ES2758759T3 - Composiciones y métodos para potenciar las respuestas inmunitarias a eimeria o limitar la infección por eimeria - Google Patents
Composiciones y métodos para potenciar las respuestas inmunitarias a eimeria o limitar la infección por eimeria Download PDFInfo
- Publication number
- ES2758759T3 ES2758759T3 ES14751914T ES14751914T ES2758759T3 ES 2758759 T3 ES2758759 T3 ES 2758759T3 ES 14751914 T ES14751914 T ES 14751914T ES 14751914 T ES14751914 T ES 14751914T ES 2758759 T3 ES2758759 T3 ES 2758759T3
- Authority
- ES
- Spain
- Prior art keywords
- seq
- polypeptide
- vaccine vector
- vaccine
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/012—Coccidia antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361764681P | 2013-02-14 | 2013-02-14 | |
| PCT/US2014/016359 WO2014127185A1 (en) | 2013-02-14 | 2014-02-14 | Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2758759T3 true ES2758759T3 (es) | 2020-05-06 |
Family
ID=51354559
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14751914T Active ES2758759T3 (es) | 2013-02-14 | 2014-02-14 | Composiciones y métodos para potenciar las respuestas inmunitarias a eimeria o limitar la infección por eimeria |
| ES19194676T Active ES2968398T3 (es) | 2013-02-14 | 2014-02-14 | Composiciones y métodos para potenciar las respuestas inmunitarias a Eimeria o limitar la infección por Eimeria |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19194676T Active ES2968398T3 (es) | 2013-02-14 | 2014-02-14 | Composiciones y métodos para potenciar las respuestas inmunitarias a Eimeria o limitar la infección por Eimeria |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US9603915B2 (enExample) |
| EP (2) | EP3610887B8 (enExample) |
| JP (2) | JP6532407B2 (enExample) |
| KR (1) | KR102228324B1 (enExample) |
| CN (2) | CN105142665A (enExample) |
| AR (1) | AR094791A1 (enExample) |
| AU (1) | AU2014216246B2 (enExample) |
| BR (1) | BR112015019283B1 (enExample) |
| CA (1) | CA2900644C (enExample) |
| CL (1) | CL2015002273A1 (enExample) |
| DK (1) | DK2956165T3 (enExample) |
| EA (1) | EA030929B1 (enExample) |
| ES (2) | ES2758759T3 (enExample) |
| HU (1) | HUE047484T2 (enExample) |
| MX (1) | MX2015010555A (enExample) |
| MY (2) | MY200497A (enExample) |
| NZ (1) | NZ711019A (enExample) |
| PH (1) | PH12015501784A1 (enExample) |
| PL (1) | PL2956165T3 (enExample) |
| PT (1) | PT2956165T (enExample) |
| SG (2) | SG10202109925TA (enExample) |
| WO (1) | WO2014127185A1 (enExample) |
| ZA (1) | ZA201505638B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009059298A2 (en) * | 2007-11-01 | 2009-05-07 | Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancinc immune responses to eimeria |
| HUE047484T2 (hu) | 2013-02-14 | 2020-04-28 | Univ Arkansas | Készítmények és eljárások eimeria elleni immunválasz fokozására vagy eimeria-fertõzés korlátozására |
| US10376571B2 (en) | 2013-03-15 | 2019-08-13 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancing immune responses to enteric pathogens |
| CN104940924B (zh) * | 2015-05-29 | 2018-01-16 | 中国农业大学 | 一种球虫佐剂及其应用 |
| KR20190015712A (ko) | 2016-05-03 | 2019-02-14 | 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 | 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법 |
| CN106047914A (zh) * | 2016-05-10 | 2016-10-26 | 吉林大学 | 一种用于预防猪弓形虫病的重组卡介苗及制备方法 |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| WO2018226887A1 (en) | 2017-06-07 | 2018-12-13 | Spark Therapeutics, Inc. | ENHANCING AGENTS FOR IMPROVED CELL TRANSFECTION AND/OR rAAV VECTOR PRODUCTION |
| US12618074B2 (en) | 2019-04-11 | 2026-05-05 | The Board Of Trustees Of The University Of Arkansas | CD40 specific DNA aptamers as vaccine adjuvants |
| US12605239B2 (en) | 2020-07-29 | 2026-04-21 | North Carolina State University | Enhancement of hydration and improvement in gut health through cloacal delivery of products |
