ES462071A1 - Procedimiento de preparacion de n-2,6-diclorofenil-2-amino- pirimidina. - Google Patents

Procedimiento de preparacion de n-2,6-diclorofenil-2-amino- pirimidina.

Info

Publication number
ES462071A1
ES462071A1 ES462071A ES462071A ES462071A1 ES 462071 A1 ES462071 A1 ES 462071A1 ES 462071 A ES462071 A ES 462071A ES 462071 A ES462071 A ES 462071A ES 462071 A1 ES462071 A1 ES 462071A1
Authority
ES
Spain
Prior art keywords
compound
pyrimidine derivative
disclosed
aminopyrimidine
dichloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES462071A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Publication of ES462071A1 publication Critical patent/ES462071A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento de preparación de N-2,6-diclorofenil-2-aminopirimida de fórmula: ***(Ver fórmula I) consistente en hacer reaccionar 2,6-dicloroanilina y 2-cloropirimidina, en solución en dimetilformamida y en presencia de hidruro sódico, preferiblemente a una temperatura que no exceda de 40º.
ES462071A 1976-09-03 1977-09-02 Procedimiento de preparacion de n-2,6-diclorofenil-2-amino- pirimidina. Expired ES462071A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB36523/76A GB1534593A (en) 1976-09-03 1976-09-03 N-2,6-dichlorophenyl-2-aminopyrimidine and therapeutic compositions containing it

Publications (1)

Publication Number Publication Date
ES462071A1 true ES462071A1 (es) 1978-06-01

Family

ID=10388933

Family Applications (1)

Application Number Title Priority Date Filing Date
ES462071A Expired ES462071A1 (es) 1976-09-03 1977-09-02 Procedimiento de preparacion de n-2,6-diclorofenil-2-amino- pirimidina.

Country Status (28)

Country Link
US (1) US4100287A (es)
JP (1) JPS5331681A (es)
AR (1) AR212375A1 (es)
AT (1) AT353797B (es)
AU (1) AU509295B2 (es)
BE (1) BE857992A (es)
CA (1) CA1079732A (es)
CH (1) CH622251A5 (es)
DE (1) DE2739659C3 (es)
DK (1) DK142847B (es)
EG (1) EG12895A (es)
ES (1) ES462071A1 (es)
FI (1) FI63564C (es)
FR (2) FR2363560A1 (es)
GB (1) GB1534593A (es)
HK (1) HK59179A (es)
IE (1) IE45480B1 (es)
LU (1) LU77999A1 (es)
MX (1) MX4997E (es)
MY (1) MY8000098A (es)
NL (1) NL163782C (es)
NO (1) NO145790C (es)
NZ (1) NZ184908A (es)
OA (1) OA05751A (es)
PH (1) PH15051A (es)
PT (1) PT66991B (es)
SE (1) SE442635B (es)
ZA (1) ZA774842B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US7514447B2 (en) * 2005-09-27 2009-04-07 Irm Llc Diarylamine-containing compounds and compositions, and their use as modulators of c-kit receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1670537A1 (de) * 1966-11-09 1970-10-29 Degussa Verfahren zur Herstellung neuer substituierter Aminopyrimidine
US3481932A (en) * 1967-09-01 1969-12-02 Searle & Co 2-anilino-5-methyl-6-phenylpyrimidines and congeners
DE1958212C3 (de) * 1969-11-19 1978-12-07 C.H. Boehringer Sohn, 6507 Ingelheim Substituierte 2- [N-(2-Chlorphenyl)-N-(cycloalkyl)amino] -imidazoline- (2), deren Säureadditionssalze, Verfahren zu ihrer Herstellung und deren Verwendung
CH593266A5 (es) * 1973-09-20 1977-11-30 Delalande Sa

Also Published As

Publication number Publication date
NZ184908A (en) 1978-11-13
US4100287A (en) 1978-07-11
AT353797B (de) 1979-12-10
PT66991A (en) 1977-10-01
FR2363560B1 (es) 1980-05-16
FI63564C (fi) 1983-07-11
PT66991B (en) 1979-02-13
FR2363561B1 (es) 1980-05-16
ZA774842B (en) 1978-06-28
DE2739659C3 (de) 1987-09-10
NO145790B (no) 1982-02-22
DK391377A (es) 1978-03-04
AR212375A1 (es) 1978-06-30
NO773039L (no) 1978-03-06
MY8000098A (en) 1980-12-31
SE7709852L (sv) 1978-03-04
JPS5422993B2 (es) 1979-08-10
NO145790C (no) 1982-06-02
AU2852377A (en) 1979-03-08
FI772503A (fi) 1978-03-04
AU509295B2 (en) 1980-05-01
DE2739659B2 (de) 1979-10-04
EG12895A (en) 1980-03-31
ATA585477A (de) 1979-05-15
JPS5331681A (en) 1978-03-25
MX4997E (es) 1983-02-02
NL7709272A (nl) 1978-03-07
FR2363561A1 (fr) 1978-03-31
DK142847C (es) 1981-09-21
SE442635B (sv) 1986-01-20
IE45480B1 (en) 1982-09-08
BE857992A (fr) 1977-12-16
PH15051A (en) 1982-05-20
HK59179A (en) 1979-08-31
FR2363560A1 (fr) 1978-03-31
CH622251A5 (es) 1981-03-31
DE2739659A1 (de) 1978-03-09
FI63564B (fi) 1983-03-31
CA1079732A (en) 1980-06-17
OA05751A (fr) 1981-05-31
NL163782C (nl) 1980-10-15
NL163782B (nl) 1980-05-16
LU77999A1 (es) 1978-01-11
IE45480L (en) 1978-03-03
GB1534593A (en) 1978-12-06
DK142847B (da) 1981-02-09

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