ES399874A1 - 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation - Google Patents

1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation

Info

Publication number
ES399874A1
ES399874A1 ES399874A ES399874A ES399874A1 ES 399874 A1 ES399874 A1 ES 399874A1 ES 399874 A ES399874 A ES 399874A ES 399874 A ES399874 A ES 399874A ES 399874 A1 ES399874 A1 ES 399874A1
Authority
ES
Spain
Prior art keywords
carbon atoms
radical
halogen
phenoxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES399874A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES399874A1 publication Critical patent/ES399874A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-alcoholylaminopropanes of the general formula ** (See formula) ** where R1 means a radical with the partial formula (CH2) x- CN, (CH2) x - NH2 or (CH2) x + 1 - OH, (where x means zero or an integer from 1 to 3), COOR5 (where R5 signifies hydrogen or an alcohol radical with 1 to 4 carbon atoms), an alkenyl, alkynyl, alkenyloxy or alkynyloxy radical with 2 to 5 carbon atoms) R2 signifies halogen; R3 means hydrogen, halogen or an alcohol or alkoxy group with 1 to 4 carbon atoms; and R4 means a straight or branched chain hydroxyalkyl group with 3 to 6 carbon atoms, characterized in that a halogen atom is introduced into a compound of the general formula Ar-OCH2-CHOH-CH2-NH-R4 II in which R4 has the meanings mentioned above and Ar means the radical. ** (See formula) ** (in which R1 and R3 have the meanings mentioned above), and if desired, the compounds obtained are transformed into their salts by the addition of physiologically compatible acids or esters. (Machine-translation by Google Translate, not legally binding)
ES399874A 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation Expired ES399874A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702048838 DE2048838A1 (en) 1970-10-05 1970-10-05 New 1 phenoxy 2 hydroxy 3 hydroxyal kylaminopropane and process for their manufacture

Publications (1)

Publication Number Publication Date
ES399874A1 true ES399874A1 (en) 1975-07-01

Family

ID=5784228

Family Applications (8)

Application Number Title Priority Date Filing Date
ES395671A Expired ES395671A1 (en) 1970-10-05 1971-10-04 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399873A Expired ES399873A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399874A Expired ES399874A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399872A Expired ES399872A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399869A Expired ES399869A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399868A Expired ES399868A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399870A Expired ES399870A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399871A Expired ES399871A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES395671A Expired ES395671A1 (en) 1970-10-05 1971-10-04 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399873A Expired ES399873A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation

Family Applications After (5)

Application Number Title Priority Date Filing Date
ES399872A Expired ES399872A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399869A Expired ES399869A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399868A Expired ES399868A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399870A Expired ES399870A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation
ES399871A Expired ES399871A1 (en) 1970-10-05 1972-02-17 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation

Country Status (26)

Country Link
JP (1) JPS5710097B1 (en)
AT (10) AT318564B (en)
AU (1) AU469119B2 (en)
BE (1) BE773472A (en)
BG (8) BG20100A3 (en)
CA (1) CA1008866A (en)
CH (11) CH583685A5 (en)
CS (2) CS172932B2 (en)
DE (1) DE2048838A1 (en)
DK (1) DK130958B (en)
ES (8) ES395671A1 (en)
FI (1) FI55491C (en)
FR (1) FR2110230B1 (en)
GB (1) GB1364280A (en)
HU (1) HU163226B (en)
IE (1) IE35693B1 (en)
IL (1) IL37830A (en)
NL (1) NL174249C (en)
NO (1) NO132835C (en)
PH (1) PH9959A (en)
PL (10) PL84225B1 (en)
RO (8) RO62357A (en)
SE (1) SE383631B (en)
SU (2) SU419024A3 (en)
YU (2) YU35576B (en)
ZA (1) ZA716643B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4055658A (en) * 1976-05-17 1977-10-25 Mead Johnson & Company Cyanomethylphenethanolamines
US4454154A (en) * 1981-06-23 1984-06-12 American Hospital Supply Corporation Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents
DE3248835A1 (en) * 1981-06-23 1983-06-30 American Hospital Supply Corp COMPOSITIONS FOR TREATING GLAUCOMA
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
DE4422707A1 (en) * 1994-06-29 1996-01-04 Hoechst Ag Process for dyeing aminated cellulose / polyester blends with fiber-reactive disperse dyes
JP4934287B2 (en) * 2005-04-05 2012-05-16 花王株式会社 Whitening agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD45360A (en) *
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives

Also Published As

Publication number Publication date
ES399868A1 (en) 1975-06-16
DK130958B (en) 1975-05-12
SU419024A3 (en) 1974-03-05
AT318569B (en) 1974-10-25
FI55491C (en) 1979-08-10
AT318567B (en) 1974-10-25
JPS5710097B1 (en) 1982-02-24
CH564515A5 (en) 1975-07-31
ES399870A1 (en) 1975-07-16
IE35693L (en) 1972-04-05
ES399872A1 (en) 1975-07-01
RO62313A (en) 1977-08-15
AT318566B (en) 1974-10-25
NO132835C (en) 1976-01-14
FR2110230A1 (en) 1972-06-02
FR2110230B1 (en) 1975-03-14
CH564516A5 (en) 1975-07-31
RO62355A (en) 1977-10-15
BG18857A3 (en) 1975-03-20
ES399869A1 (en) 1975-06-16
PH9959A (en) 1976-06-14
PL84224B1 (en) 1976-03-31
PL84212B1 (en) 1976-03-31
BG18858A3 (en) 1975-03-20
CH563342A5 (en) 1975-06-30
IE35693B1 (en) 1976-04-28
BG19134A3 (en) 1975-04-30
RO62267A (en) 1978-01-15
RO62359A (en) 1977-11-15
AU3418271A (en) 1973-04-12
CH587227A5 (en) 1977-04-29
NL174249C (en) 1984-05-16
SU677649A3 (en) 1979-07-30
BG19133A3 (en) 1975-04-30
PL82037B1 (en) 1975-10-31
RO61540A (en) 1977-02-15
DK130958C (en) 1975-10-13
AT318571B (en) 1974-10-25
PL84276B1 (en) 1976-03-31
BE773472A (en) 1972-04-04
ES395671A1 (en) 1974-10-16
PL84225B1 (en) 1976-03-31
PL84267B1 (en) 1976-03-31
ES399873A1 (en) 1975-07-01
BG20100A3 (en) 1975-10-30
FI55491B (en) 1979-04-30
IL37830A (en) 1975-03-13
CH584185A5 (en) 1977-01-31
HU163226B (en) 1973-07-28
AT318572B (en) 1974-10-25
BG20338A3 (en) 1975-11-05
SE383631B (en) 1976-03-22
RO62357A (en) 1977-10-15
AT318565B (en) 1974-10-25
CH564507A5 (en) 1975-07-31
DE2048838A1 (en) 1972-04-06
YU23679A (en) 1980-10-31
IL37830A0 (en) 1971-12-29
YU35577B (en) 1981-04-30
YU250571A (en) 1980-10-31
BG18859A3 (en) 1975-03-20
CH583685A5 (en) 1977-01-14
AT318561B (en) 1974-10-25
PL84227B1 (en) 1976-03-31
GB1364280A (en) 1974-08-21
AT318568B (en) 1974-10-25
CA1008866A (en) 1977-04-19
YU35576B (en) 1981-04-30
ES399871A1 (en) 1975-06-16
CH583686A5 (en) 1977-01-14
RO62358A (en) 1978-04-15
CH563341A5 (en) 1975-06-30
NL174249B (en) 1983-12-16
PL84226B1 (en) 1976-03-31
CS172950B2 (en) 1977-01-28
PL84223B1 (en) 1976-03-31
AU469119B2 (en) 1976-02-05
CS172932B2 (en) 1977-01-28
AT318570B (en) 1974-10-25
CH583687A5 (en) 1977-01-14
NL7113581A (en) 1972-04-07
NO132835B (en) 1975-10-06
RO62356A (en) 1977-08-15
PL84396B1 (en) 1976-03-31
AT318564B (en) 1974-10-25
BG19793A3 (en) 1975-10-10
CH587223A5 (en) 1977-04-29
ZA716643B (en) 1973-06-27

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