| US11497801B2 (en) * | 2021-02-19 | 2022-11-15 | Sherryll Layton | Compositions and methods of enhancing immune responses |
| CN115227810A (zh) * | 2022-04-18 | 2022-10-25 | 福建农林大学 | 一种鸡抗巨型艾美耳球虫口服重组芽孢疫苗及其制备方法 |
Family Cites Families (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK55593A3 (en) | 1991-03-05 | 1993-10-06 | Wellcome Found | Expresion of recombinant proteins in attenuated bacteria |
| US7405270B2 (en) | 1991-10-25 | 2008-07-29 | Immunex Corporation | CD40-Ligand lacking native-pattern glycosylation |
| US5981724A (en) | 1991-10-25 | 1999-11-09 | Immunex Corporation | DNA encoding CD40 ligand, a cytokine that binds CD40 |
| US5962406A (en) | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
| DK0897983T3 (da) | 1991-10-25 | 2003-08-11 | Immunex Corp | Antistoffer mod CD40-L |
| US5716805A (en) | 1991-10-25 | 1998-02-10 | Immunex Corporation | Methods of preparing soluble, oligomeric proteins |
| US5961974A (en) | 1991-10-25 | 1999-10-05 | Immunex Corporation | Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same |
| EP0659086B1 (en) | 1992-09-04 | 1998-11-11 | The University of Saskatchewan | Novel bacterial vaccines using vaccine strains of pathogenic bacteria |
| US5540926A (en) | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
| JP4242447B2 (ja) | 1993-01-22 | 2009-03-25 | イミュネックス・コーポレーション | Cd40リガンド遺伝子の突然変異の検出および治療 |
| AU1059095A (en) | 1993-11-24 | 1995-06-13 | Australian National University, The | Treatment of viral disease with cd40l peptide |
| ATE309267T1 (de) | 1994-04-28 | 2005-11-15 | Boehringer Ingelheim Pharma | Methode zur proliferation und differenzierung von b-zellen und verwendungen dafür |
| PT812206E (pt) | 1995-03-01 | 2002-11-29 | Immunex Corp | Proteina de ligacao a cd40 para estimulacao de uma resposta imunitaria |
| NZ311335A (en) | 1995-06-07 | 1998-05-27 | Immunex Corp | Cd40l muteins and their use as ligands |
| US6479258B1 (en) | 1995-12-07 | 2002-11-12 | Diversa Corporation | Non-stochastic generation of genetic vaccines |
| US6713279B1 (en) | 1995-12-07 | 2004-03-30 | Diversa Corporation | Non-stochastic generation of genetic vaccines and enzymes |
| US6306387B1 (en) | 1997-05-29 | 2001-10-23 | The Research Foundation Of State University Of New York | Antigen delivery system |
| US20030045492A1 (en) | 1997-08-13 | 2003-03-06 | Tang De-Chu C. | Vaccination by topical application of recombinant vectors |
| US6969609B1 (en) | 1998-12-09 | 2005-11-29 | The United States Of America As Represented By The Department Of Health And Human Serivces | Recombinant vector expressing multiple costimulatory molecules and uses thereof |
| CA2223225A1 (en) | 1997-11-28 | 1999-05-28 | Canadian Red Cross Society | Method for inhibiting in vivo immune response |
| EP1059932A1 (en) | 1997-12-19 | 2000-12-20 | Immunex Corporation | Method for reducing susceptibility to hiv infection |
| GB9806449D0 (en) | 1998-03-25 | 1998-05-27 | Peptide Therapeutics Ltd | Attenuated bacteria useful in vaccines |
| US6190669B1 (en) | 1998-05-13 | 2001-02-20 | University Of Maryland, Baltimore | Attenuated mutants of salmonella which constitutively express the Vi antigen |
| IT1299583B1 (it) | 1998-05-19 | 2000-03-16 | Vander Way Limited | Uso di proteine hmg-i per la preparazione di medicamenti ad attivita' citotossica |
| ATE403728T1 (de) | 1998-09-04 | 2008-08-15 | Emergent Product Dev Uk Ltd | Attenuierte salmonella spi2 mutante als antigen- träger |
| US7300774B1 (en) | 1999-12-09 | 2007-11-27 | The Regents Of The University Of California | Multimeric fusion proteins of the TNF superfamily ligands |
| EP1067194A1 (en) | 1999-04-16 | 2001-01-10 | F. Hoffmann-La Roche Ag | Vectors containing a gene coding for CD40 and/or CD40L under the control of a cytokine-inducible promoter which is a human acute phase amyloid A gene promoter. Methods for their production and uses thereof |
