KR790000508B1 - Process for preparation of n,n'-disubstituted amidines - Google Patents
Process for preparation of n,n'-disubstituted amidinesInfo
- Publication number
- KR790000508B1 KR790000508B1 KR7403183A KR740003183A KR790000508B1 KR 790000508 B1 KR790000508 B1 KR 790000508B1 KR 7403183 A KR7403183 A KR 7403183A KR 740003183 A KR740003183 A KR 740003183A KR 790000508 B1 KR790000508 B1 KR 790000508B1
- Authority
- KR
- South Korea
- Prior art keywords
- org
- give
- solvent
- acid salt
- amidines
- Prior art date
Links
Abstract
Less-toxic N, N'-disubstituted amidines (I; R= Me, R2=substituted phenyl) with antiinflammatory action were manufd. Imino compd. was reacted with amines in org. solvent to give tautomeric amidines in free base or hydrohalo acid salt mixt. The products were dissolved in hydrophilic org. solvent added HCI and washed with non-hydrophilic org. solvent to give acid salt. The acid solt was treated with alk. and extd. with obtain free base form. The amidine base was treated with org. or inorg. acid to give acid salt.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR7403183A KR790000508B1 (en) | 1974-07-27 | 1974-07-27 | Process for preparation of n,n'-disubstituted amidines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR7403183A KR790000508B1 (en) | 1974-07-27 | 1974-07-27 | Process for preparation of n,n'-disubstituted amidines |
Publications (1)
Publication Number | Publication Date |
---|---|
KR790000508B1 true KR790000508B1 (en) | 1979-05-29 |
Family
ID=19200325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR7403183A KR790000508B1 (en) | 1974-07-27 | 1974-07-27 | Process for preparation of n,n'-disubstituted amidines |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR790000508B1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022139594A1 (en) | 2020-12-23 | 2022-06-30 | Klingelberg Products As | Amides and solvent free method for their manufacture |
-
1974
- 1974-07-27 KR KR7403183A patent/KR790000508B1/en active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022139594A1 (en) | 2020-12-23 | 2022-06-30 | Klingelberg Products As | Amides and solvent free method for their manufacture |
WO2022139593A1 (en) | 2020-12-23 | 2022-06-30 | Klingelberg Products As | Amidines and solvent free method for their manufacture |
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