ES2687847T3 - Análisis mutacional de ADN de plasma para la detección de cáncer - Google Patents

Análisis mutacional de ADN de plasma para la detección de cáncer Download PDF

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Publication number
ES2687847T3
ES2687847T3 ES13807105.5T ES13807105T ES2687847T3 ES 2687847 T3 ES2687847 T3 ES 2687847T3 ES 13807105 T ES13807105 T ES 13807105T ES 2687847 T3 ES2687847 T3 ES 2687847T3
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sequence
tumor
dna
mutations
sequencing
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Wai Kwun Rossa CHIU
Yuk-Ming Dennis Lo
Kwan Chee CHAN
Peiyong Jiang
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Chinese University of Hong Kong CUHK
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
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    • C12Q2537/16—Assays for determining copy number or wherein the copy number is of special importance
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    • C12Q2539/00—Reactions characterised by analysis of gene expression or genome comparison
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  • Hospice & Palliative Care (AREA)
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  • General Physics & Mathematics (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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ES13807105.5T 2012-06-21 2013-06-14 Análisis mutacional de ADN de plasma para la detección de cáncer Active ES2687847T3 (es)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201261662878P 2012-06-21 2012-06-21
US201261662878P 2012-06-21
US201261682725P 2012-08-13 2012-08-13
US201261682725P 2012-08-13
US201261695795P 2012-08-31 2012-08-31
US201261695795P 2012-08-31
US201261711172P 2012-10-08 2012-10-08
US201261711172P 2012-10-08
US201313801748 2013-03-13
US13/801,748 US11261494B2 (en) 2012-06-21 2013-03-13 Method of measuring a fractional concentration of tumor DNA
PCT/IB2013/054898 WO2013190441A2 (en) 2012-06-21 2013-06-14 Mutational analysis of plasma dna for cancer detection

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ES2687847T3 true ES2687847T3 (es) 2018-10-29

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ES18185290T Active ES2894479T3 (es) 2012-06-21 2013-06-14 Análisis mutacional de ADN de plasma para la detección de cáncer
ES13807105.5T Active ES2687847T3 (es) 2012-06-21 2013-06-14 Análisis mutacional de ADN de plasma para la detección de cáncer

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ES18185290T Active ES2894479T3 (es) 2012-06-21 2013-06-14 Análisis mutacional de ADN de plasma para la detección de cáncer

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US (3) US11261494B2 (enExample)
EP (4) EP2864501B1 (enExample)
JP (4) JP6371280B2 (enExample)
KR (7) KR102720785B1 (enExample)
CN (3) CN104662168B (enExample)
AU (4) AU2013278994C1 (enExample)
CA (2) CA3080937A1 (enExample)
DK (2) DK2864501T3 (enExample)
EA (2) EA037292B1 (enExample)
ES (2) ES2894479T3 (enExample)
HU (1) HUE056915T2 (enExample)
IL (5) IL311127B2 (enExample)
MX (3) MX360264B (enExample)
PT (1) PT3456843T (enExample)
SG (2) SG10201808217WA (enExample)
TW (4) TW202328458A (enExample)
WO (1) WO2013190441A2 (enExample)
ZA (1) ZA201409281B (enExample)

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AU2020200122B2 (en) 2022-05-19
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KR20200035507A (ko) 2020-04-03
TW201920952A (zh) 2019-06-01
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