CH609041A5 - Process for the preparation of novel benzylamines - Google Patents

Process for the preparation of novel benzylamines

Info

Publication number
CH609041A5
CH609041A5 CH528677A CH528677A CH609041A5 CH 609041 A5 CH609041 A5 CH 609041A5 CH 528677 A CH528677 A CH 528677A CH 528677 A CH528677 A CH 528677A CH 609041 A5 CH609041 A5 CH 609041A5
Authority
CH
Switzerland
Prior art keywords
benzylamines
novel
preparation
novel benzylamines
Prior art date
Application number
CH528677A
Inventor
Johannes Dr Keck
Klaus-Reinhold Dr Noll
Helmut Dr Pieper
Gerd Dr Krueger
Sigfrid Dr Pueschmann
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732318636 external-priority patent/DE2318636B2/en
Priority claimed from DE19742402989 external-priority patent/DE2402989C3/en
Priority claimed from DE19742405322 external-priority patent/DE2405322A1/en
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CH609041A5 publication Critical patent/CH609041A5/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/24—Camphidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
CH528677A 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines CH609041A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19732318636 DE2318636B2 (en) 1973-04-13 1973-04-13 NEW BENZYLAMINES, MEDICINAL PRODUCTS AND THE METHOD OF MANUFACTURING THEM
DE19742402989 DE2402989C3 (en) 1974-01-23 1974-01-23 New benzylamines, pharmaceuticals containing them and processes for their manufacture
DE19742405322 DE2405322A1 (en) 1974-02-05 1974-02-05 NEW METHODS FOR MANUFACTURING BENZYLAMINES

Publications (1)

Publication Number Publication Date
CH609041A5 true CH609041A5 (en) 1979-02-15

Family

ID=27185183

Family Applications (2)

Application Number Title Priority Date Filing Date
CH528677A CH609041A5 (en) 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines
CH493174A CH609327A5 (en) 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH493174A CH609327A5 (en) 1973-04-13 1974-04-09 Process for the preparation of novel benzylamines

Country Status (19)

Country Link
JP (1) JPS5634582B2 (en)
AT (1) AT332375B (en)
BG (1) BG25787A3 (en)
CA (1) CA1011748A (en)
CH (2) CH609041A5 (en)
CS (1) CS188920B2 (en)
DD (1) DD113748A5 (en)
ES (1) ES424432A1 (en)
FR (1) FR2225165B1 (en)
GB (1) GB1469187A (en)
HU (1) HU167971B (en)
IE (1) IE40146B1 (en)
IL (1) IL44623A (en)
NL (1) NL7404965A (en)
NO (1) NO138250C (en)
PL (2) PL89811B1 (en)
RO (3) RO70260A (en)
SE (1) SE411749B (en)
SU (2) SU517250A3 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167562B (en) * 1974-01-19 1975-11-28
DE2926472A1 (en) * 1979-06-30 1981-01-15 Thomae Gmbh Dr K NEW BENZOYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
DE3100575A1 (en) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "NEW BENZOESAEURS, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS"
US4735959A (en) * 1981-01-10 1988-04-05 Dr. Karl Thomae Gmbh Carboxylic acid amides and pharmaceutical compositions containing them
JPS60146849A (en) * 1984-01-09 1985-08-02 Mitsui Toatsu Chem Inc Preparation of aminobenzylamine
JPH0365264A (en) * 1989-08-03 1991-03-20 Sanko Denki Seisakusho:Kk Spraying device
DE19529431C1 (en) * 1995-08-10 1996-12-12 Boehringer Ingelheim Kg Prepn. of benzylamine derivs., by redn. of corresp. nitro cpd in presence of iron@
CN112279774B (en) * 2019-07-24 2023-05-30 成都施贝康生物医药科技有限公司 Dibromobenzyl derivative, stereoisomer or salt thereof, preparation method and application

Also Published As

Publication number Publication date
NO138250C (en) 1978-08-02
PL102867B1 (en) 1979-04-30
NO741350L (en) 1974-10-15
SU517250A3 (en) 1976-06-05
HU167971B (en) 1976-01-28
SU521836A3 (en) 1976-07-15
IL44623A (en) 1978-01-31
FR2225165A1 (en) 1974-11-08
IE40146B1 (en) 1979-03-28
CA1011748A (en) 1977-06-07
FR2225165B1 (en) 1977-09-09
SE411749B (en) 1980-02-04
ES424432A1 (en) 1976-06-01
GB1469187A (en) 1977-03-30
RO69291B (en) 1983-04-30
RO69152A (en) 1981-01-30
AT332375B (en) 1976-09-27
PL89811B1 (en) 1976-12-31
RO69291A (en) 1983-04-29
NO138250B (en) 1978-04-24
NL7404965A (en) 1974-10-15
CH609327A5 (en) 1979-02-28
ATA202374A (en) 1976-01-15
JPS5634582B2 (en) 1981-08-11
DD113748A5 (en) 1975-06-20
IL44623A0 (en) 1974-06-30
RO70260A (en) 1980-03-15
CS188920B2 (en) 1979-03-30
IE40146L (en) 1974-10-13
JPS5012030A (en) 1975-02-07
BG25787A3 (en) 1978-12-12

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Legal Events

Date Code Title Description
PL Patent ceased