KR102038930B1 - 하이드록시메이트 트리테르페노이드 유도체 - Google Patents

하이드록시메이트 트리테르페노이드 유도체 Download PDF

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KR102038930B1
KR102038930B1 KR1020187028923A KR20187028923A KR102038930B1 KR 102038930 B1 KR102038930 B1 KR 102038930B1 KR 1020187028923 A KR1020187028923 A KR 1020187028923A KR 20187028923 A KR20187028923 A KR 20187028923A KR 102038930 B1 KR102038930 B1 KR 102038930B1
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hydroxy
amide
activation
disease
hif
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KR20180117700A (ko
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블랑코 에듀왈도 뮤노즈
알베르토 미나시
카벨로 디 알바 마리아 루즈 벨리도
지오바니 아펜디노
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비바셀 바이오테크놀로지 에스파냐, 에스. 엘
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020187028923A 2016-10-13 2017-10-03 하이드록시메이트 트리테르페노이드 유도체 Expired - Fee Related KR102038930B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16193684.4 2016-10-13
EP16193684 2016-10-13
PCT/EP2017/075042 WO2018069086A1 (en) 2016-10-13 2017-10-03 Hydroxamate triterpenoid derivatives

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KR20180117700A KR20180117700A (ko) 2018-10-29
KR102038930B1 true KR102038930B1 (ko) 2019-11-05

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US (1) US10766855B2 (https=)
EP (1) EP3365351B1 (https=)
JP (1) JP6598224B2 (https=)
KR (1) KR102038930B1 (https=)
CN (1) CN108368150B (https=)
AU (1) AU2017341257B2 (https=)
BR (1) BR112018068996A2 (https=)
CA (1) CA3020387C (https=)
ES (1) ES2774198T3 (https=)
HK (1) HK1254200A1 (https=)
IL (1) IL259391B (https=)
MX (2) MX364919B (https=)
RU (1) RU2018136782A (https=)
WO (1) WO2018069086A1 (https=)

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WO2020157494A1 (en) * 2019-01-30 2020-08-06 Rothamsted Research Ltd Cylodimer of dehydrosalicortin and derivatives thereof isolated from plant of the genus salix for use in cancer therapy
CN114805469A (zh) * 2021-01-27 2022-07-29 中国科学院上海药物研究所 含吡唑的白桦脂酸类衍生物，其制备方法及用途
CN117567544A (zh) * 2021-04-27 2024-02-20 中国医学科学院药物研究所 一类具有α,β-不饱和酮结构五环三萜类化合物在预防和治疗神经退行性疾病中的用途
WO2024145502A1 (en) * 2022-12-29 2024-07-04 The Board Of Regents Of The University Of Texas System Synthetic triterpenoids and compositions thereof in weight management, skeletal muscle function, and appetite suppression
CN119504913B (zh) * 2024-11-18 2025-09-26 南京中医药大学 一类五环三萜衍生物及其医药用途

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JP2002322068A (ja) * 2001-02-26 2002-11-08 Japan Science & Technology Corp 血管再生促進剤
KR100821649B1 (ko) * 2006-01-24 2008-04-11 서울시립대학교 산학협력단 클리오퀴놀을 유효성분으로 포함하는 ＨＩＦ-1α 활성제
CN101367861A (zh) * 2007-08-15 2009-02-18 中国药科大学 2-羟基-3-脱氧五环三萜类化合物及其衍生物、其制备方法及用途
PL2252283T3 (pl) * 2008-01-11 2019-09-30 Reata Pharmaceuticals, Inc. Syntetyczne triterpenoidy i sposoby zastosowania w leczeniu choroby
WO2009146216A2 (en) * 2008-04-18 2009-12-03 Reata Pharmaceuticals. Inc. Antioxidant inflammation modulators: novel derivatives of oleanolic acid
US20100144688A1 (en) * 2008-12-10 2010-06-10 Advanced Life Sciences, Inc. 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids
KR101811462B1 (ko) * 2010-01-11 2018-01-25 피닉스 바이오테크놀러지 인코포레이티드. 협죽도 추출물을 포함하는 신경질환 치료용 조성물
CN102180939B (zh) 2011-03-30 2013-02-20 沈阳化工大学 一种抗肿瘤活性的熊果酸化学修饰物及其制备方法
US8324264B1 (en) * 2011-07-22 2012-12-04 Sequoia Sciences, Inc. Inhibitors of bacterial biofilms and related methods
CN102499925B (zh) * 2011-10-21 2015-11-11 上海中医药大学 一种中性粒细胞弹性蛋白酶抑制剂

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European Journal of Medicinal Chemistry. Vol. 106, pp. 194-210 (2015.11.05. 온라인 공개) 1부.*
Evidence-Based Complementary and Alternative Medicine. Vol. 2014, Article ID 573745, pp. 1-10 (2014)
Journal of Medicinal Chemistry. Vol. 53, No. 1, pp. 178-190 (2010)

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AU2017341257A1 (en) 2018-11-01
AU2017341257B2 (en) 2019-08-08
IL259391A (en) 2018-07-31
MX2019005448A (es) 2019-07-04
CN108368150A (zh) 2018-08-03
RU2018136782A (ru) 2020-04-20
US10766855B2 (en) 2020-09-08
WO2018069086A1 (en) 2018-04-19
MX2018006429A (es) 2018-09-27
CA3020387C (en) 2020-07-28
IL259391B (en) 2019-10-31
RU2018136782A3 (https=) 2020-04-20
BR112018068996A2 (pt) 2019-01-22
KR20180117700A (ko) 2018-10-29
ES2774198T3 (es) 2020-07-17
EP3365351B1 (en) 2019-12-04
EP3365351A1 (en) 2018-08-29
CN108368150B (zh) 2022-02-25
US20190367447A1 (en) 2019-12-05
CA3020387A1 (en) 2018-04-19
JP6598224B2 (ja) 2019-10-30
MX364919B (es) 2019-05-13
JP2019519464A (ja) 2019-07-11
HK1254200A1 (zh) 2019-07-12

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