ES2854352T3 - Sistema de bioensayo y método para detectar analitos en fluidos corporales - Google Patents

Sistema de bioensayo y método para detectar analitos en fluidos corporales Download PDF

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Publication number
ES2854352T3
ES2854352T3 ES15717699T ES15717699T ES2854352T3 ES 2854352 T3 ES2854352 T3 ES 2854352T3 ES 15717699 T ES15717699 T ES 15717699T ES 15717699 T ES15717699 T ES 15717699T ES 2854352 T3 ES2854352 T3 ES 2854352T3
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ES
Spain
Prior art keywords
antibody
grating
resonance
target analyte
epitope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15717699T
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English (en)
Spanish (es)
Inventor
Josef Kerimo
Hansong Zeng
Ron Scharlack
Gert Blankenstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Werfen North America
Original Assignee
Instrumentation Laboratory Co
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Publication date
Application filed by Instrumentation Laboratory Co filed Critical Instrumentation Laboratory Co
Application granted granted Critical
Publication of ES2854352T3 publication Critical patent/ES2854352T3/es
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
ES15717699T 2014-03-24 2015-03-20 Sistema de bioensayo y método para detectar analitos en fluidos corporales Active ES2854352T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461969371P 2014-03-24 2014-03-24
PCT/US2015/021651 WO2015148290A1 (en) 2014-03-24 2015-03-20 Bioassay system and method for detecting analytes in body fluids

Publications (1)

Publication Number Publication Date
ES2854352T3 true ES2854352T3 (es) 2021-09-21

Family

ID=52991948

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15717699T Active ES2854352T3 (es) 2014-03-24 2015-03-20 Sistema de bioensayo y método para detectar analitos en fluidos corporales

Country Status (8)

Country Link
US (1) US20150268237A1 (https=)
EP (1) EP3123172B1 (https=)
JP (1) JP6606509B2 (https=)
CN (1) CN106461559B (https=)
AU (1) AU2015236470B2 (https=)
CA (1) CA2943254C (https=)
ES (1) ES2854352T3 (https=)
WO (1) WO2015148290A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11016087B2 (en) * 2016-02-09 2021-05-25 Sekisui Chemical Co., Ltd. Implement for inspection, inspecting device and inspecting method
JP6633978B2 (ja) * 2016-06-17 2020-01-22 積水化学工業株式会社 検査キット及び検査方法
US10877192B2 (en) 2017-04-18 2020-12-29 Saudi Arabian Oil Company Method of fabricating smart photonic structures for material monitoring
US10401155B2 (en) 2017-05-12 2019-09-03 Saudi Arabian Oil Company Apparatus and method for smart material analysis
CN107356570B (zh) * 2017-06-08 2020-10-27 大连海事大学 一种固态上转换荧光探针及其制备方法与应用
ES3030268T3 (en) * 2017-06-08 2025-06-27 Lumito Ab A method of analysing a sample for at least one analyte
US10746534B2 (en) 2017-07-03 2020-08-18 Saudi Arabian Oil Company Smart coating device for storage tank monitoring and calibration
US20200132583A1 (en) * 2017-07-11 2020-04-30 Aviana Molecular Technologies, Llc Signal amplification in biosensor device
CN108163802B (zh) * 2017-12-06 2020-02-07 北京纳百生物科技有限公司 一种抗原检测材料及其制备方法和应用
EP3832292B1 (en) * 2018-07-31 2023-08-30 Sekisui Chemical Co., Ltd. Inspecting method, inspecting instrument, and inspecting device
CN108957839B (zh) * 2018-08-09 2022-09-30 京东方科技集团股份有限公司 显示装置、显示面板、彩膜基板及彩膜
CN109470652A (zh) * 2018-10-24 2019-03-15 北京邮电大学 基于Fano谐振的椭圆空气孔部分刻蚀型光子晶体传感器
US11391730B2 (en) * 2019-12-31 2022-07-19 Robert Bosch Gmbh Sensor refresh systems
CN120712049A (zh) 2022-12-15 2025-09-26 阿达普提克斯生物科学公司 用于分析物检测的系统和方法
WO2025100392A1 (ja) * 2023-11-06 2025-05-15 公立大学法人大阪 光学センサ、被検出物質の検出システムおよび光学センサの製造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
EP0723146B1 (en) * 1992-09-14 2004-05-06 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
JP2001116699A (ja) * 1999-10-21 2001-04-27 Ngk Insulators Ltd 遺伝子診断方法
US6951715B2 (en) * 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US6560020B1 (en) * 2001-01-16 2003-05-06 Holotek, Llc Surface-relief diffraction grating
US7008559B2 (en) * 2001-06-06 2006-03-07 Nomadics, Inc. Manganese doped upconversion luminescence nanoparticles
EP1616169B1 (en) * 2003-03-27 2009-06-24 Corning Incorporated Label-free evanescent-field detection of biological and chemical agents
JP2007240361A (ja) * 2006-03-09 2007-09-20 Sekisui Chem Co Ltd 局在プラズモン増強センサ
EP1912067A1 (en) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Method for quantification of a target compound obtained from a biological sample upon chips
ES2490613T3 (es) * 2008-12-22 2014-09-04 F. Hoffmann-La Roche Ag ARMET como marcador de cáncer
CN102375060B (zh) * 2010-08-19 2014-12-31 中国人民解放军军事医学科学院微生物流行病研究所 一种基于上转换发光十通道免疫层析的食源性致病菌检测试纸盘
SG11201403234VA (en) * 2011-12-19 2014-07-30 Univ Nanyang Tech Synthesis of upconversion nanocomposites for photodynamic therapy
JP5975480B2 (ja) * 2012-01-31 2016-08-23 国立研究開発法人産業技術総合研究所 バイオチップ、バイオアッセイ用キット、及びバイオアッセイ方法
CN104520239A (zh) * 2012-07-12 2015-04-15 新加坡国立大学 上转换荧光纳米颗粒

Also Published As

Publication number Publication date
AU2015236470B2 (en) 2019-03-07
AU2015236470A1 (en) 2016-10-06
CN106461559A (zh) 2017-02-22
JP2017508975A (ja) 2017-03-30
US20150268237A1 (en) 2015-09-24
EP3123172A1 (en) 2017-02-01
CN106461559B (zh) 2020-07-03
CA2943254C (en) 2021-05-04
EP3123172B1 (en) 2021-01-13
CA2943254A1 (en) 2015-10-01
JP6606509B2 (ja) 2019-11-13
WO2015148290A1 (en) 2015-10-01

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