ES373698A1 - Un procedimiento para la preparacion de 5-nr1r2-6-cloro - 1h-imidazo (4,5-b) pirazin-2-onas. - Google Patents
Un procedimiento para la preparacion de 5-nr1r2-6-cloro - 1h-imidazo (4,5-b) pirazin-2-onas.Info
- Publication number
- ES373698A1 ES373698A1 ES373698A ES373698A ES373698A1 ES 373698 A1 ES373698 A1 ES 373698A1 ES 373698 A ES373698 A ES 373698A ES 373698 A ES373698 A ES 373698A ES 373698 A1 ES373698 A1 ES 373698A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- hydrogen atom
- amino
- alkyl
- diamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77747968A | 1968-11-20 | 1968-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES373698A1 true ES373698A1 (es) | 1972-02-01 |
Family
ID=25110373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES373698A Expired ES373698A1 (es) | 1968-11-20 | 1969-11-19 | Un procedimiento para la preparacion de 5-nr1r2-6-cloro - 1h-imidazo (4,5-b) pirazin-2-onas. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3549633A (es) |
| AT (1) | AT291250B (es) |
| BR (1) | BR6914169D0 (es) |
| CH (1) | CH518957A (es) |
| ES (1) | ES373698A1 (es) |
| FR (1) | FR2070653A1 (es) |
| GB (1) | GB1242625A (es) |
| NL (1) | NL6915958A (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4053577A (en) * | 1972-02-18 | 1977-10-11 | Tioxide Group Limited | Process for the gaseous phase production of metal oxide particles |
| GR74944B (es) * | 1980-07-02 | 1984-07-12 | Merck & Co Inc | |
| ES2568260T3 (es) | 2010-11-16 | 2016-04-28 | Acetylon Pharmaceuticals, Inc. | Compuestos de pirimidin hidroxi amida como inhibidores de proteína desacetilasa y métodos de uso de los mismos |
| US9403779B2 (en) | 2013-10-08 | 2016-08-02 | Acetylon Pharmaceuticals, Inc. | Combinations of histone deacetylase inhibitors and either Her2 inhibitors or PI3K inhibitors |
| ES2862126T3 (es) | 2013-10-10 | 2021-10-07 | Acetylon Pharmaceuticals Inc | Compuestos de pirimidín-hidroxiamida como inhibidores de histona desacetilasa |
| EP4137135B1 (en) | 2013-10-24 | 2024-06-05 | Mayo Foundation for Medical Education and Research | Treatment of polycystic diseases with an hdac6 inhibitor |
| JP6535670B2 (ja) | 2013-12-03 | 2019-06-26 | アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | ヒストンデアセチラーゼ阻害剤と免疫調節薬の組合せ |
| US9464073B2 (en) | 2014-02-26 | 2016-10-11 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors |
| US9833466B2 (en) | 2014-07-07 | 2017-12-05 | Acetylon Pharmaceuticals, Inc. | Treatment of leukemia with histone deacetylase inhibitors |
| JP2017537164A (ja) | 2014-12-05 | 2017-12-14 | ユニヴァーシティ・オブ・モデナ・アンド・レッジョ・エミリア | リンパ腫の治療に使用されるヒストン脱アセチル化酵素阻害剤とベンダムスチンとの組み合わせ |
| US10272084B2 (en) | 2015-06-01 | 2019-04-30 | Regenacy Pharmaceuticals, Llc | Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy |
| WO2017184774A1 (en) | 2016-04-19 | 2017-10-26 | Acetylon Pharmaceuticals, Inc. | Hdac inhibitors, alone or in combination with btk inhibitors, for treating chronic lymphocytic leukemia |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE651730A (es) * | 1962-10-30 | 1965-02-12 | ||
| US3361748A (en) * | 1965-11-22 | 1968-01-02 | Merck & Co Inc | Process for the preparation of pteridinones |
-
1968
- 1968-11-20 US US777479A patent/US3549633A/en not_active Expired - Lifetime
-
1969
- 1969-10-22 NL NL6915958A patent/NL6915958A/xx unknown
- 1969-11-13 CH CH1690669A patent/CH518957A/de not_active IP Right Cessation
- 1969-11-13 BR BR214169/69A patent/BR6914169D0/pt unknown
- 1969-11-17 GB GB56182/69A patent/GB1242625A/en not_active Expired
- 1969-11-19 ES ES373698A patent/ES373698A1/es not_active Expired
- 1969-11-19 AT AT1082669A patent/AT291250B/de not_active IP Right Cessation
- 1969-11-20 FR FR6939940A patent/FR2070653A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NL6915958A (es) | 1970-05-22 |
| BR6914169D0 (pt) | 1973-02-22 |
| US3549633A (en) | 1970-12-22 |
| FR2070653A1 (es) | 1971-09-17 |
| CH518957A (de) | 1972-02-15 |
| AT291250B (de) | 1971-07-12 |
| GB1242625A (en) | 1971-08-11 |
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