ES2704440T3 - Formulaciones de anticuerpos y métodos - Google Patents
Formulaciones de anticuerpos y métodos Download PDFInfo
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- ES2704440T3 ES2704440T3 ES14752412T ES14752412T ES2704440T3 ES 2704440 T3 ES2704440 T3 ES 2704440T3 ES 14752412 T ES14752412 T ES 14752412T ES 14752412 T ES14752412 T ES 14752412T ES 2704440 T3 ES2704440 T3 ES 2704440T3
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
- Health & Medical Sciences (AREA)
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- Hospice & Palliative Care (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Analytical Chemistry (AREA)
- Inorganic Chemistry (AREA)
Applications Claiming Priority (3)
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| US201461979886P | 2014-04-15 | 2014-04-15 | |
| PCT/IB2014/062806 WO2015001504A2 (en) | 2013-07-04 | 2014-07-03 | Antibody formulations and methods |
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| EP3378535B1 (en) | 2011-10-28 | 2023-01-04 | Prothena Biosciences Limited | Humanized antibodies that recognize alpha-synuclein |
| KR102086061B1 (ko) | 2012-01-27 | 2020-03-11 | 프로테나 바이오사이언시즈 리미티드 | 알파-시누클레인을 인식하는 인간화된 항체 |
| UA118441C2 (uk) | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| US10513555B2 (en) | 2013-07-04 | 2019-12-24 | Prothena Biosciences Limited | Antibody formulations and methods |
| WO2015155694A1 (en) | 2014-04-08 | 2015-10-15 | Prothena Biosciences Limited | Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein |
| GB201512203D0 (en) | 2015-07-13 | 2015-08-19 | Lundbeck & Co As H | Agents,uses and methods |
| LT3334747T (lt) | 2015-08-13 | 2023-12-27 | Amgen Inc. | Įkrautas giluminis antigeną surišančio baltymo filtravimas |
| JP6921062B2 (ja) * | 2015-09-28 | 2021-08-18 | スーヂョウ サンケイディア バイオファーマスーティカルズ カンパニー リミテッド | 安定な抗ｐｄ−１抗体医薬製剤および医薬におけるその適用 |
| CN105127166A (zh) * | 2015-09-29 | 2015-12-09 | 中国华能集团清洁能源技术研究院有限公司 | 行走组件及具有其的光伏组件清洁装置 |
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| JP7217229B2 (ja) | 2016-11-15 | 2023-02-02 | ハー・ルンドベック・アクチエゼルスカベット | シヌクレイノパチーの治療のための薬剤、使用および方法 |
| ES3008133T3 (en) | 2016-12-16 | 2025-03-21 | H Lundbeck As | Agents, uses and methods |
| US10364286B2 (en) | 2016-12-22 | 2019-07-30 | H. Lundbeck A/S | Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation |
| US11142570B2 (en) | 2017-02-17 | 2021-10-12 | Bristol-Myers Squibb Company | Antibodies to alpha-synuclein and uses thereof |
| CA3076313A1 (en) * | 2017-09-28 | 2019-04-04 | Prothena Biosciences Limited | Dosing regimes for treatment of synucleinopathies |
| US20190153102A1 (en) * | 2017-09-28 | 2019-05-23 | Prothena Biosciences Limited | Dosing regimes for treatment of synucleinopathies |
| GB201720970D0 (en) | 2017-12-15 | 2018-01-31 | Ucb Biopharma Sprl | Antibodies |
| JP6831861B2 (ja) | 2019-01-25 | 2021-02-17 | 株式会社Ｇｒｉｎ | 歯科用測定器具、測定方法、及びアタッチメント器具 |
| JP7266108B2 (ja) | 2019-02-18 | 2023-04-27 | イーライ リリー アンド カンパニー | 治療用抗体製剤 |
| EP3786174A1 (en) * | 2019-08-27 | 2021-03-03 | Ichnos Sciences SA | Methods for antibody purification |
| GB2587228B (en) * | 2019-09-20 | 2021-10-27 | Protein Ark Ltd | Biological sample purification apparatus, use of the same, and systems comprising the same |
| WO2022020680A1 (en) | 2020-07-23 | 2022-01-27 | Othair Prothena Limited | Anti-abeta antibodies |
| TW202227131A (zh) | 2020-09-10 | 2022-07-16 | 愛爾蘭商普羅佘納生物科技有限公司 | 帕金森氏症之治療 |
| CN114516914B (zh) * | 2020-11-19 | 2023-04-28 | 东莞市朋志生物科技有限公司 | 抗n末端脑钠肽前体的抗体和检测n末端脑钠肽前体的试剂和试剂盒 |
