ES2834402T3 - Terapia génica con RPGR para retinitis pigmentosa - Google Patents
Terapia génica con RPGR para retinitis pigmentosa Download PDFInfo
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- ES2834402T3 ES2834402T3 ES15825383T ES15825383T ES2834402T3 ES 2834402 T3 ES2834402 T3 ES 2834402T3 ES 15825383 T ES15825383 T ES 15825383T ES 15825383 T ES15825383 T ES 15825383T ES 2834402 T3 ES2834402 T3 ES 2834402T3
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
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- C—CHEMISTRY; METALLURGY
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028638P | 2014-07-24 | 2014-07-24 | |
| PCT/US2015/040866 WO2016014353A1 (en) | 2014-07-24 | 2015-07-17 | Rpgr gene therapy for retinitis pigmentosa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2834402T3 true ES2834402T3 (es) | 2021-06-17 |
Family
ID=55163577
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15825383T Active ES2834402T3 (es) | 2014-07-24 | 2015-07-17 | Terapia génica con RPGR para retinitis pigmentosa |
| ES20199208T Active ES2987090T3 (es) | 2014-07-24 | 2015-07-17 | Terapia génica con RPGR para retinitis pigmentosa |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES20199208T Active ES2987090T3 (es) | 2014-07-24 | 2015-07-17 | Terapia génica con RPGR para retinitis pigmentosa |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10314924B2 (enExample) |
| EP (2) | EP3821912B1 (enExample) |
| JP (3) | JP6654760B2 (enExample) |
| CN (1) | CN107206105A (enExample) |
| CA (1) | CA2991750C (enExample) |
| CY (1) | CY1123793T1 (enExample) |
| DK (2) | DK3191139T3 (enExample) |
| ES (2) | ES2834402T3 (enExample) |
| FI (1) | FI3821912T3 (enExample) |
| HR (2) | HRP20241154T1 (enExample) |
| HU (2) | HUE068183T2 (enExample) |
| LT (2) | LT3191139T (enExample) |
| PL (2) | PL3191139T3 (enExample) |
| PT (2) | PT3821912T (enExample) |
| RS (2) | RS65909B1 (enExample) |
| SI (2) | SI3191139T1 (enExample) |
| SM (2) | SMT202400309T1 (enExample) |
| WO (1) | WO2016014353A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016014353A1 (en) * | 2014-07-24 | 2016-01-28 | Massachusetts Eye & Ear Infirmary | Rpgr gene therapy for retinitis pigmentosa |
| US20190054117A1 (en) * | 2014-12-19 | 2019-02-21 | Novartis Ag | Dimerization switches and uses thereof |
| AU2016228751B2 (en) | 2015-03-11 | 2022-01-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rp2 vectors for treating x-linked retinitis pigmentosa |
| GB201516066D0 (en) | 2015-09-10 | 2015-10-28 | Young & Co Llp D | Treatment of retinitis pigmentosa |
| GB201704192D0 (en) | 2017-03-16 | 2017-05-03 | Nightstarx Ltd | Treatment of Retinitis Pigmentosa |
| KR102763312B1 (ko) * | 2017-10-20 | 2025-02-07 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 치료적으로 유효한 양의 재조합 aav9- 유도 벡터의 망막하 전달을 포함하는 대상체의 원추 광수용체 내 관심의 폴리뉴클레오티드를 발현하는 방법 |
| MY204271A (en) | 2017-11-15 | 2024-08-20 | Ucl Business Ltd | Viral vectors comprising rdh12 coding regions and methods of treating retinal dystrophies |
| CA3174781A1 (en) | 2020-03-11 | 2021-09-16 | Massachusetts Eye And Ear Infirmary | Gene therapy for nmnat1-associated retinal degeneration |
| CN120350069A (zh) * | 2024-01-12 | 2025-07-22 | 北京中因科技有限公司 | 视网膜色素变性动物模型及其构建方法和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| AU6131086A (en) | 1985-07-05 | 1987-01-30 | Whitehead Institute For Biomedical Research | Epithelial cells expressing foreign genetic material |
