JP6250394B2 - 軽度の認知障害（ｍｃｉ）および関連障害の処置方法 - Google Patents

軽度の認知障害（ｍｃｉ）および関連障害の処置方法 Download PDF

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JP6250394B2
JP6250394B2 JP2013525003A JP2013525003A JP6250394B2 JP 6250394 B2 JP6250394 B2 JP 6250394B2 JP 2013525003 A JP2013525003 A JP 2013525003A JP 2013525003 A JP2013525003 A JP 2013525003A JP 6250394 B2 JP6250394 B2 JP 6250394B2
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alzheimer
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JP2013534256A (ja
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ヴァーゲス・ジョン
デイル・イー・ブレーデセン
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バック・インスティテュート・フォー・リサーチ・オン・エイジング
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013525003A 2010-08-19 2011-08-19 軽度の認知障害（ｍｃｉ）および関連障害の処置方法 Active JP6250394B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40190710P 2010-08-19 2010-08-19
US61/401,907 2010-08-19
PCT/US2011/048472 WO2012024616A1 (en) 2010-08-19 2011-08-19 Methods of treating miild cognitive impairment (mci) and related discorders

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JP2016160482A Division JP2016193944A (ja) 2010-08-19 2016-08-18 軽度の認知障害（ｍｃｉ）および関連障害の処置方法

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JP2013534256A JP2013534256A (ja) 2013-09-02
JP2013534256A5 JP2013534256A5 (https=) 2014-10-09
JP6250394B2 true JP6250394B2 (ja) 2017-12-20

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JP2016160482A Pending JP2016193944A (ja) 2010-08-19 2016-08-18 軽度の認知障害（ｍｃｉ）および関連障害の処置方法

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US (1) US10449177B2 (https=)
EP (1) EP2605655B1 (https=)
JP (2) JP6250394B2 (https=)
AU (1) AU2011291506B2 (https=)
BR (1) BR112013003847A8 (https=)
CA (1) CA2808630A1 (https=)
DK (1) DK2605655T3 (https=)
ES (1) ES2705027T3 (https=)
MX (1) MX353096B (https=)
WO (1) WO2012024616A1 (https=)

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Also Published As

Publication number Publication date
JP2016193944A (ja) 2016-11-17
EP2605655A4 (en) 2014-01-08
MX353096B (es) 2017-12-19
CA2808630A1 (en) 2012-02-23
BR112013003847A2 (pt) 2016-05-31
JP2013534256A (ja) 2013-09-02
AU2011291506A1 (en) 2013-03-14
AU2011291506B2 (en) 2016-07-28
ES2705027T3 (es) 2019-03-21
EP2605655A1 (en) 2013-06-26
US10449177B2 (en) 2019-10-22
EP2605655B1 (en) 2018-10-24
BR112013003847A8 (pt) 2017-12-26
DK2605655T3 (en) 2019-02-04
WO2012024616A1 (en) 2012-02-23
MX2013001917A (es) 2013-10-25
US20120071468A1 (en) 2012-03-22

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