| EP4401770A2 (en) | 2021-09-16 | 2024-07-24 | H. Lundbeck A/S | Compositions and methods for treating synucleinopathies |
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| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| EP0307434B2 (en) | 1987-03-18 | 1998-07-29 | Scotgen Biopharmaceuticals, Inc. | Altered antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| IE64738B1 (en) | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
| DE122004000008I1 (de) | 1991-06-14 | 2005-06-09 | Genentech Inc | Humanisierter Heregulin Antikörper. |
| US5786464C1 (en) | 1994-09-19 | 2012-04-24 | Gen Hospital Corp | Overexpression of mammalian and viral proteins |
| AU695129B2 (en) | 1995-02-06 | 1998-08-06 | Genetics Institute, Llc | Formulations for IL-12 |
| DE19539493A1 (de) | 1995-10-24 | 1997-04-30 | Thomae Gmbh Dr K | Starker homologer Promotor aus Hamster |
| US5834597A (en) | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6114148C1 (en) | 1996-09-20 | 2012-05-01 | Gen Hospital Corp | High level expression of proteins |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| ATE490518T1 (de) | 1999-02-05 | 2010-12-15 | Samsung Electronics Co Ltd | Verfahren und vorrichtung zum wiederauffinden von texturbildern |
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-
2014
- 2014-07-02 US US14/322,797 patent/US10513555B2/en active Active
- 2014-07-03 WO PCT/IB2014/062806 patent/WO2015001504A2/en not_active Ceased
- 2014-07-03 RU RU2016103079A patent/RU2016103079A/ru not_active Application Discontinuation
- 2014-07-03 ES ES14752412T patent/ES2704440T3/es active Active
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- 2014-07-03 EP EP14752412.8A patent/EP3016677B1/en active Active
- 2014-07-03 PE PE2015002708A patent/PE20160868A1/es not_active Application Discontinuation
- 2014-07-03 CU CUP2017000039A patent/CU20170039A7/es unknown
- 2014-07-03 CN CN201480047476.9A patent/CN105492019B/zh active Active
- 2014-07-03 CA CA2917097A patent/CA2917097C/en active Active
- 2014-07-03 AU AU2014285719A patent/AU2014285719A1/en not_active Abandoned
- 2014-07-03 JP JP2016522950A patent/JP6404338B2/ja active Active
- 2014-07-03 KR KR1020167003163A patent/KR20160030247A/ko not_active Withdrawn
- 2014-07-03 EP EP18212531.0A patent/EP3524264A1/en active Pending
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2015
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- 2015-12-31 CL CL2015003801A patent/CL2015003801A1/es unknown
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|---|---|
| JP6404338B2 (ja) | 2018-10-10 |
| SG11201510601TA (en) | 2016-01-28 |
| JP2019011339A (ja) | 2019-01-24 |
| EP3524264A1 (en) | 2019-08-14 |
| US10513555B2 (en) | 2019-12-24 |
| US20150079074A1 (en) | 2015-03-19 |
| JP6854266B2 (ja) | 2021-04-07 |
| KR20160030247A (ko) | 2016-03-16 |
| WO2015001504A2 (en) | 2015-01-08 |
| HK1223544A1 (zh) | 2017-08-04 |
| CN105492019B (zh) | 2020-02-11 |
| IL243425A0 (en) | 2016-03-31 |
| EP3016677B1 (en) | 2018-12-19 |
| CU20170039A7 (es) | 2017-06-05 |
| US20200140534A1 (en) | 2020-05-07 |
| CN105492019A (zh) | 2016-04-13 |
| CL2015003801A1 (es) | 2016-07-15 |
| CA2917097C (en) | 2022-05-03 |
| RU2016103079A (ru) | 2017-08-07 |
| PH12015502788A1 (en) | 2016-03-21 |
| EP3016677A2 (en) | 2016-05-11 |
| PE20160868A1 (es) | 2016-09-24 |
| CA2917097A1 (en) | 2015-01-08 |
| CU20160001A7 (es) | 2016-08-31 |
| JP2016534052A (ja) | 2016-11-04 |
| AU2014285719A1 (en) | 2016-01-21 |
| MX2016000201A (es) | 2016-05-31 |
| WO2015001504A3 (en) | 2015-08-06 |
| JP2021020941A (ja) | 2021-02-18 |
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