ES2961352T3 - Procedimiento de detección óptica de un movimiento en una muestra biológica con extensión espacial - Google Patents

Procedimiento de detección óptica de un movimiento en una muestra biológica con extensión espacial Download PDF

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Publication number
ES2961352T3
ES2961352T3 ES16708082T ES16708082T ES2961352T3 ES 2961352 T3 ES2961352 T3 ES 2961352T3 ES 16708082 T ES16708082 T ES 16708082T ES 16708082 T ES16708082 T ES 16708082T ES 2961352 T3 ES2961352 T3 ES 2961352T3
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Prior art keywords
sample
detector
light
radiation
radiation source
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English (en)
Spanish (es)
Inventor
Heiko Zimmermann
Frank Stracke
Harzic Ronan Le
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Saarland University
Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung eV
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Saarland University
Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung eV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01P—MEASURING LINEAR OR ANGULAR SPEED, ACCELERATION, DECELERATION, OR SHOCK; INDICATING PRESENCE, ABSENCE, OR DIRECTION, OF MOVEMENT
    • G01P13/00—Indicating or recording presence, absence, or direction, of movement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21—Polarisation-affecting properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4788—Diffraction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4788—Diffraction
    • G01N2021/479—Speckle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4792—Polarisation of scatter light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility

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  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
ES16708082T 2015-03-06 2016-03-02 Procedimiento de detección óptica de un movimiento en una muestra biológica con extensión espacial Active ES2961352T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102015003019.1A DE102015003019A1 (de) 2015-03-06 2015-03-06 Verfahren und Vorrichtung zur optischen Detektion einer Bewegung in einer biologischen Probe mit räumlicher Ausdehnung
PCT/EP2016/000377 WO2016142043A1 (de) 2015-03-06 2016-03-02 Verfahren und vorrichtung zur optischen detektion einer bewegung in einer biologischen probe mit räumlicher ausdehnung

Publications (1)

Publication Number Publication Date
ES2961352T3 true ES2961352T3 (es) 2024-03-11

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
ES16708082T Active ES2961352T3 (es) 2015-03-06 2016-03-02 Procedimiento de detección óptica de un movimiento en una muestra biológica con extensión espacial
ES23182756T Active ES3066030T3 (en) 2015-03-06 2016-03-02 Method for optical detection of a movement in a biological sample with a spatial extent

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES23182756T Active ES3066030T3 (en) 2015-03-06 2016-03-02 Method for optical detection of a movement in a biological sample with a spatial extent

Country Status (8)