| IL144952A0 (en) | 1999-04-16 | 2002-06-30 | Hoffmann La Roche | Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof |
| US7803765B2 (en) | 1999-05-05 | 2010-09-28 | Phylogica Limited | Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom |
| US7118751B1 (en) | 1999-10-14 | 2006-10-10 | Trubion Pharmaceuticals, Inc. | DNA vaccines encoding antigen linked to a domain that binds CD40 |
| DK1112747T3 (da) | 1999-12-28 | 2004-10-25 | Akzo Nobel Nv | Salmonellavaccine, som ikke inducerer antistoffer mod flagellin eller flageller |
| EP1255560B1 (en) | 2000-02-02 | 2008-10-29 | UNITED STATES GOVERNMENT as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE | Cd40 ligand adjuvant for respiratory syncytial virus vaccine |
| BR0109322A (pt) | 2000-03-17 | 2002-12-10 | Upjohn Co | Materiais e métodos de vacina de salmonella |
| GB0015426D0 (en) | 2000-06-24 | 2000-08-16 | Univ Southampton | Method for generating soluble highly multimeric proteins |
| WO2002000232A2 (en) | 2000-06-26 | 2002-01-03 | Maxygen, Inc. | Methods and compositions for developing spore display systems for medicinal and industrial applications |
| AU2002221780A1 (en) | 2000-10-31 | 2002-05-15 | F.Hoffmann-La Roche Ag | Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof |
| ATE438710T1 (de) | 2001-05-15 | 2009-08-15 | Ortho Mcneil Janssen Pharm | Ex-vivo-priming zur erzeugung cd40-ligand spezifischer zytotoxischer t-lymphozyten zur behandlung von autoimmun- und allergischen erkrankungen |
| US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| BR0209689A (pt) | 2001-05-15 | 2006-02-07 | Long Island Jewish Res Inst | Uso de fragmento de hmg como agente anti-inflamatório |
| ZA200400479B (en) | 2001-07-06 | 2006-05-31 | Abic Biolog Lab Teva | Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use |
| US7462707B1 (en) | 2001-07-06 | 2008-12-09 | University Of Technology, Sydney | Nucleic acids encoding a recombinant 250 kDa antigen from sporozoites/merozoites of Eimeria maxima and their uses |
| ITMI20011986A1 (it) | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
| WO2003028441A1 (en) | 2001-10-02 | 2003-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Gene therapy for the prevention of autoimmune disease |
| ATE395602T1 (de) | 2001-12-19 | 2008-05-15 | Alcedo Biotech Gmbh | Verwendung von hmgb-proteinen und dafür codierenden nukleinsäuren |
| AU2002359780B2 (en) | 2001-12-21 | 2009-08-13 | Immunex Corporation | Recombinant polypeptides |
| ATE421249T1 (de) | 2002-02-13 | 2009-02-15 | Immunology Lab Inc | Zusammensetzungen und verfahren für die behandlung von mikroorganismen-infektionen |
| US6923958B2 (en) | 2002-03-02 | 2005-08-02 | The Scripps Research Institute | DNA vaccines encoding CEA and a CD40 ligand and methods of use thereof |
| EP2380440B1 (en) | 2002-04-15 | 2016-03-09 | Washington University | Regulated attenuation of live vaccines to enhance cross protective immunogenicity |
| US7495090B2 (en) | 2002-05-23 | 2009-02-24 | The Regents Of The University Of California | Nucleic acids encoding chimeric CD154 polypeptides |
| US20040156851A1 (en) | 2002-11-20 | 2004-08-12 | Critical Therapeutics, Inc. | HMGB1 combination therapies |
| JP2006510619A (ja) | 2002-11-20 | 2006-03-30 | クリティカル セラピューティクス,インコーポレイテッド | 抗炎症剤としてのhmgb断片の使用 |
| US20040141948A1 (en) | 2002-11-20 | 2004-07-22 | Critical Therapeutics, Inc. | Use of HMGB fragments as anti-inflammatory agents |
| WO2004046338A2 (en) | 2002-11-20 | 2004-06-03 | North Shore-Long Island Jewish Research Institute | Use of hmgb polypeptides for increasing immune responses |
| US20060014248A1 (en) | 2003-01-06 | 2006-01-19 | Xencor, Inc. | TNF super family members with altered immunogenicity |
| US20050181994A1 (en) | 2003-01-06 | 2005-08-18 | Xencor, Inc. | Novel variants of CD40L protein |
