BR112013003847A8 - métodos de tratar a deterioração cognitiva moderada (mci) e os distúrbios relacionados - Google Patents
métodos de tratar a deterioração cognitiva moderada (mci) e os distúrbios relacionadosInfo
- Publication number
- BR112013003847A8 BR112013003847A8 BR112013003847A BR112013003847A BR112013003847A8 BR 112013003847 A8 BR112013003847 A8 BR 112013003847A8 BR 112013003847 A BR112013003847 A BR 112013003847A BR 112013003847 A BR112013003847 A BR 112013003847A BR 112013003847 A8 BR112013003847 A8 BR 112013003847A8
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- mci
- cognitive impairment
- treating moderate
- related disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40190710P | 2010-08-19 | 2010-08-19 | |
| PCT/US2011/048472 WO2012024616A1 (en) | 2010-08-19 | 2011-08-19 | Methods of treating miild cognitive impairment (mci) and related discorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013003847A2 BR112013003847A2 (pt) | 2016-05-31 |
| BR112013003847A8 true BR112013003847A8 (pt) | 2017-12-26 |
Family
ID=45605447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013003847A BR112013003847A8 (pt) | 2010-08-19 | 2011-08-19 | métodos de tratar a deterioração cognitiva moderada (mci) e os distúrbios relacionados |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10449177B2 (https=) |
| EP (1) | EP2605655B1 (https=) |
| JP (2) | JP6250394B2 (https=) |
| AU (1) | AU2011291506B2 (https=) |
| BR (1) | BR112013003847A8 (https=) |
| CA (1) | CA2808630A1 (https=) |
| DK (1) | DK2605655T3 (https=) |
| ES (1) | ES2705027T3 (https=) |
| MX (1) | MX353096B (https=) |
| WO (1) | WO2012024616A1 (https=) |
Families Citing this family (17)
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| JP6250394B2 (ja) | 2010-08-19 | 2017-12-20 | バック・インスティテュート・フォー・リサーチ・オン・エイジング | 軽度の認知障害（ｍｃｉ）および関連障害の処置方法 |
| AU2013299656C1 (en) | 2012-08-07 | 2017-06-22 | Buck Institute For Research On Aging | Multi-component formulation for improving neurological function |
| US20140371283A1 (en) | 2013-02-12 | 2014-12-18 | Buck Institute For Research On Aging | Hydantoins that modulate bace-mediated app processing |
| WO2014152207A1 (en) | 2013-03-15 | 2014-09-25 | Mylan Laboratories, Inc. | Hot melt granulation formulations of poorly water-soluble active agents |
| AU2015211021B2 (en) | 2014-01-28 | 2020-07-02 | Buck Institute For Research On Aging | Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders |
| US20170216286A1 (en) | 2014-01-28 | 2017-08-03 | Mayo Foundation For Medical Education And Research | Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoid |
| CA2941415A1 (en) | 2014-03-21 | 2015-09-24 | Alzheon, Inc. | Methods for treating neurological disorders |
| KR102220260B1 (ko) | 2015-02-18 | 2021-02-25 | 버크 인스티튜트 포 리서치 온 에이징 | 스트레스-유도성 p-tau 를 낮추는 트리아졸로피리딘 및 트리아졸로피리미딘 |
| WO2016187339A1 (en) * | 2015-05-18 | 2016-11-24 | Synaptec Development Llc | GALANTAMINE CLEARANCE OF AMYLOIDß |
| FI3347002T3 (fi) | 2015-09-10 | 2023-08-10 | Alzheon Inc | Alzheimerin taudin hoitaminen tietyssä potilaspopulaatiossa |
| CA3007641C (en) | 2015-12-09 | 2023-10-17 | Brandeis University | Dbh inhibitors for treating or preventing memory loss |
| US20180250249A1 (en) * | 2016-02-02 | 2018-09-06 | Alzheon, Inc. | Methods of treating neurodegenerative disorders in a particular population |
| IL262957B2 (en) | 2016-05-12 | 2024-04-01 | Buck Inst Res Aging | 6-Fluorotropistrone and a pharmaceutical formulation comprising it for the relief of amyloid-related diseases |
| MX2019007981A (es) | 2017-01-03 | 2019-10-15 | Bioatla Llc | Terapeutica de proteinas para el tratamiento de celulas senescentes. |
| IL312612A (en) | 2018-07-11 | 2024-07-01 | Rubedo Life Sciences Inc | Senolytic compositions and uses thereof |
| CN110232679A (zh) * | 2019-05-24 | 2019-09-13 | 潘丹 | 一种阿尔茨海默症遗传生物标志物确定方法及系统 |
| US12521362B2 (en) | 2019-07-25 | 2026-01-13 | Tokyo University Of Science Foundation | Agent for treating, preventing, or improving psychiatric and nervous system disorders or symptoms |
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| EP2814491A4 (en) | 2012-02-18 | 2015-08-26 | Buck Inst For Res On Aging | FORMULATIONS AND METHODS FOR TREATING OR PROPHYLAXIS OF PRE-MCI AND / OR PRE-ALZHEIMER ILLNESSES |
-
2011
- 2011-08-19 JP JP2013525003A patent/JP6250394B2/ja active Active
- 2011-08-19 DK DK11818848.1T patent/DK2605655T3/en active
- 2011-08-19 ES ES11818848T patent/ES2705027T3/es active Active
- 2011-08-19 US US13/213,960 patent/US10449177B2/en active Active
- 2011-08-19 BR BR112013003847A patent/BR112013003847A8/pt not_active IP Right Cessation
- 2011-08-19 MX MX2013001917A patent/MX353096B/es active IP Right Grant
- 2011-08-19 WO PCT/US2011/048472 patent/WO2012024616A1/en not_active Ceased
- 2011-08-19 EP EP11818848.1A patent/EP2605655B1/en active Active
- 2011-08-19 CA CA2808630A patent/CA2808630A1/en not_active Abandoned
- 2011-08-19 AU AU2011291506A patent/AU2011291506B2/en not_active Ceased
-
2016
- 2016-08-18 JP JP2016160482A patent/JP2016193944A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016193944A (ja) | 2016-11-17 |
| EP2605655A4 (en) | 2014-01-08 |
| MX353096B (es) | 2017-12-19 |
| CA2808630A1 (en) | 2012-02-23 |
| BR112013003847A2 (pt) | 2016-05-31 |
| JP2013534256A (ja) | 2013-09-02 |
| AU2011291506A1 (en) | 2013-03-14 |
| AU2011291506B2 (en) | 2016-07-28 |
| ES2705027T3 (es) | 2019-03-21 |
| EP2605655A1 (en) | 2013-06-26 |
| US10449177B2 (en) | 2019-10-22 |
| EP2605655B1 (en) | 2018-10-24 |
| JP6250394B2 (ja) | 2017-12-20 |
| DK2605655T3 (en) | 2019-02-04 |
| WO2012024616A1 (en) | 2012-02-23 |
| MX2013001917A (es) | 2013-10-25 |
| US20120071468A1 (en) | 2012-03-22 |
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