Country Link
US (1) US10488400B2 (enExample)
EP (2) EP4242637B1 (enExample)
JP (1) JP6851328B2 (enExample)
KR (1) KR20170140182A (enExample)
CN (1) CN107430064B (enExample)
DE (1) DE102015003019A1 (enExample)
ES (2) ES2961352T3 (enExample)
WO (1) WO2016142043A1 (enExample)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10088660B2 (en) 2017-02-10 2018-10-02 Amgen Inc. Imaging system for counting and sizing particles in fluid-filled vessels
KR102689739B1 (ko) * 2017-02-10 2024-07-29 암겐 인코포레이티드 유체-충진된 용기 내 입자를 계수 및 사이징하기 위한 화상화 시스템
US12026900B2 (en) 2017-12-27 2024-07-02 Cllag GmbH International Hyperspectral imaging in a light deficient environment
DE102018111033A1 (de) * 2018-05-08 2019-11-14 Byonoy Gmbh Transmissionsvorrichtung zur Untersuchung von Proben in Kavitäten einer Mikrotiterplatte und Verfahren zum Untersuchen von Proben in Kavitäten einer Mikrotiterplatte mittels Transmission
US11213194B2 (en) 2019-06-20 2022-01-04 Cilag Gmbh International Optical fiber waveguide in an endoscopic system for hyperspectral, fluorescence, and laser mapping imaging
US11624830B2 (en) 2019-06-20 2023-04-11 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for laser mapping imaging
US11700995B2 (en) 2019-06-20 2023-07-18 Cilag Gmbh International Speckle removal in a pulsed fluorescence imaging system
US12013496B2 (en) 2019-06-20 2024-06-18 Cilag Gmbh International Noise aware edge enhancement in a pulsed laser mapping imaging system
US11944273B2 (en) 2019-06-20 2024-04-02 Cilag Gmbh International Fluorescence videostroboscopy of vocal cords
US11758256B2 (en) 2019-06-20 2023-09-12 Cilag Gmbh International Fluorescence imaging in a light deficient environment
US11793399B2 (en) 2019-06-20 2023-10-24 Cilag Gmbh International Super resolution and color motion artifact correction in a pulsed hyperspectral imaging system
US11898909B2 (en) 2019-06-20 2024-02-13 Cilag Gmbh International Noise aware edge enhancement in a pulsed fluorescence imaging system
US12126887B2 (en) 2019-06-20 2024-10-22 Cilag Gmbh International Hyperspectral and fluorescence imaging with topology laser scanning in a light deficient environment
US11716543B2 (en) 2019-06-20 2023-08-01 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for fluorescence imaging
US10952619B2 (en) 2019-06-20 2021-03-23 Ethicon Llc Hyperspectral and fluorescence imaging and topology laser mapping with minimal area monolithic image sensor
US11134832B2 (en) 2019-06-20 2021-10-05 Cilag Gmbh International Image rotation in an endoscopic hyperspectral, fluorescence, and laser mapping imaging system
US11931009B2 (en) 2019-06-20 2024-03-19 Cilag Gmbh International Offset illumination of a scene using multiple emitters in a hyperspectral imaging system
US11389066B2 (en) 2019-06-20 2022-07-19 Cilag Gmbh International Noise aware edge enhancement in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11671691B2 (en) 2019-06-20 2023-06-06 Cilag Gmbh International Image rotation in an endoscopic laser mapping imaging system
US11187658B2 (en) 2019-06-20 2021-11-30 Cilag Gmbh International Fluorescence imaging with fixed pattern noise cancellation
US11012599B2 (en) 2019-06-20 2021-05-18 Ethicon Llc Hyperspectral imaging in a light deficient environment
US12440085B2 (en) 2019-06-20 2025-10-14 Cilag Gmbh International Image synchronization without input clock and data transmission clock in a pulsed laser mapping imaging system
