ES2705027T3 - Métodos de tratamiento del deterioro cognitivo leve (DCL) y trastornos relacionados - Google Patents

Métodos de tratamiento del deterioro cognitivo leve (DCL) y trastornos relacionados Download PDF

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Publication number
ES2705027T3
ES2705027T3 ES11818848T ES11818848T ES2705027T3 ES 2705027 T3 ES2705027 T3 ES 2705027T3 ES 11818848 T ES11818848 T ES 11818848T ES 11818848 T ES11818848 T ES 11818848T ES 2705027 T3 ES2705027 T3 ES 2705027T3
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Prior art keywords
compound
disease
mammal
administration
alzheimer
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Application number
ES11818848T
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English (en)
Spanish (es)
Inventor
Varghese John
Dale E Bredesen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Buck Institute For Age Res
Buck Institute for Research on Aging
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Buck Institute For Age Res
Buck Institute for Research on Aging
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES11818848T 2010-08-19 2011-08-19 Métodos de tratamiento del deterioro cognitivo leve (DCL) y trastornos relacionados Active ES2705027T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40190710P 2010-08-19 2010-08-19
PCT/US2011/048472 WO2012024616A1 (en) 2010-08-19 2011-08-19 Methods of treating miild cognitive impairment (mci) and related discorders

Publications (1)

Publication Number Publication Date
ES2705027T3 true ES2705027T3 (es) 2019-03-21

Family

ID=45605447

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11818848T Active ES2705027T3 (es) 2010-08-19 2011-08-19 Métodos de tratamiento del deterioro cognitivo leve (DCL) y trastornos relacionados

Country Status (10)

Country Link
US (1) US10449177B2 (https=)
EP (1) EP2605655B1 (https=)
JP (2) JP6250394B2 (https=)
AU (1) AU2011291506B2 (https=)
BR (1) BR112013003847A8 (https=)
CA (1) CA2808630A1 (https=)
DK (1) DK2605655T3 (https=)
ES (1) ES2705027T3 (https=)
MX (1) MX353096B (https=)
WO (1) WO2012024616A1 (https=)

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Also Published As

Publication number Publication date
JP2016193944A (ja) 2016-11-17
EP2605655A4 (en) 2014-01-08
MX353096B (es) 2017-12-19
CA2808630A1 (en) 2012-02-23
BR112013003847A2 (pt) 2016-05-31
JP2013534256A (ja) 2013-09-02
AU2011291506A1 (en) 2013-03-14
AU2011291506B2 (en) 2016-07-28
EP2605655A1 (en) 2013-06-26
US10449177B2 (en) 2019-10-22
EP2605655B1 (en) 2018-10-24
JP6250394B2 (ja) 2017-12-20
BR112013003847A8 (pt) 2017-12-26
DK2605655T3 (en) 2019-02-04
WO2012024616A1 (en) 2012-02-23
MX2013001917A (es) 2013-10-25
US20120071468A1 (en) 2012-03-22

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