| US7696169B2 (en) | 2003-06-06 | 2010-04-13 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| US7754209B2 (en) | 2003-07-26 | 2010-07-13 | Trubion Pharmaceuticals | Binding constructs and methods for use thereof |
| WO2005025604A2 (en) | 2003-09-10 | 2005-03-24 | The General Hospital Corporation | Use of hmgb and hmgb fragments to decrease specific immune response |
| EP1673389A2 (en) | 2003-10-10 | 2006-06-28 | Xencor Inc. | Novel variants of cd40l protein |
| US8828957B2 (en) | 2003-12-11 | 2014-09-09 | Microvax, Llc | Methods for generating immunity to antigen |
| CA2548347A1 (en) | 2003-12-11 | 2005-06-30 | Sidney Kimmel Cancer Center | Methods for generating immunity to antigen |
| WO2005113598A2 (en) | 2004-05-21 | 2005-12-01 | Xencor, Inc. | Tnf super family members with altered immunogenicity |
| US20080305120A1 (en) | 2004-06-17 | 2008-12-11 | Medimmune, Inc. | Immunogenic Compositions Comprising Hmgb 1 Polypeptides |
| WO2006012373A2 (en) | 2004-07-20 | 2006-02-02 | Critical Therapeutics, Inc. | Combination therapies of hmgb and complement inhibitors against inflammation |
| US20090011426A1 (en) * | 2004-08-19 | 2009-01-08 | Mackintosh James A | Methods of Diagnosis and Treatment of M.Tuberculosis Infection and Reagents Therefor |
| US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
| DE602005025005D1 (de) | 2004-10-07 | 2011-01-05 | Argos Therapeutics Inc | Zusammensetzungen reifer dendritischer zellen und verfahren zu deren kultivierung |
| WO2006105972A1 (en) | 2005-04-07 | 2006-10-12 | Universite Libre De Bruxelles | Transgenic organism expressing cd40l and uses thereof |
| US7833979B2 (en) * | 2005-04-22 | 2010-11-16 | Amgen Inc. | Toxin peptide therapeutic agents |
| US20060286074A1 (en) | 2005-05-31 | 2006-12-21 | Yucheng Tang | Methods for immunotherapy of cancer |
| WO2007011606A2 (en) | 2005-07-18 | 2007-01-25 | Critical Therapeutics, Inc. | USE OF HMGBl ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS |
| PT1949913E (pt) | 2005-10-07 | 2010-08-24 | Proyecto Biomedicina Cima Sl | Associação imunoestimuladora para a profilaxia e o tratamento da hepatite c |
| AU2006311752A1 (en) | 2005-11-07 | 2007-05-18 | Sidney Kimmel Cancer Center | CD40 ligand fusion protein vaccine |
| WO2007054658A1 (en) | 2005-11-14 | 2007-05-18 | King's College London | Control of immune responses |
| WO2007130725A2 (en) | 2006-02-06 | 2007-11-15 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of hmgb1 for protection against ischemia reperfusion injury |
| WO2007103048A2 (en) | 2006-03-01 | 2007-09-13 | Regents Of The University Of Colorado | Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity |
| WO2007106073A2 (en) | 2006-03-02 | 2007-09-20 | University Of Massachusetts | Modified pathogens for use as vaccines |
| EP2517723B1 (en) | 2006-09-18 | 2019-11-06 | The Board of Trustees of The University of Arkansas | Compositions and methods of enhancing immune responses |
| US20100292309A1 (en) | 2007-03-08 | 2010-11-18 | Mayo Foundation For Medical Education And Research | Inducing immune-mediated tumor cell death |
| CN101024076B (zh) | 2007-03-29 | 2010-08-18 | 中国农业大学 | 球虫的新用途 |
| BRPI0818736A2 (pt) | 2007-10-30 | 2017-06-13 | Univ Arkansas | composições e métodos para intensificar imunorrepostas à bactéria flagelada |
| WO2009059298A2 (en) | 2007-11-01 | 2009-05-07 | Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancinc immune responses to eimeria |
| CN101234196A (zh) | 2007-11-30 | 2008-08-06 | 吉林大学 | 球虫重组卡介苗及制备方法 |
| BRPI0916349A2 (pt) | 2008-09-11 | 2019-09-24 | Pasteur Institut | monitoramento e inibição da infecção pelo vírus da imunodeficiência humana através da modulação do desencadeamento dependete de hmgb1 da replicação e persistência do hiv-1 |
| CA2743262C (en) | 2008-11-13 | 2021-11-02 | Intervet International B.V. | Eimeria vaccine for turkeys |
| US20100150958A1 (en) | 2008-12-15 | 2010-06-17 | Vectogen Pty Ltd. | Methods and Compositions for Use of a Coccidiosis Vaccine |