US11141052B2 (en) 2019-06-20 2021-10-12 Cilag Gmbh International Image rotation in an endoscopic fluorescence imaging system
US20200397245A1 (en) 2019-06-20 2020-12-24 Ethicon Llc Minimizing image sensor input/output in a pulsed fluorescence imaging system
US11903563B2 (en) 2019-06-20 2024-02-20 Cilag Gmbh International Offset illumination of a scene using multiple emitters in a fluorescence imaging system
US11516387B2 (en) 2019-06-20 2022-11-29 Cilag Gmbh International Image synchronization without input clock and data transmission clock in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11337596B2 (en) 2019-06-20 2022-05-24 Cilag Gmbh International Controlling integral energy of a laser pulse in a fluorescence imaging system
US11674848B2 (en) 2019-06-20 2023-06-13 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for hyperspectral imaging
US11516388B2 (en) 2019-06-20 2022-11-29 Cilag Gmbh International Pulsed illumination in a fluorescence imaging system
US12007550B2 (en) 2019-06-20 2024-06-11 Cilag Gmbh International Driving light emissions according to a jitter specification in a spectral imaging system
US11925328B2 (en) 2019-06-20 2024-03-12 Cilag Gmbh International Noise aware edge enhancement in a pulsed hyperspectral imaging system
US20200397239A1 (en) 2019-06-20 2020-12-24 Ethicon Llc Offset illumination of a scene using multiple emitters in a fluorescence imaging system
US11360028B2 (en) 2019-06-20 2022-06-14 Cilag Gmbh International Super resolution and color motion artifact correction in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11622094B2 (en) 2019-06-20 2023-04-04 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for fluorescence imaging
US11457154B2 (en) 2019-06-20 2022-09-27 Cilag Gmbh International Speckle removal in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11237270B2 (en) 2019-06-20 2022-02-01 Cilag Gmbh International Hyperspectral, fluorescence, and laser mapping imaging with fixed pattern noise cancellation
US11550057B2 (en) 2019-06-20 2023-01-10 Cilag Gmbh International Offset illumination of a scene using multiple emitters in a fluorescence imaging system
JP7403549B2 (ja) 2019-09-26 2023-12-22 京セラ株式会社 細胞検出装置および細胞検出方法
US12599349B2 (en) 2020-06-15 2026-04-14 Arion Diagnostics, Inc. Determining a therapy efficacy
US12588883B2 (en) 2020-06-15 2026-03-31 Eosdx Inc. X-ray system and method for tissue structural analysis and imaging
US12544025B2 (en) 2020-06-15 2026-02-10 Arion Diagnostics, Inc. Determining a biological tissue structural marker for diagnosis of a disease
WO2021257457A1 (en) 2020-06-15 2021-12-23 Bragg Analytics, Inc. Diffraction-based global in vitro diagnostic system
US11607188B2 (en) 2020-06-15 2023-03-21 Eosdx Inc. Diffractometer-based global in situ diagnostic system
US12642498B2 (en) 2020-06-15 2026-06-02 Eosdx Inc. X-ray system and method for tissue structural analysis and imaging
DE102023200837A1 (de) * 2023-02-02 2024-08-08 Carl Zeiss Ag Probengefäß zur Kultivierung biologischer Proben, Vorrichtung zu dessen Betrieb und Mikroskop
US12706215B2 (en) 2023-11-02 2026-08-11 Eosdx Inc. Diagnostic systems and methods with global data center and local autonomous cell
GB2642533A (en) 2024-07-12 2026-01-14 Eosdx Uk Ltd Tissue diffractometer for determining a diagnostic indicator
CN121954232B (zh) * 2026-04-01 2026-07-17 南平博瑞医学检验所有限公司 获取细菌样品光学指纹的多波段偏振时序辐射测量方法