| DE3852823T2 (de) | 1987-09-11 | 1995-05-24 | Hughes Howard Med Inst | Transduktionsveränderte fibroblasten und ihre anwendung. |
| JP2914692B2 (ja) | 1987-12-11 | 1999-07-05 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 内皮細胞の遺伝子修飾 |
| EP0400047B1 (en) | 1988-02-05 | 1997-04-23 | Whitehead Institute For Biomedical Research | Modified hepatocytes and uses therefor |
| EP0556345B2 (en) | 1990-10-31 | 2005-10-12 | Cell Genesys, Inc. | Retroviral vectors useful for gene therapy |
| US5767079A (en) * | 1992-07-08 | 1998-06-16 | Celtrix Pharmaceuticals, Inc. | Method of treating ophthalmic disorders using TGF -β |
| AU2044901A (en) * | 1999-11-24 | 2001-06-04 | Cornell Research Foundation Inc. | Inherited retinal diseases at the canine rp3 locus: linkage, marker- and mutation-based tests |
| GB0008801D0 (en) * | 2000-04-10 | 2000-05-31 | Medical Res Council | Sequences |
| CN102925445A (zh) * | 2011-08-08 | 2013-02-13 | 刘军 | 一种获得rpgr 基因新的转录剪切形式的方法 |
| EP2872183B1 (en) * | 2012-07-11 | 2018-09-26 | The Trustees Of The University Of Pennsylvania | Aav-mediated gene therapy for rpgr x-linked retinal degeneration |
| GB201412011D0 (en) * | 2014-07-04 | 2014-08-20 | Ucl Business Plc | Treatments |
| WO2016014353A1 (en) * | 2014-07-24 | 2016-01-28 | Massachusetts Eye & Ear Infirmary | Rpgr gene therapy for retinitis pigmentosa |
-
2015
- 2015-07-17 WO PCT/US2015/040866 patent/WO2016014353A1/en not_active Ceased
- 2015-07-17 CA CA2991750A patent/CA2991750C/en active Active
- 2015-07-17 ES ES15825383T patent/ES2834402T3/es active Active
- 2015-07-17 CN CN201580051512.3A patent/CN107206105A/zh active Pending
- 2015-07-17 PL PL15825383T patent/PL3191139T3/pl unknown
- 2015-07-17 FI FIEP20199208.8T patent/FI3821912T3/fi active
- 2015-07-17 LT LTEP15825383.1T patent/LT3191139T/lt unknown
- 2015-07-17 PT PT201992088T patent/PT3821912T/pt unknown
- 2015-07-17 PL PL20199208.8T patent/PL3821912T3/pl unknown
- 2015-07-17 DK DK15825383.1T patent/DK3191139T3/da active
- 2015-07-17 RS RS20240901A patent/RS65909B1/sr unknown
- 2015-07-17 EP EP20199208.8A patent/EP3821912B1/en active Active
- 2015-07-17 HU HUE20199208A patent/HUE068183T2/hu unknown
- 2015-07-17 RS RS20201416A patent/RS61307B1/sr unknown
- 2015-07-17 ES ES20199208T patent/ES2987090T3/es active Active
- 2015-07-17 SM SM20240309T patent/SMT202400309T1/it unknown
- 2015-07-17 LT LTEP20199208.8T patent/LT3821912T/lt unknown
- 2015-07-17 HR HRP20241154TT patent/HRP20241154T1/hr unknown
- 2015-07-17 SI SI201531413T patent/SI3191139T1/sl unknown
- 2015-07-17 HR HRP20202023TT patent/HRP20202023T1/hr unknown
- 2015-07-17 SM SM20200715T patent/SMT202000715T1/it unknown
- 2015-07-17 HU HUE15825383A patent/HUE052781T2/hu unknown
- 2015-07-17 US US15/328,617 patent/US10314924B2/en active Active
- 2015-07-17 PT PT158253831T patent/PT3191139T/pt unknown
- 2015-07-17 DK DK20199208.8T patent/DK3821912T3/da active
- 2015-07-17 JP JP2017525514A patent/JP6654760B2/ja active Active
- 2015-07-17 SI SI201532022T patent/SI3821912T1/sl unknown
- 2015-07-17 EP EP15825383.1A patent/EP3191139B1/en active Active
-
2019
- 2019-06-10 US US16/436,521 patent/US11045558B2/en active Active
- 2019-12-26 JP JP2019235539A patent/JP6966532B2/ja active Active
-
2021
- 2021-01-05 CY CY20211100002T patent/CY1123793T1/el unknown
- 2021-10-21 JP JP2021172128A patent/JP7198329B2/ja active Active
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