IL259391A - Hydroxamate triterpenoid derivatives - Google Patents
Hydroxamate triterpenoid derivativesInfo
- Publication number
- IL259391A IL259391A IL259391A IL25939118A IL259391A IL 259391 A IL259391 A IL 259391A IL 259391 A IL259391 A IL 259391A IL 25939118 A IL25939118 A IL 25939118A IL 259391 A IL259391 A IL 259391A
- Authority
- IL
- Israel
- Prior art keywords
- hydroxamate
- triterpenoid derivatives
- triterpenoid
- derivatives
- hydroxamate triterpenoid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/08—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16193684 | 2016-10-13 | ||
PCT/EP2017/075042 WO2018069086A1 (en) | 2016-10-13 | 2017-10-03 | Hydroxamate triterpenoid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IL259391A true IL259391A (en) | 2018-07-31 |
IL259391B IL259391B (en) | 2019-10-31 |
Family
ID=57136723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL25939118A IL259391B (en) | 2016-10-13 | 2018-05-15 | Hydroxamate triterpenoid derivatives |
Country Status (14)
Country | Link |
---|---|
US (1) | US10766855B2 (en) |
EP (1) | EP3365351B1 (en) |
JP (1) | JP6598224B2 (en) |
KR (1) | KR102038930B1 (en) |
CN (1) | CN108368150B (en) |
AU (1) | AU2017341257B2 (en) |
BR (1) | BR112018068996A2 (en) |
CA (1) | CA3020387C (en) |
ES (1) | ES2774198T3 (en) |
HK (1) | HK1254200A1 (en) |
IL (1) | IL259391B (en) |
MX (2) | MX364919B (en) |
RU (1) | RU2018136782A (en) |
WO (1) | WO2018069086A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3917940A1 (en) * | 2019-01-30 | 2021-12-08 | Rothamsted Research Ltd | Cylodimer of dehydrosalicortin and derivatives thereof isolated from plant of the genus salix for use in cancer therapy |
CN114805469A (en) * | 2021-01-27 | 2022-07-29 | 中国科学院上海药物研究所 | Betulinic acid derivative containing pyrazole, preparation method and application thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101367861A (en) * | 2007-08-15 | 2009-02-18 | 中国药科大学 | 2-hydroxyl-3-deoxidized pentacyclic triterpenoid and derivant, preparation method and uses thereof |
WO2009089545A1 (en) * | 2008-01-11 | 2009-07-16 | Reata Pharmaceuticals, Inc. | Synthetic triterpenoids and methods of use in the treatment of disease |
WO2009146216A2 (en) | 2008-04-18 | 2009-12-03 | Reata Pharmaceuticals. Inc. | Antioxidant inflammation modulators: novel derivatives of oleanolic acid |
CN102180939B (en) | 2011-03-30 | 2013-02-20 | 沈阳化工大学 | Ursolic acid chemical modifier with antitumor activity and preparation method thereof |
US8324264B1 (en) * | 2011-07-22 | 2012-12-04 | Sequoia Sciences, Inc. | Inhibitors of bacterial biofilms and related methods |
CN102499925B (en) * | 2011-10-21 | 2015-11-11 | 上海中医药大学 | A kind of neutrophil elastase inhibitor |
-
2017
- 2017-10-03 AU AU2017341257A patent/AU2017341257B2/en active Active
- 2017-10-03 CN CN201780004882.0A patent/CN108368150B/en active Active
- 2017-10-03 CA CA3020387A patent/CA3020387C/en active Active
- 2017-10-03 BR BR112018068996A patent/BR112018068996A2/en not_active Application Discontinuation
- 2017-10-03 KR KR1020187028923A patent/KR102038930B1/en active IP Right Grant
- 2017-10-03 MX MX2018006429A patent/MX364919B/en active IP Right Grant
- 2017-10-03 US US16/099,800 patent/US10766855B2/en active Active
- 2017-10-03 RU RU2018136782A patent/RU2018136782A/en not_active Application Discontinuation
- 2017-10-03 WO PCT/EP2017/075042 patent/WO2018069086A1/en active Application Filing
- 2017-10-03 ES ES17790966T patent/ES2774198T3/en active Active
- 2017-10-03 JP JP2018524188A patent/JP6598224B2/en active Active
- 2017-10-03 EP EP17790966.0A patent/EP3365351B1/en active Active
-
2018
- 2018-05-15 IL IL25939118A patent/IL259391B/en active IP Right Grant
- 2018-05-24 MX MX2019005448A patent/MX2019005448A/en unknown
- 2018-10-18 HK HK18113340.0A patent/HK1254200A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA3020387A1 (en) | 2018-04-19 |
MX364919B (en) | 2019-05-13 |
AU2017341257A1 (en) | 2018-11-01 |
HK1254200A1 (en) | 2019-07-12 |
MX2018006429A (en) | 2018-09-27 |
JP2019519464A (en) | 2019-07-11 |
WO2018069086A1 (en) | 2018-04-19 |
ES2774198T3 (en) | 2020-07-17 |
US10766855B2 (en) | 2020-09-08 |
AU2017341257B2 (en) | 2019-08-08 |
RU2018136782A3 (en) | 2020-04-20 |
IL259391B (en) | 2019-10-31 |
KR102038930B1 (en) | 2019-11-05 |
CA3020387C (en) | 2020-07-28 |
RU2018136782A (en) | 2020-04-20 |
KR20180117700A (en) | 2018-10-29 |
CN108368150A (en) | 2018-08-03 |
EP3365351A1 (en) | 2018-08-29 |
CN108368150B (en) | 2022-02-25 |
US20190367447A1 (en) | 2019-12-05 |
JP6598224B2 (en) | 2019-10-30 |
EP3365351B1 (en) | 2019-12-04 |
MX2019005448A (en) | 2019-07-04 |
BR112018068996A2 (en) | 2019-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed |