ES2721305T3 - Cartucho de reactivos - Google Patents
Cartucho de reactivos Download PDFInfo
- Publication number
- ES2721305T3 ES2721305T3 ES15783819T ES15783819T ES2721305T3 ES 2721305 T3 ES2721305 T3 ES 2721305T3 ES 15783819 T ES15783819 T ES 15783819T ES 15783819 T ES15783819 T ES 15783819T ES 2721305 T3 ES2721305 T3 ES 2721305T3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/52—Containers specially adapted for storing or dispensing a reagent
- B01L3/523—Containers specially adapted for storing or dispensing a reagent with means for closing or opening
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/047—Additional chamber, reservoir
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/049—Valves integrated in closure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0672—Integrated piercing tool
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
- B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0325—Cells for testing reactions, e.g. containing reagents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0325—Cells for testing reactions, e.g. containing reagents
- G01N2021/0328—Arrangement of two or more cells having different functions for the measurement of reactions
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6443—Fluorimetric titration
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7769—Measurement method of reaction-produced change in sensor
- G01N2021/7786—Fluorescence
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
Abstract
Un aparato (1700, 2700, 3700, 4700), que comprende: - una carcasa (1741, 2741, 3741, 4741) configurada para acoplarse de manera extraíble a una cámara de reacción (1732, 2732, 3742, 4742), definiendo la carcasa un volumen de reactivos (1742, 2742, 3742, 4742) configurado para recibir un recipiente de reactivos (1780, 2780, 3780, 4780), incluyendo la carcasa un perforador (1792, 2792, 3792, 4792) que define una vía de transferencia (1793, 4793) en comunicación fluida con el volumen de reactivos, incluyendo la carcasa una parte de administración (1770, 2770, 3770, 4770) que define una vía de administración (1771, 2771, 3771, 4771) entre la vía de transferencia y la cámara de reacción cuando la carcasa está acoplada a la cámara de reacción; y - un accionador (1750, 2750, 3750, 4750) que tiene una parte de émbolo (1754, 2754, 3754, 4754) dispuesta dentro del volumen de reactivos, una parte de acoplamiento (1752, 2752, 3752, 4752) del accionador configurada para manipularla para mover la parte de émbolo dentro del volumen de reactivos para deformar el recipiente de reactivos, configurado el perforador para perforar una parte frangible (1788, 2788, 3788, 4788) del recipiente de reactivos para transportar un reactivo desde el recipiente de reactivos a la cámara de reacción por medio de la vía de transferencia y la vía de administración, caracterizado por que - el perforador y la carcasa están construidos monolíticamente.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461983765P | 2014-04-24 | 2014-04-24 | |
US14/617,631 US9540675B2 (en) | 2013-10-29 | 2015-02-09 | Reagent cartridge and methods for detection of cells |
PCT/US2015/027519 WO2015164746A1 (en) | 2014-04-24 | 2015-04-24 | Reagent cartridge and methods for detection of cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2721305T3 true ES2721305T3 (es) | 2019-07-30 |
Family
ID=54333269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES15783819T Active ES2721305T3 (es) | 2014-04-24 | 2015-04-24 | Cartucho de reactivos |
Country Status (7)
Country | Link |
---|---|
US (2) | US9540675B2 (es) |
EP (2) | EP3524686A1 (es) |
JP (2) | JP6845014B2 (es) |
CN (2) | CN106461535B (es) |
CA (2) | CA2946752C (es) |
ES (1) | ES2721305T3 (es) |
WO (1) | WO2015164746A1 (es) |
Families Citing this family (30)
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US9481903B2 (en) | 2013-03-13 | 2016-11-01 | Roche Molecular Systems, Inc. | Systems and methods for detection of cells using engineered transduction particles |
US9540675B2 (en) | 2013-10-29 | 2017-01-10 | GeneWeave Biosciences, Inc. | Reagent cartridge and methods for detection of cells |
US9243222B2 (en) * | 2014-01-06 | 2016-01-26 | Lawrence Livermore National Security, Llc | Compositions and methods for pathogen transport |
ES2872526T3 (es) | 2014-06-13 | 2021-11-02 | Geneweave Biosciences Inc | Detección de células independiente del crecimiento |
US10227661B2 (en) | 2014-11-21 | 2019-03-12 | GeneWeave Biosciences, Inc. | Sequence-specific detection and phenotype determination |
US9879328B2 (en) | 2014-11-21 | 2018-01-30 | GeneWeave Biosciences, Inc. | Mechanisms of antimicrobial susceptibility |
US10351893B2 (en) | 2015-10-05 | 2019-07-16 | GeneWeave Biosciences, Inc. | Reagent cartridge for detection of cells |
US10718003B2 (en) | 2015-12-31 | 2020-07-21 | Roche Molecular Systems, Inc. | Detecting an analyte in a flash and glow reaction |
JP6627564B2 (ja) * | 2016-02-25 | 2020-01-08 | 株式会社島津製作所 | 反応容器及びそれを用いた試薬キット |
AU2017241592A1 (en) | 2016-03-28 | 2018-10-18 | The Charles Stark Draper Laboratory, Inc. | Bacteriophage engineering methods |
GB201615472D0 (en) | 2016-09-12 | 2016-10-26 | Fluidic Analytics Ltd | Improvements in or relating to a reagent cartridge |
US11149319B2 (en) * | 2016-12-20 | 2021-10-19 | Roche Molecular Systems, Inc. | Systems and methods for detecting cells using engineered transduction particles |
US10634591B2 (en) * | 2017-03-13 | 2020-04-28 | Tokitae Llc | Device for concentration of biological sample prior to immunoassay |
US11080848B2 (en) | 2017-04-06 | 2021-08-03 | Lucira Health, Inc. | Image-based disease diagnostics using a mobile device |
US11077444B2 (en) * | 2017-05-23 | 2021-08-03 | Roche Molecular Systems, Inc. | Packaging for a molecular diagnostic cartridge |
CN108359639B (zh) * | 2018-01-24 | 2020-10-23 | 杭州安弼晟生物科技有限公司 | 一种循环肿瘤细胞捕获系统 |
LU100716B1 (en) * | 2018-02-26 | 2019-08-28 | Stratec Biomedical Ag | Assay components for diagnostic in vitro applications |
JP2022511694A (ja) * | 2018-11-12 | 2022-02-01 | ゲーカーエー ゲーエムベーハー | プロセスチャレンジデバイスで使用されるテーパ状インジケータ |
US10968491B2 (en) | 2018-12-05 | 2021-04-06 | GeneWeave Biosciences, Inc. | Growth-independent detection of cells |
BR112021009432A2 (pt) * | 2018-12-10 | 2021-08-17 | Laboratory Corporation Of America Holdings | aparelho autônomo e sistema para a detecção de micro-organismos. |
JP2022515833A (ja) * | 2018-12-29 | 2022-02-22 | エフ.ホフマン-ラ ロシュ アーゲー | 抗生物質感受性アッセイにおける交差反応性の制限および細菌同定の改善のためのシデロマイシンの使用 |
SG10201900431QA (en) * | 2019-01-17 | 2020-08-28 | Toku E Biotech Laboratory Pte Ltd | A sterile reagent preparation device and the method of using the same |
JP7344540B2 (ja) * | 2019-06-19 | 2023-09-14 | 株式会社Icst | 試験器具および試験方法 |
CA3175910A1 (en) * | 2020-03-17 | 2021-09-23 | Detect, Inc. | Reagent carrier for rapid diagnostic tests |
CN114100702B (zh) * | 2020-08-27 | 2023-05-30 | 京东方科技集团股份有限公司 | 一种检测芯片及其制备方法、使用方法、检测装置 |
WO2022085001A2 (en) * | 2020-10-20 | 2022-04-28 | Rapid Diagnostic Systems Ltd | Systems and kits for facilitating rapid diagnosis of infectious diseases |
CN114100711B (zh) * | 2021-11-17 | 2022-11-29 | 江苏液滴逻辑生物技术有限公司 | 一种芯片试剂的包装、预埋与注样装置及方法与用途 |
CN114100712A (zh) * | 2021-11-19 | 2022-03-01 | 江苏液滴逻辑生物技术有限公司 | 一种微流控芯片的孔注液装置、及其注液方法和用途 |
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- 2015-02-09 US US14/617,631 patent/US9540675B2/en active Active
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EP3134722B1 (en) | 2019-02-20 |
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US10125386B2 (en) | 2018-11-13 |
JP2017513496A (ja) | 2017-06-01 |
CA2946752A1 (en) | 2015-10-29 |
US9540675B2 (en) | 2017-01-10 |
EP3134722A1 (en) | 2017-03-01 |
US20150218613A1 (en) | 2015-08-06 |
CA3074506A1 (en) | 2015-10-29 |
US20170233783A1 (en) | 2017-08-17 |
CN106461535B (zh) | 2019-07-12 |
CA3074506C (en) | 2021-03-30 |
EP3524686A1 (en) | 2019-08-14 |
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