ES424432A1 - Procedimiento para la preparacion de nuevas bencilaminas. - Google Patents

Procedimiento para la preparacion de nuevas bencilaminas.

Info

Publication number
ES424432A1
ES424432A1 ES424432A ES424432A ES424432A1 ES 424432 A1 ES424432 A1 ES 424432A1 ES 424432 A ES424432 A ES 424432A ES 424432 A ES424432 A ES 424432A ES 424432 A1 ES424432 A1 ES 424432A1
Authority
ES
Spain
Prior art keywords
formula
compounds
effect
carboxyl group
aminobenzylamines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES424432A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732318636 external-priority patent/DE2318636B2/de
Priority claimed from DE19742402989 external-priority patent/DE2402989C3/de
Priority claimed from DE19742405322 external-priority patent/DE2405322A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Priority to ES433896A priority Critical patent/ES433896A1/es
Priority to ES433897A priority patent/ES433897A1/es
Priority to ES433898A priority patent/ES433898A1/es
Priority to ES433893A priority patent/ES433893A1/es
Priority to ES433895A priority patent/ES433895A1/es
Priority to ES433891A priority patent/ES433891A1/es
Priority to ES433901A priority patent/ES433901A1/es
Priority to ES433894A priority patent/ES433894A1/es
Priority to ES433899A priority patent/ES433899A1/es
Publication of ES424432A1 publication Critical patent/ES424432A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/24—Camphidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES424432A 1973-04-13 1974-03-20 Procedimiento para la preparacion de nuevas bencilaminas. Expired ES424432A1 (es)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ES433899A ES433899A1 (es) 1974-02-05 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433894A ES433894A1 (es) 1973-04-13 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433901A ES433901A1 (es) 1974-02-05 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433898A ES433898A1 (es) 1974-02-05 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433897A ES433897A1 (es) 1974-02-05 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433896A ES433896A1 (es) 1974-02-05 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433893A ES433893A1 (es) 1973-04-13 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433895A ES433895A1 (es) 1974-02-05 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.
ES433891A ES433891A1 (es) 1973-04-13 1975-01-17 Procedimiento para la preparacion de nuevas bencilaminas.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19732318636 DE2318636B2 (de) 1973-04-13 1973-04-13 Neue benzylamine, sie enthaltende arzneimittel und verfahren zu ihrer herstellung
DE19742402989 DE2402989C3 (de) 1974-01-23 1974-01-23 Neue Benzylamine, sie enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE19742405322 DE2405322A1 (de) 1974-02-05 1974-02-05 Neue verfahren zur herstellung von benzylaminen

Publications (1)

Publication Number Publication Date
ES424432A1 true ES424432A1 (es) 1976-06-01

Family

ID=27185183

Family Applications (1)

Application Number Title Priority Date Filing Date
ES424432A Expired ES424432A1 (es) 1973-04-13 1974-03-20 Procedimiento para la preparacion de nuevas bencilaminas.

Country Status (19)

Country Link
JP (1) JPS5634582B2 (de)
AT (1) AT332375B (de)
BG (1) BG25787A3 (de)
CA (1) CA1011748A (de)
CH (2) CH609327A5 (de)
CS (1) CS188920B2 (de)
DD (1) DD113748A5 (de)
ES (1) ES424432A1 (de)
FR (1) FR2225165B1 (de)
GB (1) GB1469187A (de)
HU (1) HU167971B (de)
IE (1) IE40146B1 (de)
IL (1) IL44623A (de)
NL (1) NL7404965A (de)
NO (1) NO138250C (de)
PL (2) PL89811B1 (de)
RO (3) RO69152A (de)
SE (1) SE411749B (de)
SU (2) SU517250A3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167562B (de) * 1974-01-19 1975-11-28
DE2926472A1 (de) * 1979-06-30 1981-01-15 Thomae Gmbh Dr K Neue benzoylderivate, deren herstellung und deren verwendung als arzneimittel
DE3100575A1 (de) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benzoesaeuren, ihre herstellung und ihre verwendung als arzneimittel"
US4735959A (en) * 1981-01-10 1988-04-05 Dr. Karl Thomae Gmbh Carboxylic acid amides and pharmaceutical compositions containing them
JPS60146849A (ja) * 1984-01-09 1985-08-02 Mitsui Toatsu Chem Inc アミノベンジルアミンの製造方法
JPH0365264A (ja) * 1989-08-03 1991-03-20 Sanko Denki Seisakusho:Kk 霧化装置
DE19529431C1 (de) * 1995-08-10 1996-12-12 Boehringer Ingelheim Kg Verfahren zur Herstellung von Benzylaminderivaten
CN112279774B (zh) * 2019-07-24 2023-05-30 成都施贝康生物医药科技有限公司 二溴苄基衍生物、其立体异构体或其盐及制法和应用

Also Published As

Publication number Publication date
DD113748A5 (de) 1975-06-20
IE40146B1 (en) 1979-03-28
RO69152A (ro) 1981-01-30
JPS5012030A (de) 1975-02-07
BG25787A3 (en) 1978-12-12
SU517250A3 (ru) 1976-06-05
SE411749B (sv) 1980-02-04
NO138250B (no) 1978-04-24
SU521836A3 (ru) 1976-07-15
ATA202374A (de) 1976-01-15
RO69291A (ro) 1983-04-29
GB1469187A (en) 1977-03-30
FR2225165B1 (de) 1977-09-09
NO741350L (no) 1974-10-15
CA1011748A (en) 1977-06-07
JPS5634582B2 (de) 1981-08-11
FR2225165A1 (de) 1974-11-08
RO69291B (ro) 1983-04-30
IL44623A0 (en) 1974-06-30
HU167971B (en) 1976-01-28
NL7404965A (de) 1974-10-15
RO70260A (ro) 1980-03-15
IE40146L (en) 1974-10-13
CH609327A5 (en) 1979-02-28
CH609041A5 (en) 1979-02-15
CS188920B2 (en) 1979-03-30
AT332375B (de) 1976-09-27
NO138250C (no) 1978-08-02
PL102867B1 (pl) 1979-04-30
IL44623A (en) 1978-01-31
PL89811B1 (de) 1976-12-31

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