RO69291B - Procedeu pentru prepararea unor benzilamine - Google Patents

Procedeu pentru prepararea unor benzilamine

Info

Publication number
RO69291B
RO69291B RO82361A RO8236174A RO69291B RO 69291 B RO69291 B RO 69291B RO 82361 A RO82361 A RO 82361A RO 8236174 A RO8236174 A RO 8236174A RO 69291 B RO69291 B RO 69291B
Authority
RO
Romania
Prior art keywords
benzylamines
preparing
Prior art date
Application number
RO82361A
Other languages
English (en)
Other versions
RO69291A (ro
Inventor
Johannes Keck
Klaus Reinhold Noll
Helmut Piepper
Gerd Kruger
Sigfrid Puschmann
Original Assignee
Dr. Karl Thomae G.M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732318636 external-priority patent/DE2318636B2/de
Priority claimed from DE19742402989 external-priority patent/DE2402989C3/de
Priority claimed from DE19742405322 external-priority patent/DE2405322A1/de
Application filed by Dr. Karl Thomae G.M.B.H. filed Critical Dr. Karl Thomae G.M.B.H.
Publication of RO69291A publication Critical patent/RO69291A/ro
Publication of RO69291B publication Critical patent/RO69291B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/24—Camphidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RO82361A 1973-04-13 1974-04-09 Procedeu pentru prepararea unor benzilamine RO69291B (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19732318636 DE2318636B2 (de) 1973-04-13 1973-04-13 Neue benzylamine, sie enthaltende arzneimittel und verfahren zu ihrer herstellung
DE19742402989 DE2402989C3 (de) 1974-01-23 1974-01-23 Neue Benzylamine, sie enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE19742405322 DE2405322A1 (de) 1974-02-05 1974-02-05 Neue verfahren zur herstellung von benzylaminen

Publications (2)

Publication Number Publication Date
RO69291A RO69291A (ro) 1983-04-29
RO69291B true RO69291B (ro) 1983-04-30

Family

ID=27185183

Family Applications (3)

Application Number Title Priority Date Filing Date
RO7482360A RO70260A (ro) 1973-04-13 1974-04-09 Procedeu pentru prepararea unor benzilamine
RO82361A RO69291B (ro) 1973-04-13 1974-04-09 Procedeu pentru prepararea unor benzilamine
RO7478362A RO69152A (ro) 1973-04-13 1974-04-09 Procedeu pentru prepararea unor benzilamine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RO7482360A RO70260A (ro) 1973-04-13 1974-04-09 Procedeu pentru prepararea unor benzilamine

Family Applications After (1)

Application Number Title Priority Date Filing Date
RO7478362A RO69152A (ro) 1973-04-13 1974-04-09 Procedeu pentru prepararea unor benzilamine

Country Status (19)

Country Link
JP (1) JPS5634582B2 (ro)
AT (1) AT332375B (ro)
BG (1) BG25787A3 (ro)
CA (1) CA1011748A (ro)
CH (2) CH609327A5 (ro)
CS (1) CS188920B2 (ro)
DD (1) DD113748A5 (ro)
ES (1) ES424432A1 (ro)
FR (1) FR2225165B1 (ro)
GB (1) GB1469187A (ro)
HU (1) HU167971B (ro)
IE (1) IE40146B1 (ro)
IL (1) IL44623A (ro)
NL (1) NL7404965A (ro)
NO (1) NO138250C (ro)
PL (2) PL102867B1 (ro)
RO (3) RO70260A (ro)
SE (1) SE411749B (ro)
SU (2) SU517250A3 (ro)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167562B (ro) * 1974-01-19 1975-11-28
DE2926472A1 (de) * 1979-06-30 1981-01-15 Thomae Gmbh Dr K Neue benzoylderivate, deren herstellung und deren verwendung als arzneimittel
US4735959A (en) * 1981-01-10 1988-04-05 Dr. Karl Thomae Gmbh Carboxylic acid amides and pharmaceutical compositions containing them
DE3100575A1 (de) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benzoesaeuren, ihre herstellung und ihre verwendung als arzneimittel"
JPS60146849A (ja) * 1984-01-09 1985-08-02 Mitsui Toatsu Chem Inc アミノベンジルアミンの製造方法
JPH0365264A (ja) * 1989-08-03 1991-03-20 Sanko Denki Seisakusho:Kk 霧化装置
DE19529431C1 (de) * 1995-08-10 1996-12-12 Boehringer Ingelheim Kg Verfahren zur Herstellung von Benzylaminderivaten
CN112279774B (zh) * 2019-07-24 2023-05-30 成都施贝康生物医药科技有限公司 二溴苄基衍生物、其立体异构体或其盐及制法和应用

Also Published As

Publication number Publication date
RO70260A (ro) 1980-03-15
CH609041A5 (en) 1979-02-15
CH609327A5 (en) 1979-02-28
FR2225165A1 (ro) 1974-11-08
PL102867B1 (pl) 1979-04-30
SU521836A3 (ru) 1976-07-15
JPS5634582B2 (ro) 1981-08-11
SU517250A3 (ru) 1976-06-05
RO69152A (ro) 1981-01-30
BG25787A3 (en) 1978-12-12
IL44623A (en) 1978-01-31
JPS5012030A (ro) 1975-02-07
NO741350L (no) 1974-10-15
RO69291A (ro) 1983-04-29
IE40146B1 (en) 1979-03-28
IL44623A0 (en) 1974-06-30
ES424432A1 (es) 1976-06-01
ATA202374A (de) 1976-01-15
CS188920B2 (en) 1979-03-30
IE40146L (en) 1974-10-13
NO138250C (no) 1978-08-02
AT332375B (de) 1976-09-27
NL7404965A (ro) 1974-10-15
HU167971B (en) 1976-01-28
PL89811B1 (ro) 1976-12-31
CA1011748A (en) 1977-06-07
SE411749B (sv) 1980-02-04
NO138250B (no) 1978-04-24
DD113748A5 (ro) 1975-06-20
FR2225165B1 (ro) 1977-09-09
GB1469187A (en) 1977-03-30

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