del grupo que consta de hidrógeno, metilo y etilo.
ES462784A 1975-11-03 1977-09-29 Procedimiento para la produccion de cromanonas. Expired ES462784A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62821075A 1975-11-03 1975-11-03

Publications (1)

Publication Number Publication Date
ES462784A1 true ES462784A1 (es) 1978-06-01

Family

ID=24517939

Family Applications (3)

Application Number Title Priority Date Filing Date
ES452772A Expired ES452772A1 (es) 1975-11-03 1976-10-27 Un procedimiento para la produccion de un dibenzo (b-d)-pi- rano.
ES462784A Expired ES462784A1 (es) 1975-11-03 1977-09-29 Procedimiento para la produccion de cromanonas.
ES462783A Expired ES462783A1 (es) 1975-11-03 1977-09-29 Procedimiento para la produccion de dibenzo(d,b)piranos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES452772A Expired ES452772A1 (es) 1975-11-03 1976-10-27 Un procedimiento para la produccion de un dibenzo (b-d)-pi- rano.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES462783A Expired ES462783A1 (es) 1975-11-03 1977-09-29 Procedimiento para la produccion de dibenzo(d,b)piranos.

Country Status (25)

Country Link
JP (3) JPS5277065A (es)
AR (1) AR220521A1 (es)
BG (3) BG27552A3 (es)
CA (1) CA1099269A (es)
CH (1) CH622790A5 (es)
CS (1) CS207571B2 (es)
DD (3) DD129214A5 (es)
DK (1) DK495876A (es)
EG (1) EG12648A (es)
ES (3) ES452772A1 (es)
FI (1) FI763131A (es)
GR (1) GR65202B (es)
HU (1) HU178321B (es)
IE (1) IE43700B1 (es)
IL (1) IL50717A (es)
NO (1) NO148745C (es)
NZ (1) NZ182368A (es)
PH (3) PH14811A (es)
PL (1) PL125297B1 (es)
PT (1) PT65781B (es)
RO (4) RO71411A (es)
SE (1) SE432251B (es)
SU (4) SU843748A3 (es)
YU (1) YU268176A (es)
ZA (1) ZA766281B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0765890A (ja) * 1993-08-26 1995-03-10 Sumitomo Wiring Syst Ltd コネクタ
JP2988237B2 (ja) * 1994-01-31 1999-12-13 住友電装株式会社 簡易防水コネクタ
JP5037799B2 (ja) * 2005-06-30 2012-10-03 パナソニック株式会社 テレビコンセント
JP2021196016A (ja) 2020-06-16 2021-12-27 株式会社アイシン シフト装置

Also Published As

Publication number Publication date
SU677660A3 (ru) 1979-07-30
PT65781B (en) 1978-05-10
BG28058A4 (en) 1980-02-25
IL50717A0 (en) 1976-12-31
HU178321B (en) 1982-04-28
DD137837A5 (de) 1979-09-26
RO71411A (ro) 1982-12-06
FI763131A (es) 1977-05-04
GR65202B (en) 1980-07-29
DD143774A5 (de) 1980-09-10
IE43700L (en) 1977-05-03
CS207571B2 (en) 1981-08-31
PL125297B1 (en) 1983-04-30
IE43700B1 (en) 1981-05-06
PH14811A (en) 1981-12-14
PH14383A (en) 1981-06-24
CA1099269A (en) 1981-04-14
NZ182368A (en) 1978-04-03
RO75876A (ro) 1981-05-30
JPS5277065A (en) 1977-06-29
SE7611275L (sv) 1977-06-27
SU677661A3 (ru) 1979-07-30
DK495876A (da) 1977-05-04
ES462783A1 (es) 1978-06-01
JPS564555B2 (es) 1981-01-30
SU843748A3 (ru) 1981-06-30
BG28057A4 (en) 1980-02-25
DD129214A5 (de) 1978-01-04
ZA766281B (en) 1977-09-28
SU784772A4 (ru) 1980-11-30
PT65781A (en) 1976-12-01
JPS5589280A (en) 1980-07-05
NO148745C (no) 1983-12-07
IL50717A (en) 1981-09-13
EG12648A (en) 1979-06-30
ES452772A1 (es) 1978-02-16
YU268176A (en) 1983-10-31
JPS5943958B2 (ja) 1984-10-25
CH622790A5 (en) 1981-04-30
RO76006A (ro) 1981-03-30
SE432251B (sv) 1984-03-26
JPS56103173A (en) 1981-08-18
BG27552A3 (en) 1979-11-12
PH16788A (en) 1984-02-28
RO76124A (ro) 1981-04-30
JPS5943955B2 (ja) 1984-10-25
AR220521A1 (es) 1980-11-14
NO763725L (es) 1977-05-04
PL193435A1 (es) 1980-01-28
NO148745B (no) 1983-08-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103