| JP2011072284A (ja) * | 2009-10-01 | 2011-04-14 | Mitsubishi Chemicals Corp | 抗体の製造方法及びそれに用いる免疫原性組成物 |
| CN102811734B (zh) | 2010-01-21 | 2016-02-10 | 阿肯色大学评议会 | 增强免疫应答的疫苗载体和方法 |
| CA2800830C (en) | 2010-06-09 | 2020-09-08 | The Board Of Trustees Of The University Of Arkansas | Vaccine and methods to reduce campylobacter infection |
| EA031234B1 (ru) | 2012-10-29 | 2018-12-28 | Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Арканзас | Вакцина с адъювантом на основе маннозилированного хитозана |
| HUE047484T2 (hu) | 2013-02-14 | 2020-04-28 | Univ Arkansas | Készítmények és eljárások eimeria elleni immunválasz fokozására vagy eimeria-fertõzés korlátozására |
| US10376571B2 (en) | 2013-03-15 | 2019-08-13 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancing immune responses to enteric pathogens |
-
2014
- 2014-02-14 HU HUE14751914A patent/HUE047484T2/hu unknown
- 2014-02-14 EA EA201591488A patent/EA030929B1/ru unknown
- 2014-02-14 CN CN201480021011.6A patent/CN105142665A/zh active Pending
- 2014-02-14 ES ES14751914T patent/ES2758759T3/es active Active
- 2014-02-14 DK DK14751914T patent/DK2956165T3/da active
- 2014-02-14 KR KR1020157024664A patent/KR102228324B1/ko not_active Expired - Fee Related
- 2014-02-14 AR ARP140100470A patent/AR094791A1/es active IP Right Grant
- 2014-02-14 US US14/768,011 patent/US9603915B2/en active Active
- 2014-02-14 PT PT147519144T patent/PT2956165T/pt unknown
- 2014-02-14 ES ES19194676T patent/ES2968398T3/es active Active
- 2014-02-14 CA CA2900644A patent/CA2900644C/en active Active
- 2014-02-14 NZ NZ711019A patent/NZ711019A/en not_active IP Right Cessation
- 2014-02-14 BR BR112015019283-1A patent/BR112015019283B1/pt active IP Right Grant
- 2014-02-14 WO PCT/US2014/016359 patent/WO2014127185A1/en not_active Ceased
- 2014-02-14 AU AU2014216246A patent/AU2014216246B2/en active Active
- 2014-02-14 PL PL14751914T patent/PL2956165T3/pl unknown
- 2014-02-14 EP EP19194676.3A patent/EP3610887B8/en active Active
- 2014-02-14 EP EP14751914.4A patent/EP2956165B1/en active Active
- 2014-02-14 SG SG10202109925T patent/SG10202109925TA/en unknown
- 2014-02-14 MY MYPI2018001432A patent/MY200497A/en unknown
- 2014-02-14 JP JP2015558140A patent/JP6532407B2/ja not_active Expired - Fee Related
- 2014-02-14 MX MX2015010555A patent/MX2015010555A/es active IP Right Grant
- 2014-02-14 CN CN202010782256.8A patent/CN111956796B/zh active Active
- 2014-02-14 MY MYPI2015002038A patent/MY173328A/en unknown
- 2014-02-14 SG SG11201506398SA patent/SG11201506398SA/en unknown
-
2015
- 2015-08-05 ZA ZA2015/05638A patent/ZA201505638B/en unknown
- 2015-08-13 PH PH12015501784A patent/PH12015501784A1/en unknown
- 2015-08-14 CL CL2015002273A patent/CL2015002273A1/es unknown
-
2017
- 2017-03-06 US US15/450,138 patent/US9884099B2/en active Active
-
2018
- 2018-01-23 US US15/877,598 patent/US10328137B2/en active Active
-
2019
- 2019-02-18 JP JP2019026326A patent/JP6874031B2/ja not_active Expired - Fee Related
- 2019-06-12 US US16/439,511 patent/US10792351B2/en active Active
-
2020
- 2020-09-17 US US17/023,795 patent/US11364290B2/en active Active
-
2022
- 2022-05-25 US US17/824,378 patent/US11904005B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11904005B2 (en) | Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection | |
| KR102239207B1 (ko) | 장내 병원균에 대한 면역 반응을 증진시키는 조성물 및 방법 | |
| US11382962B2 (en) | Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same | |
| WO2011091255A1 (en) | Vaccine vectors and methods of enhancing immune responses | |
| JP2001522235A (ja) | ターゲッティング分子を用いた免疫応答の増強 | |
| Barta et al. | Compositions and methods of enhancing immune responses to Eimeria or limiting Eimeria infection | |
| HK1218880B (en) | Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection | |
| BR112012018027B1 (pt) | Vetores de vacina e métodos de aperfeiçoamento de respostas imunes |