KR790000508B1 - Process for preparation of n,n'-disubstituted amidines - Google Patents

Process for preparation of n,n'-disubstituted amidines

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Publication number
KR790000508B1
KR790000508B1 KR7403183A KR740003183A KR790000508B1 KR 790000508 B1 KR790000508 B1 KR 790000508B1 KR 7403183 A KR7403183 A KR 7403183A KR 740003183 A KR740003183 A KR 740003183A KR 790000508 B1 KR790000508 B1 KR 790000508B1
Authority
KR
South Korea
Prior art keywords
org
give
solvent
acid salt
amidines
Prior art date
Application number
KR7403183A
Other languages
Korean (ko)
Inventor
K Hayano
H Hamakawa
S Kobari
T Simicu
K Huzimoto
T Massuta
Original Assignee
Tooyo Ccoocoo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tooyo Ccoocoo Co Ltd filed Critical Tooyo Ccoocoo Co Ltd
Priority to KR7403183A priority Critical patent/KR790000508B1/en
Application granted granted Critical
Publication of KR790000508B1 publication Critical patent/KR790000508B1/en

Links

Abstract

Less-toxic N, N'-disubstituted amidines (I; R= Me, R2=substituted phenyl) with antiinflammatory action were manufd. Imino compd. was reacted with amines in org. solvent to give tautomeric amidines in free base or hydrohalo acid salt mixt. The products were dissolved in hydrophilic org. solvent added HCI and washed with non-hydrophilic org. solvent to give acid salt. The acid solt was treated with alk. and extd. with obtain free base form. The amidine base was treated with org. or inorg. acid to give acid salt.
KR7403183A 1974-07-27 1974-07-27 Process for preparation of n,n'-disubstituted amidines KR790000508B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR7403183A KR790000508B1 (en) 1974-07-27 1974-07-27 Process for preparation of n,n'-disubstituted amidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR7403183A KR790000508B1 (en) 1974-07-27 1974-07-27 Process for preparation of n,n'-disubstituted amidines

Publications (1)

Publication Number Publication Date
KR790000508B1 true KR790000508B1 (en) 1979-05-29

Family

ID=19200325

Family Applications (1)

Application Number Title Priority Date Filing Date
KR7403183A KR790000508B1 (en) 1974-07-27 1974-07-27 Process for preparation of n,n'-disubstituted amidines

Country Status (1)

Country Link
KR (1) KR790000508B1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022139594A1 (en) 2020-12-23 2022-06-30 Klingelberg Products As Amides and solvent free method for their manufacture

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022139594A1 (en) 2020-12-23 2022-06-30 Klingelberg Products As Amides and solvent free method for their manufacture
WO2022139593A1 (en) 2020-12-23 2022-06-30 Klingelberg Products As Amidines and solvent free method for their manufacture

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