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54109488A (en) * 1978-02-08 1979-08-28 Fuji Photo Optical Co Ltd Analyzing method and device of optically scattered image information
DE7836339U1 (de) * 1978-12-07 1981-07-16 Kaufmann, Raimund, Dr., 4005 Meerbusch Vorrichtung zur bestimmung der geschwindigkeit von in einer fluessigkeit bewegten teilchen
JPS6259841A (ja) * 1985-09-10 1987-03-16 Res Dev Corp Of Japan 直線偏光を用いる免疫反応の測定方法および装置
JPS62116263A (ja) * 1985-11-15 1987-05-27 Olympus Optical Co Ltd 直線偏光の多重散乱を用いる免疫反応の測定方法および装置
JPH0623749B2 (ja) * 1986-03-10 1994-03-30 新技術事業団 毒素、薬剤による細胞損傷の新しい分光測定による検査法
JP2949286B2 (ja) * 1987-08-26 1999-09-13 松下電工株式会社 減光式二酸化炭素濃度感知器
EP0359681B1 (en) 1988-09-15 1995-11-08 The Board Of Trustees Of The University Of Arkansas Characterization of particles by modulated dynamic light scattering
US5061075A (en) 1989-08-07 1991-10-29 Alfano Robert R Optical method and apparatus for diagnosing human spermatozoa
US6671540B1 (en) * 1990-08-10 2003-12-30 Daryl W. Hochman Methods and systems for detecting abnormal tissue using spectroscopic techniques
DE4215908A1 (de) * 1992-05-14 1993-11-18 Ubbo Prof Dr Ricklefs Optische Einrichtung zur Bestimmung der Größe von Partikeln
US5627308A (en) * 1995-05-31 1997-05-06 Dahneke; Barton E. Method and apparatus for measuring motion of a suspended particle or a suspending fluid
US6096510A (en) * 1995-10-04 2000-08-01 Cytoscan Sciences, Llc Methods and systems for assessing biological materials using optical detection techniques
JP4169827B2 (ja) * 1997-05-28 2008-10-22 ミクロナス ゲーエムベーハー 測定装置
US20060105357A1 (en) * 1998-02-18 2006-05-18 Myomics, Inc. Tissue sensor and uses thereof
DE19836183A1 (de) * 1998-08-03 1999-03-18 Gimsa Jan Priv Doz Dr Verfahren und Vorrichtung zur räumlich (nm) und zeitlich (ms) aufgelösten Verfolgung der Bewegung mikroskopischer und submikroskopischer Objekte in mikroskopischen Volumina
DE19940752A1 (de) * 1998-08-28 2000-04-27 Febit Ferrarius Biotech Gmbh Verfahren zur Herstellung eines mit biologisch oder chemisch funktionellen Materialien beschichteten Trägers (BioChip)
US6100976A (en) * 1998-09-21 2000-08-08 The Board Of Regents For Oklahoma State University Method and apparatus for fiber optic multiple scattering suppression
GB2361772B (en) * 2000-04-29 2004-05-19 Malvern Instr Ltd Mobility and effects arising from surface charge
JP4384344B2 (ja) * 2000-08-09 2009-12-16 拓之 今野 レーザ反射光による粒状斑点模様を利用した血液凝固時間測定方法とその装置
DE10041596A1 (de) * 2000-08-24 2002-03-21 Cellcontrol Biomedical Lab Gmb Vorrichtung und Verfahren zum ortsaufgelösten Untersuchen vernetzter Zellen und/oder Zellsystemen und Verwendung für die Wirkstoffuntersuchung
JP4334899B2 (ja) * 2003-02-25 2009-09-30 大塚電子株式会社 電気泳動速度測定装置
GB0307756D0 (en) * 2003-04-03 2003-05-07 Suisse Electronique Microtech Measuring the concentration and motility of light scattering particles
DE102006003877B4 (de) * 2005-12-09 2007-10-31 Diehl Bgt Defence Gmbh & Co. Kg Vibrometer
EP2079363B1 (en) * 2006-10-30 2020-06-10 Elfi-Tech Ltd Method for in vivo measurement of biological parameters
JP5024935B2 (ja) * 2007-01-16 2012-09-12 富士フイルム株式会社 光透過性部材の欠陥検出装置及び方法
GB0701201D0 (en) * 2007-01-22 2007-02-28 Cancer Rec Tech Ltd Cell mapping and tracking
US8821799B2 (en) * 2007-01-26 2014-09-02 Palo Alto Research Center Incorporated Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity
ES2401640T3 (es) 2008-09-22 2013-04-23 University Of Zurich Prorektorat Forschung Placa para gotas en suspensión
CN201311392Y (zh) * 2008-12-11 2009-09-16 成都恩普生医疗科技有限公司 一种基于led冷光源的酶标仪光路检测系统
ES2892342T3 (es) * 2009-01-08 2022-02-03 It Is International Ltd Sistema óptico para detectar la luz de reacciones en cadena de la polimerasa
US8702942B2 (en) * 2010-12-17 2014-04-22 Malvern Instruments, Ltd. Laser doppler electrophoresis using a diffusion barrier
JP5883233B2 (ja) * 2011-03-16 2016-03-09 英光 古川 走査型顕微光散乱測定解析装置および光散乱解析方法
US8772039B2 (en) * 2011-05-26 2014-07-08 The General Hospital Corporation Optical thromboelastography system and method for evaluation of blood coagulation metrics
DE102011085599B3 (de) 2011-11-02 2012-12-13 Polytec Gmbh Vorrichtung und Verfahren zur interferometrischen Vermessung eines Objekts
DE112012004591T5 (de) * 2011-11-02 2014-09-04 Hamamatsu Photonics K.K. Beobachtungsvorrichtung
DE102012016122A1 (de) * 2012-08-15 2014-02-20 Westfälische Wilhelms-Universität Münster Verfahren und Vorrichtung zur Erfassung wenigsten eines Tieres
JP6076111B2 (ja) 2013-02-07 2017-02-08 浜松ホトニクス株式会社 塊状細胞評価方法および塊状細胞評価装置
DE102013211885A1 (de) 2013-06-24 2014-12-24 Siemens Aktiengesellschaft Partikeldetektor und Verfahren zur Detektion von Partikeln
DE202014004218U1 (de) * 2014-05-19 2014-05-28 Particle Metrix Gmbh Vorrichtung der Partikel Tracking Analyse mit Hilfe von Streulicht (PTA) und zur Erfassung und Charakterisierung von Partikeln in Flüssigkeiten aller Art in der Größenordnung von Nanometern

Also Published As

Publication number Publication date
JP6851328B2 (ja) 2021-03-31
JP2018515787A (ja) 2018-06-14
EP3265779B1 (de) 2023-08-09
KR20170140182A (ko) 2017-12-20
US10488400B2 (en) 2019-11-26
WO2016142043A1 (de) 2016-09-15
EP3265779C0 (de) 2023-08-09
EP3265779A1 (de) 2018-01-10
ES3066030T3 (en) 2026-05-11
EP4242637A3 (de) 2023-10-04
EP4242637B1 (de) 2026-02-18
EP4242637A2 (de) 2023-09-13
CN107430064B (zh) 2020-10-20
US20180038845A1 (en) 2018-02-08
DE102015003019A1 (de) 2016-09-08
EP4242637C0 (de) 2026-02-18
CN107430064A (zh) 2017-12-01

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