ES2774198T3 - Derivados hidroxamatos de triterpenoides - Google Patents
Derivados hidroxamatos de triterpenoides Download PDFInfo
- Publication number
- ES2774198T3 ES2774198T3 ES17790966T ES17790966T ES2774198T3 ES 2774198 T3 ES2774198 T3 ES 2774198T3 ES 17790966 T ES17790966 T ES 17790966T ES 17790966 T ES17790966 T ES 17790966T ES 2774198 T3 ES2774198 T3 ES 2774198T3
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- Prior art keywords
- hydroxy
- carbon
- amide
- present
- olean
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- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
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| EP16193684 | 2016-10-13 | ||
| PCT/EP2017/075042 WO2018069086A1 (en) | 2016-10-13 | 2017-10-03 | Hydroxamate triterpenoid derivatives |
Publications (1)
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| ES2774198T3 true ES2774198T3 (es) | 2020-07-17 |
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| WO2020157494A1 (en) * | 2019-01-30 | 2020-08-06 | Rothamsted Research Ltd | Cylodimer of dehydrosalicortin and derivatives thereof isolated from plant of the genus salix for use in cancer therapy |
| CN114805469A (zh) * | 2021-01-27 | 2022-07-29 | 中国科学院上海药物研究所 | 含吡唑的白桦脂酸类衍生物，其制备方法及用途 |
| CN117567544A (zh) * | 2021-04-27 | 2024-02-20 | 中国医学科学院药物研究所 | 一类具有α,β-不饱和酮结构五环三萜类化合物在预防和治疗神经退行性疾病中的用途 |
| WO2024145502A1 (en) * | 2022-12-29 | 2024-07-04 | The Board Of Regents Of The University Of Texas System | Synthetic triterpenoids and compositions thereof in weight management, skeletal muscle function, and appetite suppression |
| CN119504913B (zh) * | 2024-11-18 | 2025-09-26 | 南京中医药大学 | 一类五环三萜衍生物及其医药用途 |
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| KR100821649B1 (ko) * | 2006-01-24 | 2008-04-11 | 서울시립대학교 산학협력단 | 클리오퀴놀을 유효성분으로 포함하는 ＨＩＦ-1α 활성제 |
| CN101367861A (zh) * | 2007-08-15 | 2009-02-18 | 中国药科大学 | 2-羟基-3-脱氧五环三萜类化合物及其衍生物、其制备方法及用途 |
| PL2252283T3 (pl) * | 2008-01-11 | 2019-09-30 | Reata Pharmaceuticals, Inc. | Syntetyczne triterpenoidy i sposoby zastosowania w leczeniu choroby |
| WO2009146216A2 (en) * | 2008-04-18 | 2009-12-03 | Reata Pharmaceuticals. Inc. | Antioxidant inflammation modulators: novel derivatives of oleanolic acid |
| US20100144688A1 (en) * | 2008-12-10 | 2010-06-10 | Advanced Life Sciences, Inc. | 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids |
| KR101811462B1 (ko) * | 2010-01-11 | 2018-01-25 | 피닉스 바이오테크놀러지 인코포레이티드. | 협죽도 추출물을 포함하는 신경질환 치료용 조성물 |
| CN102180939B (zh) | 2011-03-30 | 2013-02-20 | 沈阳化工大学 | 一种抗肿瘤活性的熊果酸化学修饰物及其制备方法 |
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| CN102499925B (zh) * | 2011-10-21 | 2015-11-11 | 上海中医药大学 | 一种中性粒细胞弹性蛋白酶抑制剂 |
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