KR102357004B1 - 입양 세포 면역요법의 효능을 강화하기 위한 조성물 및 방법 - Google Patents
입양 세포 면역요법의 효능을 강화하기 위한 조성물 및 방법 Download PDFInfo
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- KR102357004B1 KR102357004B1 KR1020177013868A KR20177013868A KR102357004B1 KR 102357004 B1 KR102357004 B1 KR 102357004B1 KR 1020177013868 A KR1020177013868 A KR 1020177013868A KR 20177013868 A KR20177013868 A KR 20177013868A KR 102357004 B1 KR102357004 B1 KR 102357004B1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Developmental Biology & Embryology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pregnancy & Childbirth (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462069168P | 2014-10-27 | 2014-10-27 | |
| US62/069,168 | 2014-10-27 | ||
| PCT/US2015/057652 WO2016069647A1 (en) | 2014-10-27 | 2015-10-27 | Compositions and methods for boosting the efficacy of adoptive cellular immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20170068600A KR20170068600A (ko) | 2017-06-19 |
| KR102357004B1 true KR102357004B1 (ko) | 2022-01-27 |
Family
ID=54545485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177013868A Active KR102357004B1 (ko) | 2014-10-27 | 2015-10-27 | 입양 세포 면역요법의 효능을 강화하기 위한 조성물 및 방법 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10828352B2 (enExample) |
| EP (1) | EP3212223B1 (enExample) |
| JP (1) | JP7005346B2 (enExample) |
| KR (1) | KR102357004B1 (enExample) |
| CN (1) | CN107106611B (enExample) |
| AU (1) | AU2015339402B2 (enExample) |
| BR (2) | BR112017008710A8 (enExample) |
| CA (1) | CA2965347C (enExample) |
| ES (1) | ES2897731T3 (enExample) |
| HK (1) | HK1243631A1 (enExample) |
| MX (1) | MX389823B (enExample) |
| NZ (1) | NZ731279A (enExample) |
| RU (1) | RU2716716C2 (enExample) |
| WO (1) | WO2016069647A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2636503C2 (ru) | 2011-09-08 | 2017-11-23 | Иеда Рисеч Энд Девелопмент Ко. Лтд. | Т-клетки центральной памяти против третьей стороны, способы их получения и их применение в трансплантации и лечении заболеваний |
| EP3563872A1 (en) | 2012-04-05 | 2019-11-06 | Massachusetts Institute Of Technology | Immunostimulatory compositions and methods of use thereof |
| US10611837B2 (en) | 2014-04-10 | 2020-04-07 | Seattle Children's Hospital | Transgene genetic tags and methods of use |
| AR103442A1 (es) | 2015-01-16 | 2017-05-10 | Juno Therapeutics Inc | Anticuerpos y receptores de antígenos quiméricos específicos de ror1 |
| CN108135938A (zh) | 2015-07-16 | 2018-06-08 | 耶达研究及发展有限公司 | 基因修饰的抗第三方中央型记忆t细胞及其在免疫疗法中的用途 |
| KR20180033537A (ko) | 2015-07-21 | 2018-04-03 | 더 칠드런스 메디칼 센터 코포레이션 | Pd-l1 발현 조혈 줄기 세포 및 용도 |
| US11458167B2 (en) | 2015-08-07 | 2022-10-04 | Seattle Children's Hospital | Bispecific CAR T-cells for solid tumor targeting |
| HK1254836A1 (zh) | 2015-10-30 | 2019-07-26 | Nbe-Therapeutics Ag | 抗-ror1抗体 |
| BR112018014615A2 (pt) | 2016-01-20 | 2018-12-11 | The Scripps Research Institute | composições de anticorpo para ror1 e métodos relacionados |
| MX2018009011A (es) | 2016-02-02 | 2018-11-19 | Hutchinson Fred Cancer Res | Anticuerpos anti receptor 1 transmembrana de tirosina-proteina cinasa (ror1) y usos de los mismos. |
| US11723962B2 (en) | 2016-05-04 | 2023-08-15 | Fred Hutchinson Cancer Center | Cell-based neoantigen vaccines and uses thereof |
| CA3025024A1 (en) * | 2016-05-20 | 2017-11-23 | Eli Lilly And Company | Combination therapy with notch and pd-1 or pd-l1 inhibitors |
| CN106199005B (zh) * | 2016-07-26 | 2019-02-01 | 浙江大学 | 采用cd137表达量检测淋巴细胞抗大肠癌活性的方法 |
| ES2961666T3 (es) | 2016-12-03 | 2024-03-13 | Juno Therapeutics Inc | Métodos para determinar la dosificación de células CAR-T |
| WO2018106732A1 (en) | 2016-12-05 | 2018-06-14 | Juno Therapeutics, Inc. | Production of engineered cells for adoptive cell therapy |
| CN110392736A (zh) * | 2017-01-18 | 2019-10-29 | 耶达研究及发展有限公司 | 遗传修饰的反抑细胞及其在免疫治疗中的用途 |
| CN107267555B (zh) | 2017-05-27 | 2020-03-20 | 上海优卡迪生物医药科技有限公司 | 一种基于octs技术的恶性胶质瘤car-t治疗载体及其构建方法和应用 |
| SG11202000846WA (en) | 2017-08-07 | 2020-02-27 | Nbe Therapeutics Ag | Anthracycline-based antibody drug conjugates having high in vivo tolerability |
| EP3665191A4 (en) * | 2017-08-11 | 2021-05-05 | Fred Hutchinson Cancer Research Center | SPECIFIC BRAF TCRs AND RELATED USES |
| MX2020002901A (es) * | 2017-09-19 | 2020-07-22 | Massachusetts Inst Technology | Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas. |
| US11879137B2 (en) | 2017-09-22 | 2024-01-23 | The Children's Medical Center Corporation | Treatment of type 1 diabetes and autoimmune diseases or disorders |
| MX2020007357A (es) * | 2017-09-26 | 2021-08-11 | Longwood Univ | Reporte de antígeno quimérico específico de pd1 como una inmunoterapia. |
| TWI687227B (zh) * | 2017-10-03 | 2020-03-11 | 生倍科技股份有限公司 | 用於t細胞免疫療法之組合及其用途 |
| JP7517983B2 (ja) * | 2017-11-20 | 2024-07-17 | ユリウス-マクシミリアン-ウニヴェルシテート・ヴュルツブルク | 非常に低レベルのcd19を発現する骨髄腫細胞を除去するcd19cart細胞 |
| KR20200116081A (ko) | 2017-12-01 | 2020-10-08 | 주노 쎄러퓨티크스 인코퍼레이티드 | 유전자 조작된 세포의 투약 및 조절 방법 |
| CN109810995B (zh) * | 2017-12-06 | 2020-10-02 | 阿思科力(苏州)生物科技有限公司 | 编码car的核苷酸序列、表达该car的robo1 car-nk细胞及其制备和应用 |
| CN108148137B (zh) * | 2017-12-29 | 2021-03-23 | 中国人民解放军第四军医大学 | 一种b7h4/1e10单克隆抗体及其应用 |
| BR112021003830A2 (pt) * | 2018-08-28 | 2021-07-20 | Fred Hutchinson Cancer Research Center | métodos e composições para terapia celular t adotiva incorporando sinalização notch induzida |
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| CN107106611B (zh) | 2021-11-23 |
| WO2016069647A1 (en) | 2016-05-06 |
| KR20170068600A (ko) | 2017-06-19 |
| US20170246279A1 (en) | 2017-08-31 |
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