ES2897731T3 - Composiciones y métodos para reforzar la eficacia de la inmunoterapia celular adoptiva - Google Patents

Composiciones y métodos para reforzar la eficacia de la inmunoterapia celular adoptiva Download PDF

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ES2897731T3
ES2897731T3 ES15795073T ES15795073T ES2897731T3 ES 2897731 T3 ES2897731 T3 ES 2897731T3 ES 15795073 T ES15795073 T ES 15795073T ES 15795073 T ES15795073 T ES 15795073T ES 2897731 T3 ES2897731 T3 ES 2897731T3
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cells
modified
cell
population
cancer
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Susanna Berger
Stanley Riddell
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Fred Hutchinson Cancer Center
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Fred Hutchinson Cancer Center
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Gynecology & Obstetrics (AREA)
ES15795073T 2014-10-27 2015-10-27 Composiciones y métodos para reforzar la eficacia de la inmunoterapia celular adoptiva Active ES2897731T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462069168P 2014-10-27 2014-10-27
PCT/US2015/057652 WO2016069647A1 (en) 2014-10-27 2015-10-27 Compositions and methods for boosting the efficacy of adoptive cellular immunotherapy

Publications (1)

Publication Number Publication Date
ES2897731T3 true ES2897731T3 (es) 2022-03-02

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ES15795073T Active ES2897731T3 (es) 2014-10-27 2015-10-27 Composiciones y métodos para reforzar la eficacia de la inmunoterapia celular adoptiva

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Country Link
US (1) US10828352B2 (enExample)
EP (1) EP3212223B1 (enExample)
JP (1) JP7005346B2 (enExample)
KR (1) KR102357004B1 (enExample)
CN (1) CN107106611B (enExample)
AU (1) AU2015339402B2 (enExample)
BR (2) BR122021000068A8 (enExample)
CA (1) CA2965347C (enExample)
ES (1) ES2897731T3 (enExample)
HK (1) HK1243631A1 (enExample)
MX (1) MX389823B (enExample)
NZ (1) NZ731279A (enExample)
RU (1) RU2716716C2 (enExample)
WO (1) WO2016069647A1 (enExample)

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KR102508166B1 (ko) 2014-04-10 2023-03-13 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 세포 면역요법을 위한 방법 및 조성물
JP6865688B2 (ja) 2015-01-16 2021-04-28 ジュノー セラピューティクス インコーポレイテッド Ｒｏｒ１に特異的な抗体およびキメラ抗原受容体
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CN106199005B (zh) * 2016-07-26 2019-02-01 浙江大学 采用cd137表达量检测淋巴细胞抗大肠癌活性的方法
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JP2020533962A (ja) * 2017-08-11 2020-11-26 フレッド ハッチンソン キャンサー リサーチ センター Ｂｒａｆ特異的ｔｃｒおよびその使用
JP7654240B2 (ja) * 2017-09-19 2025-04-01 マサチューセッツ インスティテュート オブ テクノロジー キメラ抗原受容体ｔ細胞治療のための組成物およびその使用
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