CH518957A - Verfahren zur Herstellung von 5-Amino (oder substituierten Amino)-6-chlor-1H-imidazo(4,5-b)pyrazin-2-onen - Google Patents
Verfahren zur Herstellung von 5-Amino (oder substituierten Amino)-6-chlor-1H-imidazo(4,5-b)pyrazin-2-onenInfo
- Publication number
- CH518957A CH518957A CH1690669A CH1690669A CH518957A CH 518957 A CH518957 A CH 518957A CH 1690669 A CH1690669 A CH 1690669A CH 1690669 A CH1690669 A CH 1690669A CH 518957 A CH518957 A CH 518957A
- Authority
- CH
- Switzerland
- Prior art keywords
- amino
- pyrazin
- imidazo
- chloro
- ones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77747968A | 1968-11-20 | 1968-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH518957A true CH518957A (de) | 1972-02-15 |
Family
ID=25110373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1690669A CH518957A (de) | 1968-11-20 | 1969-11-13 | Verfahren zur Herstellung von 5-Amino (oder substituierten Amino)-6-chlor-1H-imidazo(4,5-b)pyrazin-2-onen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3549633A (de) |
| AT (1) | AT291250B (de) |
| BR (1) | BR6914169D0 (de) |
| CH (1) | CH518957A (de) |
| ES (1) | ES373698A1 (de) |
| FR (1) | FR2070653A1 (de) |
| GB (1) | GB1242625A (de) |
| NL (1) | NL6915958A (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4053577A (en) * | 1972-02-18 | 1977-10-11 | Tioxide Group Limited | Process for the gaseous phase production of metal oxide particles |
| GR74944B (de) * | 1980-07-02 | 1984-07-12 | Merck & Co Inc | |
| US8614223B2 (en) | 2010-11-16 | 2013-12-24 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof |
| US9403779B2 (en) | 2013-10-08 | 2016-08-02 | Acetylon Pharmaceuticals, Inc. | Combinations of histone deacetylase inhibitors and either Her2 inhibitors or PI3K inhibitors |
| EP3055299B1 (de) | 2013-10-10 | 2021-01-06 | Acetylon Pharmaceuticals, Inc. | Pyrimidinhydroxyamidverbindungen als histondeacetylaseinhibitoren |
| EP3060217B1 (de) | 2013-10-24 | 2022-06-08 | Mayo Foundation for Medical Education and Research | Behandlung polyzystischer erkrankungen mit einem hdac6-hemmer |
| ES2806258T3 (es) | 2013-12-03 | 2021-02-17 | Acetylon Pharmaceuticals Inc | Combinaciones de inhibidores de histona desacetilasa y fármacos inmunomoduladores |
| US9464073B2 (en) | 2014-02-26 | 2016-10-11 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors |
| EA201790142A1 (ru) | 2014-07-07 | 2017-07-31 | Эситайлон Фармасьютикалз, Инк. | Лечение лейкоза ингибиторами гистондеацетилазы |
| CN107438436A (zh) | 2014-12-05 | 2017-12-05 | 摩德纳和雷焦艾米利亚大学 | 用于治疗淋巴瘤的组蛋白脱乙酰酶抑制剂和苯达莫司汀的组合 |
| US10272084B2 (en) | 2015-06-01 | 2019-04-30 | Regenacy Pharmaceuticals, Llc | Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy |
| JP2019515909A (ja) | 2016-04-19 | 2019-06-13 | アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 慢性リンパ性白血病の治療を目的とするｈｄａｃ阻害剤単独またはｂｔｋ阻害剤との配合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE651729A (de) * | 1962-10-30 | 1965-02-12 | ||
| US3361748A (en) * | 1965-11-22 | 1968-01-02 | Merck & Co Inc | Process for the preparation of pteridinones |
-
1968
- 1968-11-20 US US777479A patent/US3549633A/en not_active Expired - Lifetime
-
1969
- 1969-10-22 NL NL6915958A patent/NL6915958A/xx unknown
- 1969-11-13 CH CH1690669A patent/CH518957A/de not_active IP Right Cessation
- 1969-11-13 BR BR214169/69A patent/BR6914169D0/pt unknown
- 1969-11-17 GB GB56182/69A patent/GB1242625A/en not_active Expired
- 1969-11-19 ES ES373698A patent/ES373698A1/es not_active Expired
- 1969-11-19 AT AT1082669A patent/AT291250B/de not_active IP Right Cessation
- 1969-11-20 FR FR6939940A patent/FR2070653A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BR6914169D0 (pt) | 1973-02-22 |
| FR2070653A1 (de) | 1971-09-17 |
| GB1242625A (en) | 1971-08-11 |
| AT291250B (de) | 1971-07-12 |
| US3549633A (en) | 1970-12-22 |
| ES373698A1 (es) | 1972-02-01 |
| NL6915958A (de) | 1970-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |