ES2871823T3 - Biomarcadores relacionados con la función renal y métodos para utilizarlos - Google Patents

Biomarcadores relacionados con la función renal y métodos para utilizarlos Download PDF

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Publication number
ES2871823T3
ES2871823T3 ES19176215T ES19176215T ES2871823T3 ES 2871823 T3 ES2871823 T3 ES 2871823T3 ES 19176215 T ES19176215 T ES 19176215T ES 19176215 T ES19176215 T ES 19176215T ES 2871823 T3 ES2871823 T3 ES 2871823T3
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subject
level
ckd
acetylalanine
biomarkers
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ES19176215T
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English (en)
Spanish (es)
Inventor
Regis Perichon
Jeffery Cobb
Meredith Brown
Adam Kennedy
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Metabolon Inc
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Metabolon Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES19176215T 2013-05-14 2014-05-13 Biomarcadores relacionados con la función renal y métodos para utilizarlos Active ES2871823T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361822965P 2013-05-14 2013-05-14

Publications (1)

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ES2871823T3 true ES2871823T3 (es) 2021-11-02

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ES14797070T Active ES2702123T3 (es) 2013-05-14 2014-05-13 Biomarcadores relacionados con la función renal y métodos para utilizarlos
ES19176215T Active ES2871823T3 (es) 2013-05-14 2014-05-13 Biomarcadores relacionados con la función renal y métodos para utilizarlos

Family Applications Before (1)

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Country Status (10)

Country Link
US (2) US10539575B2 (cg-RX-API-DMAC7.html)
EP (3) EP2997366B1 (cg-RX-API-DMAC7.html)
JP (1) JP6595984B2 (cg-RX-API-DMAC7.html)
CN (2) CN110196335A (cg-RX-API-DMAC7.html)
AU (1) AU2014265669B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015028253A2 (cg-RX-API-DMAC7.html)
CA (2) CA3184836A1 (cg-RX-API-DMAC7.html)
ES (2) ES2702123T3 (cg-RX-API-DMAC7.html)
MX (2) MX391220B (cg-RX-API-DMAC7.html)
WO (1) WO2014186311A1 (cg-RX-API-DMAC7.html)

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ES2702123T3 (es) * 2013-05-14 2019-02-27 Metabolon Inc Biomarcadores relacionados con la función renal y métodos para utilizarlos
WO2015057968A2 (en) 2013-10-17 2015-04-23 The General Hospital Corporation Methods of identifying subjects responsive to treatment for an autoimmune disease and compositions for treating the same
HUE056203T2 (hu) * 2015-01-09 2022-01-28 Global Genomics Group Llc Vér alapú biomarkerek atheroszklerotikus koszorúsér betegség diagnosztizálására
US20180003721A1 (en) * 2015-01-15 2018-01-04 Joslin Diabetes Center Metabolite Biomarkers Predictive Of Renal Disease In Diabetic Patients
EP3355914B1 (en) * 2015-09-29 2024-03-06 The General Hospital Corporation A composition comprising bcg for reducing cholesterol.
US20170234874A1 (en) * 2015-10-07 2017-08-17 Clearbridge Biophotonics Pte Ltd. Integrated visual morphology and cell protein expression using resonance-light scattering
US12057228B1 (en) * 2015-12-30 2024-08-06 Cerner Innovation, Inc. Predicting newly incident chronic kidney disease
ES2891088T3 (es) * 2016-07-28 2022-01-26 Metabolon Inc Métodos de diagnóstico, agentes terapéuticos y usos de los mismos
CN110392832A (zh) * 2016-11-25 2019-10-29 内佩西翁有限公司 代谢病症
JP7393206B2 (ja) * 2016-12-19 2023-12-06 メタボロン,インコーポレイテッド 腎機能代謝産物の検出及び定量化のための質量分析アッセイ方法
CN108956790A (zh) * 2017-05-18 2018-12-07 中国人民解放军第二军医大学第二附属医院 一组氨基酸标志物在急性肾损伤诊断试剂盒中的应用
CN107132266A (zh) * 2017-06-21 2017-09-05 佛山科学技术学院 一种基于随机森林的水质分类方法及系统
EP4567822A3 (en) 2017-08-08 2025-09-10 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
CN107326093B (zh) * 2017-09-04 2020-01-21 东南大学 基于Taqman探针的慢性肾脏病相关基因检测荧光定量PCR一步法试剂盒及其应用
EP3688470A1 (en) * 2017-09-28 2020-08-05 Metabolon, Inc. Compounds, reagents, and uses thereof
US20210293829A1 (en) * 2018-01-19 2021-09-23 Mars, Incorporated Biomarkers and classification algorithms for chronic kidney disease in cats
JP7633147B2 (ja) * 2018-07-14 2025-02-19 マース インコーポレーテッド 慢性腎臓病のためのバイオマーカー及びテストモデル
CN113454462A (zh) * 2019-02-20 2021-09-28 株式会社合伙企业 固相反应芯片和使用该固相反应芯片的测定方法
KR20220041883A (ko) * 2019-07-26 2022-04-01 펀다시오 인스티튜트 드’인베스티가시오 바이오메티칼 드 벨리비티게 (아이디벨) 에르고티오네인, s-메틸-에르고티오네인 및 이들의 용도
CN112305089B (zh) * 2019-07-26 2022-04-29 长沙都正生物科技股份有限公司 一种慢性肾病诊断生物标记物及其应用
CN111487338B (zh) * 2020-04-16 2022-06-10 中南大学湘雅二医院 一种与肾功能相关的无创生物标记物及其应用
WO2021232211A1 (zh) * 2020-05-19 2021-11-25 深圳市中医院 诊断肾病的标志物以及诊断方法
CN114910587B (zh) * 2022-05-12 2024-03-19 军科正源(上海)生物医药科技有限公司 一种尿液检测用高效液相-串联质谱分析方法

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Also Published As

Publication number Publication date
JP2016520192A (ja) 2016-07-11
CN105209909A (zh) 2015-12-30
US20160116486A1 (en) 2016-04-28
MX2015015561A (es) 2016-02-05
EP3410115A1 (en) 2018-12-05
EP2997366A1 (en) 2016-03-23
CN110196335A (zh) 2019-09-03
EP2997366A4 (en) 2017-04-12
MX2019005748A (es) 2019-08-12
EP2997366B1 (en) 2018-10-10
CA2911204A1 (en) 2014-11-20
US20200103417A1 (en) 2020-04-02
WO2014186311A1 (en) 2014-11-20
CN105209909B (zh) 2019-06-07
CA3184836A1 (en) 2014-11-20
MX365061B (es) 2019-05-22
BR112015028253A2 (pt) 2017-07-25
JP6595984B2 (ja) 2019-10-23
AU2014265669A1 (en) 2015-12-24
AU2014265669B2 (en) 2020-05-14
EP3546940B1 (en) 2021-02-17
US10539575B2 (en) 2020-01-21
HK1218331A1 (zh) 2017-02-10
EP3546940A1 (en) 2019-10-02
MX391220B (es) 2025-03-21
ES2702123T3 (es) 2019-02-27
HK1222905A1 (en) 2017-07-14
CA2911204C (en) 2023-03-28

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